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dc.contributor.authorKarabulut, Seda
dc.contributor.authorAksünger, Özlem
dc.contributor.authorKorkmaz, Oya
dc.contributor.authorEren Gozel, Hilal
dc.contributor.authorKeskin, İlknur
dc.date.accessioned2019-12-23T12:26:25Z
dc.date.available2019-12-23T12:26:25Z
dc.date.issued2019en_US
dc.identifier.citationKarabulut, S., Aksünger, Ö., Korkmaz, O., Eren Gozel, H. ve Keskin, İ. (2019). Intracytoplasmic morphologically selected sperm injection, but for whom? Zygote, 27(5), 299-304. https://doi.org/10.1017/S0967199419000297en_US
dc.identifier.issn0967-1994
dc.identifier.issn1469-8730
dc.identifier.urihttps://doi.org/10.1017/S0967199419000297
dc.identifier.urihttps://hdl.handle.net/20.500.12511/4613
dc.description.abstractIntracytoplasmic sperm injection (ICSI) is performed in cases of infertility by injecting a motile and morphologically normal sperm cell under a routine ×400 magnification at which is hard to distinguish morphologically healthy sperm. Recently, the use of high-powered differential interference contrast optics gave the opportunity to select a sperm under ultra-high magnification of ×10,160. The aim of the present study was to evaluate the efficacy of the intracytoplasmic morphologically selected sperm injection (IMSI) technique in different infertility populations undergoing ICSI. Main outcome measures of routine ICSI were compared with IMSI in three different groups of patients (1, non-selected; 2, male infertility; and 3, repeated implantation failure group). Results were analysed to evaluate the effects of the IMSI procedure and to find the most suitable group of patients who may benefit from the procedure. IMSI caused a significant increase in the fertilization and top quality embryo rates in the male infertility group and a significant increase in fertilization and pregnancy rates in the repeated implantation failure group, whereas no effect was observed in the non-selected group with patients of various indications. A positive effect of IMSI on the outcome of male factor infertility and repeated implantation failure patients was observed. Data observed confirmed that the application of IMSI was beneficial for a selected group of patients with male factor infertility and repeated implantation failure.en_US
dc.language.isoengen_US
dc.publisherCambridge University Pressen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectICSIen_US
dc.subjectIMSIen_US
dc.subjectSpermen_US
dc.subjectSperm Morphologyen_US
dc.subjectSperm Selectionen_US
dc.titleIntracytoplasmic morphologically selected sperm injection, but for whom?en_US
dc.typearticleen_US
dc.relation.journalZygoteen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Rektörlük, Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER)en_US
dc.authorid0000-0003-3302-5004en_US
dc.authorid0000-0003-2923-5869en_US
dc.authorid0000-0001-6026-6052en_US
dc.authorid0000-0002-7059-1884en_US
dc.identifier.volume27en_US
dc.identifier.issue5en_US
dc.identifier.startpage299en_US
dc.identifier.endpage304en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1017/S0967199419000297en_US


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