Scopus Q Kategorisi "Q2" Rektörlüğe Bağlı Birimler İçin Listeleme
Toplam kayıt 139, listelenen: 81-100
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Leptin in sperm analysis can be a new indicator
(Elsevier GMBH, 2019)Purpose Radiotherapy, chemotherapy, various tumors and invasive surgery can result in ejaculatory dysfunction and testicular insufficiency. Sperm cryopreservation is the only method which can provide a baby for couples. ... -
Long-term treatment with chloroquine increases lifespan in middle-aged male mice possibly via autophagy modulation, proteasome inhibition and glycogen metabolism
(Impact Journals LLC, 2022)Previous studies have shown that the polyamine spermidine increased the maximum life span in C. elegans and the median life span in mice. Since spermidine increases autophagy, we asked if treatment with chloroquine, an ... -
Lower prepulse inhibition in clinical high-risk groups but not in familial risk groups for psychosis compared with healthy controls
(Wiley, 2020)Aim: Although the lower level of prepulse inhibition (PPI) of the startle response is well known in schizophrenia, the onset of this difference is not clear. The aim of the present study was to compare PPI in individuals ... -
Melatonin affects the release of exosomes and tau-content in in vitro amyloid-beta toxicity model
(Elsevier Science Ltd., 2020)Background: Recent studies have been revealed that oxidative damage is the main cause of aging and age-related neurodegenerative diseases like Alzheimer's disease (AD). Melatonin is secreted from the pineal gland and its ... -
Microbiome and longevity: High abundance of longevity-linked muribaculaceae in the gut of the long-living rodentspalax leucodon
(Mary Ann Liebert Inc, 2020)With a world population living longer as well as marked disparities in life expectancy, understanding the determinants of longevity is one of the priority research agendas in 21st century life sciences. To this end, the ... -
Minocycline increases in-vitro cortical neuronal cell survival after laser induced axotomy
(2020)Antibiotic therapies targeting multiple regenerative mechanisms have the potential for neuroprotective effects, but the diversity of experimental strategies and analyses of non-standardised therapeutic trials are challenging. ... -
The modulation of delta responses in the interaction of brightness and emotion
(Elsevier Science Bv, 2017)The modulation of delta oscillations (0.5-3.5 Hz) by emotional stimuli is reported. Physical attributes such as color, brightness and spatial frequency of emotional visual stimuli have crucial effect on the perception of ... -
Modulation of oxidative stress and Ca2+ mobilization through TRPM2 channels in rat dorsal root ganglion neuron by Hypericum perforatum
(Pergamon-Elsevier Science Ltd., 2014)A main component of St. John's Wort (Hypericum perforatum, HP) is hyperforin which has antioxidant properties in dorsal root ganglion (DRG) neurons, due to its ability to modulate NADPH oxidase and protein kinase C. Recent ... -
Multiple sclerosis biomarker candidates revealed by cell-type-specific interactome analysis
(Mary Ann Liebert, 2022)Multiple sclerosis (MS) is a demyelinating disorder that affects multiple regions of the central nervous system such as the brain, spinal cord, and optic nerves. Susceptibility to MS, as well as disease progression rates, ... -
Mutant SOD1 protein increases Na(v)1.3 channel excitability
(Springer, 2016)Amyotrophic lateral sclerosis (ALS) is a lethal paralytic disease caused by the degeneration of motor neurons in the spinal cord, brain stem, and motor cortex. Mutations in the gene encoding copper/zinc superoxide dismutase ... -
Myelin disorders and stem cells: As therapies and models
(Tubitak Scientific & Technical Research Council, 2016)Myelin disorders burden millions of people around the world, yet existing therapies are inadequate to cure them. Current remedies commonly treat the symptoms with minimal to no effect on the actual cause of the disorder. ... -
Neuroimaging-guided transcranial magnetic and direct current stimulation in MCI: Toward an individual, effective and disease-modifying treatment
(SAGE Publications Inc, 2023)The therapeutic approaches currently applied in Alzheimer's disease (AD) and similar neurodegenerative diseases are essentially based on pharmacological strategies. However, despite intensive research, the effectiveness ... -
The neuroprotective effect of focused ultrasound: New perspectives on an old tool
(Pergamon-Elsevier Science Ltd., 2017)Introduction Transcranial focused ultrasound (tFUS) is a novel technique that can noninvasively modulate the cortical function. Moreover, there are rapidly replicating evidence suggesting the role of tFUS for targeted ... -
Neuroprotective effect of lithium in cold- induced traumatic brain injury in mice
(Elsevier, 2020)Apart from its well-established therapeutic activity on bipolar disorder and depression, lithium exerts neuroprotective activity upon neurodegenerative disorders, such as traumatic brain injury (TBI). However, the cellular ... -
Neuropsychiatric outcomes and caregiver distress in primary progressive aphasia
(Wiley, 2023)Background: In this study, we aimed to outline the neuropsychiatric consequences of primary progressive aphasia (PPA) and to understand how neuropsychiatric symptomatology affects distress in caregivers. Methods: The ... -
New bone-generative effect of Salvia officinalis L. in the expanded midpalatal suture An in vivo and in vitro study
(Urban & Vogel, 2022)Purpose The aims of this study were to evaluate the effects of systemic administration of Salvia officinalis Linnaeus (L.) leaf extract on new bone formation in the expanded premaxillary suture in rats in vivo and to examine ... -
Normobaric oxygen treatment improves neuronal survival functional recovery and axonal plasticity after newborn hypoxia-ischemia
(Elsevier, 2020)Background: Newborn hypoxia ischemia (HI) is one of the most prevalent cases in the emergency and can result from fetal hypoxia during delivery. In HI, restricted blood supply to the fetal brain may cause epilepsy or mental ... -
Novel insight into wound healing properties of methanol extract of Capparis ovata Desf. var. palaestina Zohary fruits
(Wiley, 2018)ObjectivesThe objective of this study was to investigate the wound healing activity of Capparis ovata var. palaestina fruit extract in mice. For this aim, wound healing, invitro antimicrobial and antioxidant activities, ... -
Novel β‑hydroxy ketones: Synthesis, spectroscopic characterization, molecular docking, and anticancer activity studies
(Elsevier B. V., 2022)In this study, a series of novel β‑hydroxy ketone derivatives 3a-o were designed, synthesized, and evaluated for their anticancer activity. The structure of these compounds were characterized by IR, 1H and 13C NMR, mass ... -
Oleamide, a sleep-inducing compound: Effects on Ion channels and cancer
(Mary Ann Liebert Inc., 2022)Primary fatty acid amides (PFAMs) are interesting lipid-derived signaling molecules with wide-ranging actions, including bioelectric. In this perspective, we evaluate a possible triangular relationship: PFAMs-ion ...