ORCID "0000-0003-0352-1947" Makale Koleksiyonu için listeleme
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Isolation and culture of adult mouse vestibular nucleus neurons
Him, Aydın; Altuntaş, Serap; Öztürk, Gürkan; Erdoğan, Ender; Cengiz, Nurettin (TUBITAK Scientific & Technical Research Council Turkey, 2017)Background/aim: Isolated cell cultures are widely used to study neuronal properties due to their advantages. Although embryonic animals are preferred for culturing, their morphological or electrophysiological properties ... -
The levels of nitrite, nitrate and lipid peroxidation in diabetic mouse brain: The effect of melatonin and pentoxifylline
Yalçınkaya, Ahmet S.; Şekeroğlu, Mehmet Ramazan; Huyut, Zübeyir; Çokluk, Erdem; Özbek, Hanefi; Öztürk, Gürkan; Balahoroğlu, Ragıp (Taylor & Francis Ltd, 2022)Objective: This study investigated the relationship between diabetes (DM) and nitrite, nitrate and MDA levels and effect of melatonin and pentoxifylline. Methods: Sixty mice were randomly divided into four groups. Control: ... -
Mesenchymal stem cell-based COVID-19 therapy: Bioengineering perspectives
Karakaş, Nihal; Üçüncüoğlu, Süleyman; Uludağ, Damla; Karaoğlan, Birnur Sinem; Shah, Khalid; Öztürk, Gürkan (MDPI, 2022)The novel pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). Mesenchymal stem cells (MSCs) are currently utilized in clinics for pulmonary inflammatory ... -
Modulation of excitability of stellate neurons in the ventral cochlear nucleus of mice by atp-sensitive potassium channels
Bal, Ramazan; Öztürk, Gürkan; Önalan Etem, Ebru; Him, Aydın; Cengiz, Nurettin; Kuloǧlu, Tuncay; Tuzcu, Mehmet; Yıldırım, Caner; Tektemur, Ahmet (Springer, 2018)Major voltage-activated ionic channels of stellate cells in the ventral part of cochlear nucleus (CN) were largely characterized previously. However, it is not known if these cells are equipped with other ion channels apart ... -
Modulation of the excitability of stellate neurons in the ventral cochlear nucleus of mice by TRPM2 channels
Bal, Ramazan; Öztürk, Gürkan; Önalan Etem, Ebru; Eraslan, Ersen; Özaydın, Seda (Elsevier, 2020)Oxidative stress-induced Ca2+ permeable transient receptor potential melastatin 2 (TRPM2) channels are expressed at high levels in the brain, appear to link neuronal excitability to cellular metabolism, and are involved ... -
Neurons from human mesenchymal stem cells display both spontaneous and stimuli responsive activity
Karakaş, Nihal; Bay, Sadık; Türkel, Nezaket; Öztunç, Nurşah; Öncül, Merve; Bilgen, Hülya; Shah, Khalid; Şahin, Fikrettin; Öztürk, Gürkan (Public Library of Science, 2020)Mesenchymal stem cells have the ability to transdifferentiate into neurons and therefore one of the potential adult stem cell source for neuronal tissue regeneration applications and understanding neurodevelopmental ... -
A pooled RT-PCR testing strategy for more efficient Covid-19 pandemic management
Ayaz, Akif; Öztürk Demir, Aslı Güner; Öztürk, Gürkan; Koçak, Mehmet (Elsevier, 2022)Objectives: RT-PCR testing is indispensable in Covid-19 pandemic management. With the spread of the pandemic with emerging variants, the RT-PCR capacity is overburdened and new strategies and capabilities need to be ... -
Two distinct types of dying back axonal degeneration in vitro
Öztürk, Gürkan; Cengiz, Nurettin; Erdoğan, Ender; Him, Aydın; Oğuz Kaval, Elif; Yenidünya, E.; Ayşit, Neşe (Wiley, 2013)Aims: In many neurodegenerative diseases and following traumas, dying back degeneration is a common phenomenon that aggravates the pathology and may eventually lead to death of the affected neurone. We aimed to investigate ...