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DNA methylation pattern of TM6SF2 influences NAFLD progression in genotype-dependent manner
(Elsevier Science Bv, 2019)Background and aims: Non-alcoholic fatty liver disease (NAFLD) arises due to complex interaction of genetic and environmental factors. Evidence suggests that transmembrane 6 superfamily member 2 (TM6SF2) E167K variant is ... -
Effect of social isolation on the brain injury following focal cerebral ischemia in mice and proteomic approach for identifying possible cellular pathways
(Wiley, 2021)Social isolation has become a significant part of our everyday life during the Covid-19 pandemic, resulting in drastic effects on physiological wellbeing. It was shown that loneliness or psychosocial stress such as social ... -
Floresan mikroskop görüntülerinde miyelin segmentasyonu
(Institute of Electrical and Electronics Engineers Inc., 2019)Aksonların etrafına sarılmış¸ miyelin kılıf, hızlı bir şekilde sinyal iletimini sağlar ve deformasyonu, Multipl Skleroz (MS) gibi çeşitli nörodejeneratif hastalıklara neden olur. Aday ilaç geliştirilmesi için, miyelinizasyonun ... -
Investigating side effects of existing drugs used in Covid-19 treatment
(Institute of Electrical and Electronics Engineers Inc., 2020)Following the rapid spread and evolution of the novel Corona virus starting in December 2019, the lack of a vaccine or a medication that proved to be effective for Covid-19 was addressed as a major concern by the World ... -
The investigation of genetic etiology in familial cases with congenital hypothyroidism
(Karger, 2019)Background: Congenital hypothyroidism(CH) is the most common neonatal endocrinological disorder in the world. Although most of the CH is sporadic, some genetic defects are responsible from the etiology. The aim of this ... -
Pancreatic tumor detection by convolutional neural networks
(Institute of Electrical and Electronics Engineers Inc., 2022)Artificial Intelligence and its sub-branches like Machine Learning (ML) and Deep Learning (DL) applications have the potential to have positive effects that can directly affect human life. Medical imaging provides a way ... -
Which ultrasound or MRI characteristics demonstrate the highest diagnostic accuracy in identifying malignancy in males with indeterminate lesions of the testis? A systematic review
(Elsevier, 2021)Introduction & Objectives: The use of Scrotal Ultrasound (SUS) has resulted in increased detection of indeterminate testicular lesions, resulting in a clinical and management challenge. The gold standard of treatment has ...