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The effects of edaravone, a free-radical scavenger in lung injury induced by valproic acid demonstrated via different biochemical parameters
Bayrak, Bertan Boran; Yılmaz, Sebahat; Hacıhasanoğlu Çakmak, Neziha; Yanardağ, Refiye (Wiley, 2021)In this study, we aimed to evaluate whether edaravone (EDA) has a protective role against valproic acid (VPA)-induced lung damage via its antioxidative activity. Male Sprague-Dawley rats were split into four groups. Control ... -
Protective effect of edaravone on rat testis after valproic acid treatment
Çelik, Çağrı; Bayrak, Bertan Boran; Hacıhasanoğlu Çakmak, Neziha; Yanardağ, Refiye (Marmara University, 2022)Valproic acid n-dipropyl-acetic acid, VPA) is a medication used as anticonvulsant in the treatment of bipolar disorder, and for migraine prophylaxis. Long-term use of VPA is known to trigger reproductive impairment, which ...