Bölüm "İstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Teknolojisi Bölümü, Farmasötik Teknoloji Ana Bilim Dalı" WoS İndeksli Yayınlar Koleksiyonu için listeleme
Toplam kayıt 35, listelenen: 21-35
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Improving therapeutic efficacy of voriconazole against fungal keratitis: Thermo-sensitive in situ gels as ophthalmic drug carriers
(Elsevier Science Bv, 2019)The aim of this research was to evaluate the potential use of in situ gel formulations for voriconazole ocular delivery as fungal keratitis treatment. The in situ gelling system was applied to increase residence time and ... -
Investigation of antimicrobial activities of some herbs containing essential oils and their mouthwash formulations
(Turkish Pharmacists Association, 2018)Objectives: The aim of this study was to prepare pharmaceutical formulations of mouthwashes and to examine the antimicrobial activities of essential oils obtained from plants used traditionally in Turkey for oral infections. ... -
Investigation of therapeutic effects in the wound healing of chitosan/pGM-CSF complexes
(Universidade de São Paulo, 2022)Granulocyte macrophage colony-stimulating factor (GM-CSF) has been shown to promote the growth, proliferation, and migration of endothelial and keratinocyte cells. Chitosan has been widely used as a biopolymer in wound-healing ... -
New therapeutic system based on hydrogels for vaginal candidiasis management: Formulation-characterization andin vitroevaluation based on vaginal irritation and direct contact test
(Taylor and Francis Ltd., 2020)The objective of the present research was to examine the possible usage of terbinafine loaded hydrogels for vaginal application as part of vaginal candidiasis treatment. Vaginal candidiasis belongs to the most frequent ... -
A novel approach for skin infections: Controlled release topical mats of poly (lactic acid)/poly(ethylene succinate) blends containing Voriconazole
(Elsevier Science Bv, 2018)The oral and injectable formulations of Voriconazole (VRZ), a known antifungal agent with low solubility, seem to cause severe side effects. Consequently, topical application of VRZ could be advantageous for skin fungal ... -
Novel benzydamine hydrochloride and chlorhexidine gluconate loaded bioadhesive films for local treatment of buccal infections
(Editions de Sante, 2023)Benzydamine hydrochloride (BZD), chlorhexidine gluconate (CHG) or their combination are frequently used as liquid dosage forms for the local treatment of buccal fungal and bacterial infections. However, the short residence ... -
Novel microemulsion containing benzocaine and fusidic acid simultaneously: Formulation, characterization, and in vitro evaluation for wound healing
(Springer Science and Business Media Deutschland GmbH, 2024)Modern drug carrier technologies, such as microemulsions with small droplet sizes and high surface areas, improve the ability of low water solubility active ingredients to permeate and localize. The goal of this study was ... -
Novel nanostructured lipid carrier based flurbiprofen loaded sodium alginate inserts for ocular drug delivery
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2016)The aim of the present study was to develop a novel Flurbiprofen (FLB) loaded nanostructured lipid carrier (NLC) based alginate inserts for treatment of ocular inflammation. 0.3% FLB loaded NLCs were prepared by means of ... -
Novel sprayable thermosensitive benzydamine hydrogels for topical application: Development, characterization, and in vitro biological activities
(Springer Science and Business Media Deutschland GmbH, 2023)Benzydamine hydrochloride (BZD) having analgesic, anesthetic, and anti-inflammatory effects is used orally or topically in the treatment of disorders such as joint inflammation and muscle pain. Within the scope of this ... -
Ophthalmic applications of SLN and NLC
(Bentham Science Publishers Ltd., 2017)Background: The eyes are among the most readily accessible organs in terms of location in the body, yet drug delivery to eye tissues is particularly problematic. The anatomy, physiology and biochemistry of the eye limit ... -
An optimization study on solid lipid nanoparticles using artificial neural network
(Colegio Farmaceuticos Provincia De Buenos Aires, 2017)Common use of supportive programs in finding the best in R&D studies provides positive results and thus ensures benefits to companies in terms of cost and time. The aim of this work was to develop, evaluate and optimize ... -
Preparation and evaluation of novel microemulsion-based hydrogels for dermal delivery of benzocaine
(Taylor & Francis Ltd, 2017)The purpose of the current research was to prepare and evaluate the potential use of microemulsion-based hydrogel (MBH) formulations for dermal delivery of benzocaine (BZN). The pseudoternary-phase diagrams were constructed ... -
Preparation, optimization and in vivo anti-inflammatory evaluation of hydroquinone loaded microemulsion formulations for melasma treatment
(Marmara University, 2019)The aim of the study is to evaluate the strengthening of penetration of the epidermis through the formulas containing hydroquinone in melasma treatment and development of alternative new carrier systems. During preparation ... -
Synthesis, structure elucidation and cytotoxic activities of 2,5-disubstituted-1,3,4-thiadiazole and l,2,4-triazole-3-thione derivatives
(Marmara University, 2022)In this study, a series of 1,3,4-thiadiazole (1b-9b) and l,2,4-triazole-3-thione (1c-9c) derivatives were synthesized. The reaction proses was carried out with the cyclocondensation of suitable 1,4-disubstituted thiosemicarbazide ... -
Two different approaches for oral administration of voriconazole loaded formulations: Electrospun fibers versus beta-cyclodextrin complexes
(MDPI, 2016)In this work, a comparison between two different preparation methods for the improvement of dissolution rate of an antifungal agent is presented. Poly(epsilon-caprolactone) (PCL) electrospun fibers and beta-cyclodextrin ...