ORCID "0000-0002-9710-8653" Makale Koleksiyonu için listeleme
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Chronic neutropenia in childhood: Laboratory and clinical features
Nepesov, Serdar; Yaman, Yöntem; Elli, Murat; Bayram, Nihan; Özdilli, Kürşat; Ayaz, Akif; Anak, Sema (Springer India, 2022)Objectives To describe the clinical characteristics of patients with chronic neutropenia. Methods Data of 36 patients with chronic neutropenia, who were followed up in the authors' clinic between May 2013 and May 2020, ... -
Clinical efficacy of ruxolitinib monotherapy and haploidentical hematopoeitic stem cell transplantation in a child with philadelphia chromosome-like relapsed/refractory acute lymphoblastic leukemia
Bayram, Nihan; Yaman, Yöntem; Özdilli, Kürşat; Telhan, Leyla; Nepesov, Serdar; Bilgen, Hülya; Elli, Murat; Behar, Sude Sema; Anak, Sema (Wiley, 2021)Introduction (Ph-like) ALL is a subset of leukemia which has a gene expression profile similar to Ph+disease, but without the presence of BCR-ABL1 translocation. Case description We reported an exceptional case of a ... -
Clinical, genetic, and outcome characteristics of pediatric patients with primary hemophagocytic lymphohistiocytosis
Nepesov, Serdar; Yaman, Yöntem; Elli, Murat; Bayram, Nihan; Özdilli, Kürşat; Kıykım, Ayça; Çakır, Deniz; Kılıç, Betül; Aydın, Kürşad; Ayaz, Akif; Telhan, Leyla; Anak, Sema (AVES, 2022)Objectİive: In this study, we sought to describe the clinical, laboratory, and genetic characteristics of patients diagnosed with primary hemophagocytic lymphohistiocytosis. Thus, we aimed to evaluate the early diagnosis ... -
Eltrombopag for treatment of thrombocytopenia after allogeneic hematopoietic cell transplantation in children: Single-centre experience
Yaman, Yöntem; Elli, Murat; Şahin, Şifa; Özdilli, Kürşat; Bilgen, Hülya; Bayram, Nihan; Nepesov, Serdar; Anak, Sema (Wiley, 2021)Delayed recovery of thrombocytopenia is a well-known complication after allogeneic HSCT. Eltrombopag (ELT), a thrombopoietin receptor agonist (TRAs), induces platelet maturation and release. Mostly conducted in adults, ... -
Evaluation of the demographic and clinical findings of pediatric patients that developed acute graft-versus-host disease after allogeneic hematopoietic stem cell
Yüksel, Mavişe; Yaman, Yöntem; Elli, Murat (2020)Aim: Acute graft-versus-host disease (GVHD) is an complication after allogeneic hematopoietic stem cell transplantation (alloHSCT), manifesting with an erythematous maculopapular rash followed by liver disease and dysfunctions ... -
Hematopoietic stem cell transplantation in patients with severe combined immunodeficiency: A single-center experience
Nepesov, Serdar; Yaman, Yöntem; Elli, Murat; Bayram, Nihan; Özdilli, Kürşat; Kıykım, Ayça; Anak, Sema (Istanbul University, 2022)Objective: The aim of this study was to determine the factors affecting outcomes in patients who underwent hematopoietic stem cell transplantation (HSCT) with the diagnosis of severe combined immunodeficiency (SCID). ... -
HLA - matched related donor hematopoietic stem cell transplantation in a patient with polynucleotide kinase 3-phosphatase mutation developed acute myeloid leukemia
Bayram, Nihan; Yaman, Yöntem; Elli, Murat; Özdilli, Kürşat; Nepesov, Serdar; Doğan, Mehmet Sait; Ayaz, Akif; Anak, Sema (Wiley, 2022)Background PNPK gene mutations result in DNA repair disorders and have a spectrum of neurodevelopmental manifestations. To date, cancer predisposition has not been described in patients with PNKP mutations. Observation ... -
Hodgkin lenfoma nüks ve/veya kemoterapi dirençli olgularda hematopoetik kök hücre nakli ve yüksek doz kemoterapi: Tek merkez deneyimi
Yaman, Yöntem; Elli, Murat; Özdilli, Kürşat; Telhan, Leyla; Bayram, Nihan; Hazar, Volkan; Tuprul Sarıbeyoğlu, Ebru; Şahin, Şifa; Anak, Sema (İstanbul Üniversitesi, 2021)Giriş: Standart tedavi alan Hodgkin Lymphoma (HL) hastalarının yaklaşık %20’sinde hastalık dirençli seyredebilir veya tekrar edebilir. Tekrar eden/ dirençli HL’da standart tedavi yüksek doz kemoterapi ve takip eden otolog ... -
Prognostic factors for survival in children who relapsed after allogeneic hematopoietic stem cell transplantation for acute leukemia
Hazar, Volkan; Tezcan Karasu, Gülsün; Öztürk, Gülyüz; Küpesiz, Alphan; Aksoylar, Serap; Özbek, Namık; Uygun, Vedat; İleri, Talia; Visal Okur, Fatma; Koçak, Ülker; Çakı Kılıç, Suar; Akçay, Arzu; Güler, Elif; Kansoy, Savaş; Karakükcü, Musa; Bayram, İbrahim; Aksu, Tekin; Yeşilipek, Akif; Karagün, Barbaros Şahin; Yılmaz, Şebnem; Ertem, Mehmet; Uçkan, Duygu; Fışgın, Tunç; Gürsel, Orhan; Yaman, Yöntem; Bozkurt, Ceyhun; Gökçe, Müge (Wiley, 2021)Background Post-transplant relapse has a dismal prognosis in children with acute leukemia undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). Data on risk factors, treatment options, and outcomes are ... -
Talasemi majör ve intermedia hastalarında HBS1L-MYB RS4895441 gen polimorfizminin kliniğe etkisinin değerlendirilmesi
Giriş: Beta talasemiler en sık gözlenen otozomal resesif hastalıklardan biridir.Beta talasemilerde klinik özelliklerson derece değişkendir.Hastalık ciddiyetini belirleyen ana faktörler, hastalığa neden olan mutasyonun ...