ORCID "0000-0003-3302-5004" Rektörlüğe Bağlı Birimler için listeleme
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Artificial oocyte activation with calcium ionophore for frozen sperm cycles
Karabulut, Seda; Aksünger, Özlem; Ata, Can; Sağıroğlu, Yusuf; Keskin, İlknur (Taylor and Francis Ltd., 2018)Fertilization problems are the major problems that may be faced in 30-55% of the patients during an intracytoplasmic sperm injection (ICSI) cycle. A successful oocyte activation depends on factors related to both sperm and ... -
Chronic unpredictable stress disturbs the blood-testis barrier affecting sperm parameters in mice
Kolbaşı, Bircan; Bülbül, Muhammet Volkan; Karabulut, Seda; Erdem Altun, Ceren; Çakıcı, Çağrı; Ülfer, Gözde; Müdok, Tangül; Keskin, İlknur (Elsevier Ltd, 2021)Research question: Does chronic stress affect the key proteins and sperm parameters of the blood & ndash;testis barrier (BTB)? Design: C57Bl/6 mice were divided into two groups: a non-treated control group and a chronic ... -
Detailed morphological analysis of axolotl sperm
Keskin, İlknur; Gürsoy Gürgen, Duygu; Avinca, Didem; Özdemir, Ekrem Musa; Keskin, Suat Utku; Karabulut, Seda (Korean Society of Veterinary Science, 2021)The axolotl has extraordinary regeneration capacity compared to other vertebrates. This remarkable potential has been attributed to its life-long neoteny, characterized by the exhibition of embryonic characteristics at the ... -
Does a microfluidic chip for sperm sorting have a positive add-on effect on laboratory and clinical outcomes of intracytoplasmic sperm injection cycles? A sibling oocyte study
Yalçınkaya Kalyan, Ender; Can Çelik, Seren; Okan, Özlem; Akdeniz, Gülden; Karabulut, Seda; Çalışkan, Eray (Wiley, 2019)The most recent technologies for sperm sorting involve microfluidics. However, the most important question whether their use is of any advantage in terms of laboratory and clinical IVF/ICSI outcomes still remains controversy. ... -
Dondurulmuş ejekülat ve dondurulmuş testiküler spermin sonuçlarının intrasitoplazmik sperm enjeksiyonu (ICSI) parametrelerine etkisinin değerlendirilmesi
Karabulut, Seda; Korkmaz, Oya; Sağıroğlu, Yusuf; Keskin, İlknur (Avrasya Üroonkoloji Derneği, 2019)Amaç: Çalışmamızda, dondurulmuş ejekülat ve dondurulmuş testiküler spermin İntrasitoplaz - mik Sperm Enjeksiyonu (ICSI) sonuçları üzerine etkisinin araştırılması amaçlanmıştır. Gereç ve Yöntemler: Çalışmamızda 11.10.2016- ... -
Effects o follicular fluid oxidative status on human mural granulosa cells, oocyte competency and ICSI parameters
Karabulut, Seda; Korkmaz, Oya; Kutlu, Pelin; Eren Gözel, Hilal; Keskin, İlknur (Elsevier, 2020)Purpose: The aim of the present study was to understand the molecular and genetic alterations involved in follicular fluid oxidative process by investigating human mural granulosa cells and to find possible biomarkers for ... -
Effects of density gradient sperm preparation on semen parameters and acrosomal status
Keskin, İlknur; Karabulut, Seda (Haydarpaşa Sample Training and Research Hospital, 2017)AbstractIntroduction: The aim of this study was to observe changes in sperm parameters after density gradient sperm preparation. These data will help to decide upon preparation technique and to predict the outcome of semen ... -
Effects of gallic acid on endometrial cancer cells in two and three dimensional cell culture models
Bülbül, Muhammet Volkan; Karabulut, Seda; Kalender, Mervenur; Keskin, İlknur (Asian Pacific Organization for Cancer Prevention, 2021)Background and Aim: Cell culture studies are an indispensable tools used to understand basic physiological, biophysical and biomolecular mechanisms. Although traditional two-dimensional (2D) cell culture models are more ... -
Effects of human sperm cryopreservation on apoptotic markers in normozoospermic and non-normozoospermic patients
Karabulut, Seda; Demiroğlu Zergeroğlu, Asuman; Yılmaz, Elif; Kutlu, Pelin; Keskin, Ilknur (Cambridge University Press, 2018)The negative effects of cryopreservation on sperm parameters are well documented but little information is known about molecular basis of the process. The aim of the present study was to investigate the possible effects ... -
Factors related to follicular oxidative stress in intracytoplasmic sperm injection cycles and its effects on granulosa cells
Karabulut, Seda; Korkmaz, Oya; Kutlu, Pelin; Keskin, İlknur (Cambridge University Press, 2021)The aim of the present study was to investigate several common conditions that may potentially be correlated with follicular oxidative status during an intracytoplasmic sperm injection (ICSI) cycle and that include the ... -
A histopathological evaluation of ovarian hyperstimulation syndrome on reproductive and vital organs and the role of the VEGF-PKA pathway in a mouse model
Karabulut, Seda; Korkmaz, Oya; Erdem Altun, Ceren; Keskin, İlknur (Karger, 2021)Ovarian hyperstimulation syndrome (OHSS) is one of the most common and iatrogenic complications of in vitro fertilization therapy, which is an exaggerated response to excess hormones resulting in the development of a large ... -
Male infertility, azoozpermia and cryptozoospermia incidence among three infertility clinics in Turkey
Karabulut, Seda; Keskin, İlknur; Kutlu, Pelin; Delikara, Nuri; Atvar, Özhan; Öztürk, Metin İshak (AVES İbrahim Kara, 2018)Objective: Semen parameters are directly correlated with the infertility of the male. Incidence rates of male factor infertility, azoospermia and cryptozoospermia differ according to many factors such as geographic region, ... -
Quercetin enhances human sperm motility in a dose and time dependent manner
Karabulut, Seda; Korkmaz, Oya; Erdem Altun, Ceren; Demiroğlu Zergeroǧlu, Asuman; Keskin, İlknur (Istanbul Medipol University, 2020)The aim of this study was to investigate the effect of quercetin on the motility of ejaculated human spermatozoa in asthenozoospermic cases by using different doses and exposure times. Semen samples of 94 men were incubated ... -
Seminal trace elements and their relationship with sperm parameters
Karabulut, Seda; Korkmaz, Serol; Güneş, Ertuğrul; Kabil, Erol; Keskin, İlknur; Usta, Melek; Omurtag, Gülden Zehra (Wiley, 2022)Male reproductive problems may derive from many reasons including the environmental toxicants which may either intaken by occupational exposure, nutrition or bad air quality. The increased exposure to these substances due ... -
Sperm selection with Annexin-V coated polystrene bead technique (APB-Tech): A novel and reliable method for the microscopic selection of viable and non-apoptotic sperm to be used for intracytoplasmic sperm injection
Karabulut, Seda; Yalım Camcı, İrem; Atambay, Can; Yiğit, Pakize; Keskin, İlknur (Elsevier Inc., 2022)Infertility is a growing health problem that affects 20% of couples who want to conceive. ‘Intracytoplasmic sperm injection’ (ICSI) is a commonly used assisted reproduction treatment technique that offers the couples to ...