Ara
Toplam kayıt 45, listelenen: 21-30
Evidence that melatonin downregulates Nedd4-1 E3 ligase and its role in cellular survival
(Academic Press Inc Elsevier Science, 2019)
Indolamine melatonin structurally resembles non-covalent proteasome inhibitors; however, the role of ubiquitin proteasome system (UPS) in neuronal survival and how melatonin carries out UPS inhibition remain largely unknown. ...
Temperature difference relationship among precipitation, dry days, and spells in Turkey
(Springer Wien, 2019)
Strong logical relationships exist between temperature difference and hydro-meteorological variables such as precipitation, dry days, and dry spells. These relationships can be used for knowing how the differences of total ...
Nanoparticle-mediated histotripsy (NMH) using perfluorohexane 'nanocones'
(Institute of Physics Publishing, 2019)
Nanoparticle-mediated histotripsy (NMH) is an ultrasound treatment strategy that combines acoustically sensitive nanoparticles with histotripsy. Previous NMH studies using perfluorocarbon (PFC) nanodroplets (ND's), ∼200 ...
In vitro cytotoxicity evaluation of Marrubium vulgare L. methanol extract
(Marmara University, 2019)
Marrubium vulgare L. (Lamiaceae) is a herbal drug used for centuries for many diseases. In this present study the plant material was acquired from commercial sources in pharma grade (PhEur 8.0) quality. The methanol extract ...
Cancer stem cells, their microenvironment and anoikis
(Begell House Inc., 2019)
Tumors are composed of a variety of cancer cells, all of which contribute to tumor heterogeneity. Among these populations of cells, cancer stem cells (CSCs) have an important role in the initiation and progression of cancer. ...
Elevated β-hydroxybutyric acid with no ketoacidosis in type 2 diabetic patients using sodium-glucose cotransporter-2 inhibitors
(Elsevier, 2019)
SGLT2 inhibitor (SGLT2i) class of medications are known to cause to euglycemic diabetic ketoacidosis (euDKA) as reported in the article by Lin et al. in your esteemed publication about this entity being reported for the ...
The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20
(Nature Publishing Group, 2019)
TNF alpha is a pleiotropic cytokine which fuels tumor cell growth, invasion, and metastasis in some malignancies, while in others it induces cytotoxic cell death. However, the molecular mechanism by which TNF alpha exerts ...
Proteomics analysis of CA1 region of the hippocampus in pre-, progression and pathological stages in a mouse model of the alzheimer’s disease
(Bentham Science Publishers, 2019)
Background: CA1 subregion of the hippocampal formation is one of the primarily affected structures in AD, yet not much is known about proteome alterations in the extracellular milieu of this region. Objective: In this ...
Squalene attenuates the oxidative stress and activates AKT/mTOR pathway against cisplatin-induced kidney damage in mice
(Tubitak Scientific & Technical Research Council Turkey, 2019)
The clinical use of cisplatin, which is a first-line anticancer agent, is highly restricted due to its adverse effects on kidneys that lead to nephrotoxicity. Therefore, some potential reno-protective substances have been ...
Compliance of medical biochemistry education in medical schools with national core education program 2014
(Walter De Gruyter Gmbh, 2019)
Background: Medical school curriculums are not standardized in Turkey and around the world, which results in great diversity in education. National Core Education Program (NCEP) has been prepared as a frame program and the ...