ORCID "0000-0003-2251-2093" Rektörlüğe Bağlı Birimler için listeleme
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Phosphorylation of PI3K/Akt at Thr308, but not phosphorylation of MAPK kinase, mediates lithium-induced neuroprotection against cerebral ischemia in mice
Ateş, Nilay; Çağlayan, Aysun; Balçıkanlı, Zeynep; Sertel, Elif; Beker, Mustafa Çağlar; Dilsiz, Pelin; Çağlayan, Ahmet Burak; Çelik, Süleyman; Daşdelen, Muhammed Furkan; Çağlayan, Berrak; Yiğitbaşı, Türkan; Özbek, Hanefi; Doeppner, Thorsten Roland; Hermann, Dirk Matthias; Kılıç, Ertuğrul (Academic Press Inc., 2022)Lithium, in addition to its effect on acute and long-term bipolar disorder, is involved in neuroprotection after ischemic stroke. Yet, its mechanism of action is still poorly understood, which was only limited to its ... -
Social isolation initiated post-weaning augments ischemic brain injury by promoting pro-inflammatory responses
Daşdelen, Muhammed Furkan; Çağlayan, Ahmet Burak; Er, Sezgin; Beker, Mustafa Çağlar; Ateş, Nilay; Gronewold, Janine; Doeppner, Thorsten Roland; Hermann, Dirk M.; Kılıç, Ertuğrul (Academic Press Inc., 2024)Social isolation is associated with poor stroke outcome, but the underlying molecular mechanisms were largely unknown. In male Balb/C mice exposed to transient middle cerebral artery occlusion (MCAo), we examined the effects ... -
The unconventional growth factors cerebral dopamine neurotrophic factor and mesencephalic astrocyte-derived neurotrophic factor promote post-ischemic neurological recovery, perilesional brain remodeling, and lesion-remote axonal plasticity
Çağlayan, Ahmet Burak; Beker, Mustafa Çağlar; Sertel Evren, Elif; Çağlayan, Berrak; Kılıç, Ülkan; Ateş, Nilay; Çağlayan, Aysun; Daşdelen, Muhammed Furkan; Doeppner, Thorsten Roland; Saarma, Mart; Hermann, Dirk Matthias; Kılıç, Ertuğrul (Springer, 2023)Considerable efforts are currently made to develop strategies that boost endogenous recovery once a stroke has occurred. Owing to their restorative properties, neurotrophic factors are attractive candidates that capitalize ...