dc.contributor.author | Kaya, Başak | |
dc.contributor.author | Turhan, Uğur | |
dc.contributor.author | Sezer, Salim | |
dc.contributor.author | Kaya, Serdar | |
dc.contributor.author | Dağ, İsmail | |
dc.contributor.author | Tayyar, Ahmet | |
dc.date.accessioned | 2019-12-20T06:18:23Z | |
dc.date.available | 2019-12-20T06:18:23Z | |
dc.date.issued | 2020 | en_US |
dc.identifier.citation | Kaya, B., Turhan U., Sezer, S., Kaya S., Dağ, İ. ve Tayyar, A. (2020). Maternal serum galectin-1 and galectin-3 levels in pregnancies complicated withpreterm prelabor rupture of membranes. Journal of Maternal-Fetal and Neonatal Medicine, 33(5), 861-868. https://dx.doi.org/10.1080/14767058.2019.1637409 | en_US |
dc.identifier.issn | 1476-7058 | |
dc.identifier.issn | 1476-4954 | |
dc.identifier.uri | http://dx.doi.org/10.1080/14767058.2019.1637409 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/4570 | |
dc.description.abstract | Objective: To investigate maternal serum galectin-1 and galectin-3 levels in pregnancies complicated with preterm prelabor rupture of membranes (PPROM) and to compare with pregnancies delivered at term. Materials and methods: In this cross-sectional study, 40 women with singleton pregnancies complicated with PPROM between 24 and 34 weeks of gestation were compared with gestational age-matched 40 pregnant women with no obstetrics complications, who delivered at term. The maternal serum galectin-1 and galectin-3 levels were measured. Results: Patients complicated with PPROM had significantly higher levels of galectin-1 (p = .001) and galectin-3 (p = .003) than the control group. Maternal serum galectin-3 levels were found significantly negatively correlated with the gestational age at delivery and birth weight. Conclusion: Maternal serum galectin-1 and galectin-3 levels were significantly higher in pregnancies complicated with PPROM. Galectin-1 and galectin-3, with their regulatory effects in key biological processes, may be both an initiating factor in the pathophysiology of PPROM, a marker in the prediction, and a target of preventing strategies of PPROM. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Taylor and Francis Ltd | en_US |
dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
dc.subject | Galectin-1 | en_US |
dc.subject | Galectin-3 | en_US |
dc.subject | Lectins | en_US |
dc.subject | Preterm Birth | en_US |
dc.subject | Preterm Prelabor Rupture of Membranes | en_US |
dc.title | Maternal serum galectin-1 and galectin-3 levels in pregnancies complicated with preterm prelabor rupture of membranes | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Journal of Maternal-Fetal and Neonatal Medicine | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-2257-2355 | en_US |
dc.authorid | 0000-0003-1257-8742 | en_US |
dc.identifier.volume | 33 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.startpage | 861 | en_US |
dc.identifier.endpage | 868 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1080/14767058.2019.1637409 | en_US |
dc.identifier.wosquality | Q3 | en_US |
dc.identifier.scopusquality | Q2 | en_US |