ORCID "0000-0003-2075-7724" Rektörlüğe Bağlı Birimler için listeleme
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Adrenergic modulation of melanocortin pathway by hunger signals
Sayar Atasoy, Nilüfer; Laule, Connor; Aklan, İltan; Kim, Hyojin; Yavuz, Yavuz; Ateş, Tayfun; Çoban, İlknur; Köksalar Alkan, Fulya; Rysted, Jacob; Davis, Debbie; Singh, Uday; Alp, Muhammed İkbal; Yılmaz, Bayram; Cui, Huxing; Atasoy, Deniz (Nature Research, 2023)Norepinephrine (NE) is a well-known appetite regulator, and the nor/adrenergic system is targeted by several anti-obesity drugs. To better understand the circuitry underlying adrenergic appetite control, here we investigated ... -
An improved platform for cultured neuronal network electrophysiology: Multichannel optogenetics integrated with MEAs
Bayat, Fazlı Kemal; Alp, Muhammed İkbal; Bostan, Sevginur; Gülçür, Halil Özcan; Öztürk, Gürkan; Güveniş, Albert (Springer, 2022)Cultured neuronal networks (CNNs) are powerful tools for studying how neuronal representation and adaptation emerge in networks of controlled populations of neurons. To ensure the interaction of a CNN and an artificial ... -
NTS catecholamine neurons mediate hypoglycemic hunger via medial hypothalamic feeding pathways
Aklan, İltan; Sayar Atasoy, Nilufer; Yavuz, Yavuz; Ateş, Tayfun; Çoban, İlknur; Köksalar, Fulya; Filiz, Gizem; Topçu, İskalen Cansu; Öncül, Merve; Dilsiz, Pelin; Cebecioğlu, Utku; Alp, Muhammed İkbal; Yılmaz, Bayram; Davis, Deborah R.; Hajdukiewicz, Karolina; Saito, Kenji; Konopka, Witold; Cui, Huxing; Atasoy, Deniz (Cell Press, 2020)Glucose is the essential energy source for the brain, whose deficit, triggered by energy deprivation or therapeutic agents, can be fatal. Increased appetite is the key behavioral defense against hypoglycemia; however, the ...