Ara
Toplam kayıt 21, listelenen: 11-20
Evidence that melatonin downregulates Nedd4-1 E3 ligase and its role in cellular survival
(Academic Press Inc Elsevier Science, 2019)
Indolamine melatonin structurally resembles non-covalent proteasome inhibitors; however, the role of ubiquitin proteasome system (UPS) in neuronal survival and how melatonin carries out UPS inhibition remain largely unknown. ...
Temperature difference relationship among precipitation, dry days, and spells in Turkey
(Springer Wien, 2019)
Strong logical relationships exist between temperature difference and hydro-meteorological variables such as precipitation, dry days, and dry spells. These relationships can be used for knowing how the differences of total ...
Cancer stem cells, their microenvironment and anoikis
(Begell House Inc., 2019)
Tumors are composed of a variety of cancer cells, all of which contribute to tumor heterogeneity. Among these populations of cells, cancer stem cells (CSCs) have an important role in the initiation and progression of cancer. ...
Proteomics analysis of CA1 region of the hippocampus in pre-, progression and pathological stages in a mouse model of the alzheimer’s disease
(Bentham Science Publishers, 2019)
Background: CA1 subregion of the hippocampal formation is one of the primarily affected structures in AD, yet not much is known about proteome alterations in the extracellular milieu of this region. Objective: In this ...
Compliance of medical biochemistry education in medical schools with national core education program 2014
(Walter De Gruyter Gmbh, 2019)
Background: Medical school curriculums are not standardized in Turkey and around the world, which results in great diversity in education. National Core Education Program (NCEP) has been prepared as a frame program and the ...
A different view on the platelet aggregation inhibitor clopidogrel - a well-suitable anti-oedema agent in a preclinical model of brain injury?
(Czech Medical Soc, 2019)
Aim: The neuroprotective effects of clopidogrel have already been shown in various experimental models. Taking into account the fact that clopidogrel is well tolerated and approved for use in various clinical settings, it ...
Inactivation of Magel2 suppresses oxytocin neurons through synaptic excitation-inhibition imbalance
(Academic Press Inc Elsevier Science, 2019)
Prader-Willi and the related Schaaf-Yang Syndromes (PWS/SYS) are rare neurodevelopmental disorders characterized by overlapping phenotypes of high incidence of autism spectrum disorders (ASD) and neonatal feeding difficulties. ...
Piecewise wet and dry spell duration-number relationship and possible climate change impact identification in Turkey
(Springer, 2019)
Wet (dry) spells correspond to successive surplus (deficit) in hydro-meteorology daily, weekly, monthly, or annual records according to above (below) of a given any threshold parameter value such as arithmetic average, ...
Electrophysiological evidence of altered facial expressions recognition in Alzheimer's disease: A comprehensive ERP study
(Elsevier Ireland Ltd, 2019)
Objectives: The present study aims to evaluate the amplitude and latency of event-related potentials (ERPs) P100, N170, VPP and N230 in individuals with Alzheimer's disease (AD) compared to healthy elderly controls, using ...
Wound healing effects of methanol extract of Laurocerasus officinalis roem
(Taylor & Francis Ltd, 2019)
Laurocerasus officinalis Roem. (syn: Prunus laurocerasus L.) is a member of Rosaceae family. We investigated the antimicrobial and antioxidant activity of L. officinalis Roem in wound healing both in vivo and in vitro using ...