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Toplam kayıt 49, listelenen: 21-30
Pregabalin attenuates carrageenan induced acute inflammation in rats by inhibiting proinflammatory cytokine levels
(AVES, 2018)
Objective: Pregabalin (PGB) is a compound used in the treatment of epilepsy, anxiety, and neuropathic pain. Experimental data also indicate that PGB can reduce inflammatory pain. We aimed to investigate the anti-inflammatory ...
Can tissue factor, a multifactorial molecule of the hemostasis, be used as a biomarker for thrombosis, inflammation and cancer?
(University of Istanbul, 2017)
Tissue factor (TF) is a transmembrane protein found in many tissues and is active in various biological reactions. It is a member of the cytokine receptor superfam-ily and is referred to as CD 142 because of this feature. ...
Pleiotropic effects of pitavastatin: A pilot study using the saphenous vein endothelial cell model of endothelial injury and prevention of atherosclerosis
(Verduci Editore s.r.l, 2022)
OBJECTIVE: Cardiovascular diseases are responsible for the majority of deaths on a global scale. Atherosclerosis is the main risk factor for cardiovascular disorders and represents a complex phenomenon associated with ...
Disturbed endometrial NF-κB expression in women with recurrent implantation failure
(Verduci Publisher, 2016)
OBJECTIVE: This study was planned to investigate whether expression levels of endometrial NF-κB1 and NFκB p65 changes in women with recurrent implantation failure (RIF). PATIENTS AND METHODS: The study group consists of ...
Inflammation and congenital heart disease associated pulmonary hypertension
(Carden Jennings Publishing, 2015)
Background: Increased blood flow may trigger pulmonary arterial wall inflammation, which may influence progression of pulmonary artery hypertension in patients with congenital heart disease. In this study, we aimed to ...
Hepatocellular carcinomas with granulomatous inflammation in tumor stroma: Clinicopathologic characteristics
(Federation of Turkish Pathology Societies, 2022)
Objective: To determine the frequency of granulomatous inflammation within hepatocellular carcinoma (HCC) and its clinicopathologic associations.
Material and Method: Fifty-eight HCCs (51 explants, 3 lobectomies, and 4 ...
Potential biomarkers reflecting inflammation in patients with severe periodontitis: Fractalkine (CX3CL1) and its receptor (CX3CR1)
(Wiley, 2021)
Objective The aim of this study was to determine differences in GCF and serum levels of fractalkine/CX3CL1 and its receptor/ CX3CR1 between the patients with stage III/grade B periodontitis and periodontally healthy ...
Association of eosinophil-to-lymphocyte ratio with coronary slow-flow phenomenon in patients undergoing coronary angiography
(Termedia Publishing House, 2022)
Introduction: The current investigation intended to evaluate the correlation between eosinophil-to-lymphocyte ratio (ELR) and the coronary slow-flow phenomenon (CSFP) in patients undergoing elective coronary angiography. ...
Examination of antimicrobial effect of fluoxetine in experimental sepsis model: An in vivo study
(Wiley, 2023)
Since most infectious diseases can develop into sepsis, it is still a major medical problem. Some in-vivo studies showed promising properties of fluoxetine in the treatment of infections. This study aims the antimicrobial ...
Synthesis, characterization, COX1/2 inhibition and molecular modeling studies on novel 2-thio-diarylimidazoles
(Scientific Technical Research Council Turkey-Tubitak, 2021)
Heterocyclic compounds with diaryl substituents have been a milestone approach for selective cyclooxygenase 2 (COX 2) inhibition by bioisosteric replacements and modifications. It is also known that thiazole derivatives ...