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Toplam kayıt 33, listelenen: 21-30
Elevated β-hydroxybutyric acid with no ketoacidosis in type 2 diabetic patients using sodium-glucose cotransporter-2 inhibitors
(Elsevier, 2019)
SGLT2 inhibitor (SGLT2i) class of medications are known to cause to euglycemic diabetic ketoacidosis (euDKA) as reported in the article by Lin et al. in your esteemed publication about this entity being reported for the ...
The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20
(Nature Publishing Group, 2019)
TNF alpha is a pleiotropic cytokine which fuels tumor cell growth, invasion, and metastasis in some malignancies, while in others it induces cytotoxic cell death. However, the molecular mechanism by which TNF alpha exerts ...
Squalene attenuates the oxidative stress and activates AKT/mTOR pathway against cisplatin-induced kidney damage in mice
(Tubitak Scientific & Technical Research Council Turkey, 2019)
The clinical use of cisplatin, which is a first-line anticancer agent, is highly restricted due to its adverse effects on kidneys that lead to nephrotoxicity. Therefore, some potential reno-protective substances have been ...
Air quality (AQ) identification by innovative trend diagram and AQ index combinations in Istanbul megacity
(Turkish National Committee for Air Pollution and Control (TUNCAP), 2019)
Istanbul is one of the megacities with population over 14 million, where the most intensive economic and social human activities take place in Turkey with unprecedented energy consumption and extravagant life style. These ...
Role of erythropoietin and its receptor in the development of endometriosis in rats
(Galenos Yayıncılık, 2019)
Objective: Besides its hematopoietic function, erythropoietin (EPO) may protect tissues from degenerative disorders. As such, EPO and its receptors were revealed in nonhematopoietic cells, including stromal and endometrial ...
Synthesis of novel methyl jasmonate derivatives and evaluation of their biological activity in various cancer cell lines
(Academic Press Inc Elsevier Science, 2019)
Warburg hypothesized that the energy consumption of cancer cells is different than the normal cells. When compared to normal conditions, cancer cells do not undergo tricarboxylic acid (TCA) cycle therefore resulting in ...
Novel synthetic approaches for bisnaphthalimidopropyl (BNIP) derivatives as potential anti-parasitic agents for the treatment of leishmaniasis
(MDPI, 2019)
Leishmaniasis is a neglected parasitic disease that is widely seen in more than 60 countries worldwide, including Turkey and its subcontinental region. There are several chemotherapy agents for the treatment of leishmaniasis, ...
Acute and post-acute neuromodulation induces stroke recovery by promoting survival signaling, neurogenesis, and pyramidal tract plasticity
(Frontiers Media Sa, 2019)
Repetitive transcranial magnetic stimulation (rTMS) has gained interest as a non-invasive treatment for stroke based on the data promoting its effects on functional recovery. However, the exact action mechanisms by which ...
Identification of red blood cell membrane defects in a patient with hereditary spherocytosis using next-generation sequencing technology and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
(Spandidos Publ Ltd, 2019)
Hereditary spherocytosis (HS) is characterized by the morphological transformation of erythrocytes into a spherical shape due to a hereditary defect in cell membrane proteins (ghosts) associated with disruption of erythrocyte ...
A different view on the pathophysiology of Parkinson’s disease: A descendent neurochemical hypothesis?
(Wolters Kluwer, 2019)
It has been already shown that Parkinson’s disease (PD) is characterized by a prominent degeneration in substantia nigra (SN)neurons. Growing evidence suggests that there is a latent period of PD associated with slight ...