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Toplam kayıt 17, listelenen: 1-10
Protein and gene delivery systems for neurodegenerative disorders: Where do we stand today?
(MDPI, 2022)
It has been estimated that every year, millions of people are affected by neurodegenerative disorders, which complicate their lives and their caregivers’ lives. To date, there has not been an approved pharmacological ...
Physiological and pharmacological roles of melatonin in the pathophysiological components of cellular injury after ischemic stroke
(NLM (Medline), 2020)
Apart from its metabolic or physiological functions, melatonin has a potent cytoprotective activity in the physiological and pathological conditions. It is synthetized by the pineal gland and released into the blood ...
Editorial: Immune-modulatory effects of vitamin D
(Frontiers Media S.A., 2020)
Vitamin D plays an essential role in bone development. However, recent studies are beginningto uncover its role as a modulator of the immune system (1). Several reports have shownassociations between vitamin D deficiency ...
Systematic review and meta-analysis of tocilizumab therapy versus standard of care in over 15,000 COVID-19 pneumonia patients during the first eight months of the pandemic
(MDPI, 2021)
Background. Tocilizumab is an anti-IL-6 therapy widely adopted in the management of the so-called "cytokine storm" related to SARS-CoV-2 virus infection, but its effectiveness, use in relation to concomitant corticosteroid ...
COVID-19 vaccination and the rate of immune and autoimmune adverse events following immunization: Insights from a narrative literature review
(Frontiers Media S.A., 2022)
Despite their proven efficacy and huge contribution to the health of humankind, vaccines continue to be a source of concern for some individuals around the world. Vaccinations against COVID-19 increased the number of ...
Hedgehog signaling: Linking embryonic lung development and asthmatic airway remodeling
(MDPI, 2022)
The development of the embryonic lung demands complex endodermal-mesodermal interactions, which are regulated by a variety of signaling proteins. Hedgehog (Hh) signaling is vital for lung development. It plays a key ...
Complications and outcomes of tubeless versus nephrostomy tube in percutaneous nephrolithotomy: A systematic review and meta-analysis of randomized clinical trials
(Springer, 2022)
We aimed to perform a systematic review of randomized trials to summarize the evidence on the safety and stone-free rate after Tubeless percutaneous nephrolithotomy (PCNL) (ureteral stent/catheter, no nephrostomy) compared ...
HIV pre-exposure prophylaxis and its impact on the gut microbiome in men having sex with men
(Frontiers Media S.A., 2022)
HIV/AIDS still imposes a high epidemiological and societal burden. Together with antiretroviral therapy, pre-exposure prophylaxis (PrEP) represents a fundamental tool in the fight against HIV/AIDS. PrEP is considered ...
Robotic-assisted simple prostatectomy: A systematic review
(MDPI, 2020)
Contemporary minimally invasive surgical (MIS) treatment options of patients with male Lower Urinary Tract Symptoms (LUTS) in men with prostate glands >80 mL include Holmium Laser Enucleation Prostate (HoLEP), Thulium laser ...