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Toplam kayıt 49, listelenen: 31-40
Elevated β-hydroxybutyric acid with no ketoacidosis in type 2 diabetic patients using sodium-glucose cotransporter-2 inhibitors
(Elsevier, 2019)
SGLT2 inhibitor (SGLT2i) class of medications are known to cause to euglycemic diabetic ketoacidosis (euDKA) as reported in the article by Lin et al. in your esteemed publication about this entity being reported for the ...
The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20
(Nature Publishing Group, 2019)
TNF alpha is a pleiotropic cytokine which fuels tumor cell growth, invasion, and metastasis in some malignancies, while in others it induces cytotoxic cell death. However, the molecular mechanism by which TNF alpha exerts ...
Proteomics analysis of CA1 region of the hippocampus in pre-, progression and pathological stages in a mouse model of the alzheimer’s disease
(Bentham Science Publishers, 2019)
Background: CA1 subregion of the hippocampal formation is one of the primarily affected structures in AD, yet not much is known about proteome alterations in the extracellular milieu of this region. Objective: In this ...
Squalene attenuates the oxidative stress and activates AKT/mTOR pathway against cisplatin-induced kidney damage in mice
(Tubitak Scientific & Technical Research Council Turkey, 2019)
The clinical use of cisplatin, which is a first-line anticancer agent, is highly restricted due to its adverse effects on kidneys that lead to nephrotoxicity. Therefore, some potential reno-protective substances have been ...
Compliance of medical biochemistry education in medical schools with national core education program 2014
(Walter De Gruyter Gmbh, 2019)
Background: Medical school curriculums are not standardized in Turkey and around the world, which results in great diversity in education. National Core Education Program (NCEP) has been prepared as a frame program and the ...
Air quality (AQ) identification by innovative trend diagram and AQ index combinations in Istanbul megacity
(Turkish National Committee for Air Pollution and Control (TUNCAP), 2019)
Istanbul is one of the megacities with population over 14 million, where the most intensive economic and social human activities take place in Turkey with unprecedented energy consumption and extravagant life style. These ...
A different view on the platelet aggregation inhibitor clopidogrel - a well-suitable anti-oedema agent in a preclinical model of brain injury?
(Czech Medical Soc, 2019)
Aim: The neuroprotective effects of clopidogrel have already been shown in various experimental models. Taking into account the fact that clopidogrel is well tolerated and approved for use in various clinical settings, it ...
Role of erythropoietin and its receptor in the development of endometriosis in rats
(Galenos Yayıncılık, 2019)
Objective: Besides its hematopoietic function, erythropoietin (EPO) may protect tissues from degenerative disorders. As such, EPO and its receptors were revealed in nonhematopoietic cells, including stromal and endometrial ...
Synthesis of novel methyl jasmonate derivatives and evaluation of their biological activity in various cancer cell lines
(Academic Press Inc Elsevier Science, 2019)
Warburg hypothesized that the energy consumption of cancer cells is different than the normal cells. When compared to normal conditions, cancer cells do not undergo tricarboxylic acid (TCA) cycle therefore resulting in ...
Inactivation of Magel2 suppresses oxytocin neurons through synaptic excitation-inhibition imbalance
(Academic Press Inc Elsevier Science, 2019)
Prader-Willi and the related Schaaf-Yang Syndromes (PWS/SYS) are rare neurodevelopmental disorders characterized by overlapping phenotypes of high incidence of autism spectrum disorders (ASD) and neonatal feeding difficulties. ...