ORCID "0000-0002-8084-7855" Makale Koleksiyonu için listeleme
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Spinal cerrahide gelecek vaat eden moleküler gelişmeler
Karaarslan, Numan; Yaşar Şirin, Duygu; Yılmaz, İbrahim; Özbek, Hanefi (Yüzüncü Yıl Üniversitesi Tıp Fakültesi, 2018)Amaç: Bu çalışmada, dünya genelinde yapılan çalışmalar içerisinde, omurga patolojisinin giderilmesinde araştırılan, moleküler düzeyde gerçekleştirilen hücresel bazlı hedef tedavilerin, sistematik olarak incelenip, konu ... -
A study of the effects of metformin, a biguanide derivative, on annulus fibrosus and nucleus pulposus cells
Kaya, Yasin Emre; Karaarslan, Numan; Yılmaz, İbrahim; Yaşar Şirin, Duygu; Akalan, Hande; Özbek, Hanefi (Turkish Neurosurgical Society, 2020)AIM: To investigate the effects of metformin, a drug used widely for the treatment of type 2 diabetes mellitus, on human primary cell cultures prepared from uninjured segment of disc material intervertebral disk tissues.MATERIAL ... -
A study on the effects of direct factor Xa inhibitors and direct thrombin inhibitors on human primary chondrocyte cultures
Kaya, Yasin Emre; Akalan, Hande; Yılmaz, İbrahim; Karaarslan, Numan; Yaşar Şirin, Duygu; Özbek, Hanefi; Ateş, Özkan (Namık Kemal University, 2019)Aim:This study investigates the effects of two direct factor Xa inhibitors, apixaban and rivaroxaban, and a direct thrombin inhibitor, dabigatran, on human primary chondrocytecultures. Materials and Methods:Monolayer ... -
The susceptibility to autoxidation of erythrocytes in diabetic mice: Effects of melatonin and pentoxifylline
Şekeroğlu, Mehmet Ramazan; Huyut, Zübeyir; Çokluk, Erdem; Özbek, Hanefi; Alp, Hamit Hakan (Wiley, 2017)Oxidative stress had a great importance in development of complications in diabetes. We investigated effects of melatonin and pentoxifylline in diabetic mice. Swiss albino mice (n=40) were divided into four groups: ... -
Systematic evaluation of promising clinical trials-gene silencing for the treatment of glioblastoma
Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Çalışkan, Tezcan; Topuk, Savaş; Yaşar Şirin, Duygu; Ateş, Özkan (Turkish Neurosurgical Society, 2019)AIM: To systematically investigate the role of artificial small interfering RNA (SiRNA) molecules in glioblastoma treatment and to give a detailed overview of the literature concerning studies performed in this field ...