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Toplam kayıt 135, listelenen: 121-130
Does sleep disturbance affect the amyloid clearance mechanisms in Alzheimer's disease?
(Wiley, 2017)
Sleep is an important factor that plays a key role in Alzheimer's disease pathogenesis. However, it is still unclear whether poor-quality sleep may overlap with sleep disturbances in the underlying dysfunctional mechanisms ...
Therapeutic role of rifampicin in Alzheimer's disease
(Wiley, 2018)
Rifampicin exerts significant brain protective functions in multiple experimental models. Here we summarize the underlying mechanisms of the neuroprotective and pro-cognitive effects of rifampicin that are mediated by its ...
Extracellular vesicles derived from neural progenitor cells--a preclinical evaluation for stroke treatment in mice (vol 12, pg 185, 2021)
(Springer, 2022)
In the version of this article initially published, there were errors on pages 5 and 6.
Evidence that osteogenic and neurogenic differentiation capability of epidural adipose tissue-derived stem cells was more pronounced than in subcutaneous cells
(Tübitak Scientific & Technical Research Council Turkey, 2020)
Background/aim: The management of dura-related complications, such as the repairment of dural tears and reconstruction of large dural defects, remain the most challenging subjects of neurosurgery. Numerous surgical techniques ...
Can Carpobrotus edulis, heal incisional and excisional wounds on the skin?
(Comenius University, 2021)
OBJECTIVES: This study aimed to investigate the wound healing activity of liposomal Carpobrotus edulis
powder extract (CEPE) formulation on incisional and excisional wounds in rat.
BACKGROUND: In the event of any damage, ...
Phosphodiesterase 10A deactivation induces long-term neurological recovery, peri-infarct remodeling and pyramidal tract plasticity after transient focal cerebral ischemia in mice
(Academic Press Inc., 2022)
The phosphodiesterase (PDE) superfamily comprises enzymes responsible for the cAMP and cGMP degradation to AMP and GMP. PDEs are abundant in the brain, where they are involved in several neuronal functions. High PDE10A ...
The role of circadian rhythm in the regulation of cellular protein profiles in the brain
(The Scientific and Technological Research Council of Turkey, 2021)
Background/aim: Circadian rhythm plays a significant role in the regulation of almost all kinds of physiological processes. In addition, it may also have a direct or indirect effect on the neurodegenerative processes, ...
Reduced folate carrier 1 is present in retinal microvessels and crucial for the inner blood retinal barrier integrity
(BioMed Central Ltd, 2023)
BackgroundReduced folate carrier 1 (RFC1; SLC19a1) is the main responsible transporter for the B9 family of vitamins named folates, which are essential for normal tissue growth and development. While folate deficiency ...
Nanodrugs for the treatment of ischemic stroke: A systematic review
(MDPI, 2023)
Ischemic stroke, a significant neurovascular disorder, currently lacks effective restorative medication. However, recently developed nanomedicines bring renewed promise for alleviating ischemia’s effects and facilitating ...
Preconditioned extracellular vesicles from hypoxic microglia reduce poststroke AQP4 depolarization, disturbed cerebrospinal fluid flow, astrogliosis, and neuroinflammation
(NLM (Medline), 2023)
Background: Stroke stimulates reactive astrogliosis, aquaporin 4 (AQP4) depolarization and neuroinflammation. Preconditioned extracellular vesicles (EVs) from microglia exposed to hypoxia, in turn, reduce poststroke brain ...