Güncel Gönderiler: Makale Koleksiyonu
Toplam kayıt 356, listelenen: 1-20
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Hexokinase 1 forms rings that regulate mitochondrial fission during energy stress
(2024)Metabolic enzymes can adapt during energy stress, but the consequences of these adaptations remain understudied. Here, we discovered that hexokinase 1 (HK1), a key glycolytic enzyme, forms rings around mitochondria during ... -
Remote monitoring app for endocrine therapy adherence among patients with early-stage breast cancer: a randomized clinical trial
(2024)Importance: Adjuvant endocrine therapy (AET) use among women with early-stage, hormone receptor-positive breast cancer reduces the risk of cancer recurrence, but its adverse symptoms contribute to lower adherence. Objective: ... -
Global practice patterns in the evaluation of non-obstructive azoospermia: results of a world-wide survey and expert recommendations
(2024)Purpose: Non-obstructive azoospermia (NOA) represents the persistent absence of sperm in ejaculate without obstruction, stemming from diverse disease processes. This survey explores global practices in NOA diagnosis, ... -
Global practice patterns and variations in the medical and surgical management of non-obstructive azoospermia: results of a world-wide survey, guidelines and expert recommendations
(2024)Purpose: Non-obstructive azoospermia (NOA) is a common, but complex problem, with multiple therapeutic options and a lack of clear guidelines. Hence, there is considerable controversy and marked variation in the management ... -
IMpassion132 double-blind randomised phase III trial of chemotherapy with or without atezolizumab for early relapsing unresectable locally advanced or metastatic triple-negative breast cancer
(2024)Background: Immune checkpoint inhibitors improve the efficacy of first-line chemotherapy for patients with programmed death-ligand 1 (PD-L1)-positive unresectable locally advanced/metastatic triple-negative breast cancer ... -
Use of geological maps in detecting asbestos-related diseases; a new region in Anatolia
(2024)Objective: To examine the potential relationship between the presence of asbestos-related diseases (ARDs) in the region of Kastamonu, Turkey. Methods: The birthplaces of patients with ARDs and control subjects diagnosed ... -
Supratherapeutic utilization of paracetamol versus ibuprofen among <12-year-old children in primary care in Istanbul
(2024)Background: Paracetamol and ibuprofen are the most preferred analgesics for pain and fever management in children. Prescribing of these drugs in supratherapeutic doses may predispose to their toxicity. We aimed to compare ... -
Effectiveness of intermittent theta burst stimulation to enhance upper extremity recovery after stroke: A randomized controlled study
(2024)Objective: To first investigate the effectiveness of modified Constraint-Induced Movement Therapy (mCIMT) in low-functioning patients with stroke (PwS). Second, we aimed to investigate the efficiency of intermittent ... -
Stenotrophomonas maltophilia outbreak originating from a pull-out faucet in a pediatric intensive care unit in Turkey: Insights from clinical records and molecular typing
(2024)Background: Nosocomial Stenotrophomonas maltophilia-related cases are rising and pose a threat to immunocompromised patients. Twelve patients from our pediatric intensive care unit (PICU) presented with S maltophilia-associated ... -
Priming constraint-induced movement therapy with intermittent theta burst stimulation to enhance upper extremity recovery in patients with stroke: protocol for a randomized controlled study
(2024)Background: The treatments based on motor control and motor learning principles have gained popularity in the last 20 years, as well as non-invasive brain stimulations that enhance neuroplastic changes after stroke. However, ... -
Ultrasound guided quadro-iliac plane block: Another novel fascial plane block
(2024)Study objective: We report a novel block technique aimed to provide lumbosacral, abdominal, and hip analgesia: The quadro-iliac plane (QIP) block. Design: A cadaveric examination that evaluates the spread of QIP block. ... -
Use of lipid-lowering drugs in restricted health access settings: Results from the trends in drug utilization during covıd-19 pandemic in Turkey (PANDUTI-TR) study
(2024)Background: COVID-19 restrictions prompted changes in chronic disease management and lifestyle modifications, potentially altering cardiometabolic indicators and lipid-lowering pharmacotherapy patterns. We aimed to assess ... -
Reassessing normal voiding standards: A cross-sectional study based on medical professionals’ evaluations with portable uroflowmetry and IPSS
(2024)Background/Objectives: LUTS and voiding dysfunctions are prevalent in urology clinics, with uroflowmetry and IPSS as the prevailing diagnostic methods. Nevertheless, objective assessment can be constrained by age, gender, ... -
Prognostic factor risk groups for clinical stage ı seminoma: An individual patient data analysis by the european association of urology testicular cancer guidelines panel and guidelines office
(2024)BACKGROUND: The relapse rate in patients with clinical stage I (CSI) seminomatous germ cell tumor of the testis (SGCTT) who were undergoing surveillance after radical orchidectomy is 4-30%, depending on tumor size and rete ... -
Kidney-sparing surgery has equivalent oncological outcomes to radical nephroureterectomy for ureteral urothelial carcinoma
(2024)INTRODUCTION AND OBJECTIVE: Kidney-sparing surgery (KSS) for upper tract urothelial cancer (UTUC) has gained increasing interest recently. However, there is limited contemporary data regarding the role of KSS in ureteral ... -
The status of spermatogenesis in germ cell tumor bearing testis and its association with metastatic disease
(2024)Introduction: We aimed to evaluate the status of spermatogenesis detected by histological examination of non-tumoral testicular tissues in tumor bearing testis and its association with advanced stage disease. Patients and ... -
The relationship between urinary incontinence, osteoarthritis, and musculoskeletal system disorders
(2024)Background/Objectives: Urinary incontinence diminishes quality of life, and its severity can be worsened by mobility impairments. This study explored the link between urinary incontinence, osteoarthritis, and back ... -
Physical and mental health characteristics of hospitalized covid-19 patients with and without type 2 diabetes mellitus in Turkey
(2024)The aim of this study was to assess the rates of depression, anxiety, and stress and quality of sleeping among COVID-19 patients with and without type 2 diabetes mellitus (T2DM). A case and control design has been employed, ... -
Should breastfeeding be interrupted after radiological imaging examinations? Evidence and clinical applications
(2024)Purpose: Breastfeeding provides optimal growth and development for infants. Lactating mothers may have challenges maintaining breastfeeding, and one of those challenges is being falsely advised to interrupt breastfeeding ... -
Super-mini PCNL (SMP) with suction versus standard PCNL for the management of renal calculi of 1.5 cm-3 cm: a randomized controlled study from a university teaching hospital
(2024)Purpose: To assess the safety and efficacy of super-mini PCNL (SMP, 14 Fr) when compared to standard PCNL (sPCNL, 24–30 Fr) in the management of renal calculi of size ranging from 1.5 to 3 cm. Methods: From February 2021 ...