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A genetic mimic of cerebral palsy: Homozygous NFU1 mutation with marked intrafamilial phenotypic variation
(Elsevier, 2020)Background: Genetic defects in the NFU1, an iron-sulfur cluster scaffold protein coding gene, which is vital in the final stage of assembly for iron sulfur proteins, have been defined as multiple mitochondrial dysfunctions ... -
Genetic polymorphism in the serotonin transporter gene-linked polymorphic region and response to serotonin reuptake inhibitors in patients with premature ejaculation
(Hospital das Clínicas da Universidade de São Paulo, 2014)OBJECTIVES: Serotonin plays a central role in ejaculation and selective serotonin reuptake inhibitors have been successfully used to treat premature ejaculation. Here, we evaluated the relationship between a polymorphism ... -
Genetic polymorphisms in 15 STR loci in the Turkish population living in İstanbul province
(Nobelmedicus, 2022)Objective: Short tandem repeats (STRs) are short sequences of nucleotides that are repeated and distributed all over the genome. These polymorphisms enable investigation of the forensic, ancestral lineage and evolutionary ... -
A genetically specified connectomics approach applied to long-range feeding regulatory circuits
(Nature Publishing Group, 2014)Synaptic connectivity and molecular composition provide a blueprint for information processing in neural circuits. Detailed structural analysis of neural circuits requires nanometer resolution, which can be obtained with ... -
Genomic analysis reveals the biotechnological and industrial potential of levan producing halophilic extremophile, Halomonas smyrnensis AAD6T
(Springer International Publishing, 2015)Halomonas smyrnensis AAD6T is a gram negative, aerobic, and moderately halophilic bacterium, and is known to produce high levels of levan with many potential uses in foods, feeds, cosmetics, pharmaceutical and chemical ... -
Gentisic acid exerts neuroprotective effects in neurotoxin-induced Parkinson's disease model in zebrafish: Cross-talk between pathways related with neurodegeneration in the gut-brain axis
(2024)Given that global prevalence of Parkinson's disease (PD) is expected to rise over the next few decades, understanding the mechanisms and causes of PD is critical. With emphasis on gut-brain axis, we sought to assess the ... -
The geometrical modeling of aortic root complex
(2019)BACKGROUND: This study was designed to investigate the anatomical relationship of the different levels of aortic root. MATERIALS AND METHODS: The morphological features of the aortic root were examined using of 12 adult ... -
Gestational diabetes mellitus screening and outcomes
(Turkish-German Gynecological Education and Research Foundation, 2015)Objective: To verify the usefulness of the World Health Organization criteria for the diagnosis of gestational diabetes mellitus in pregnant women and its effectiveness in the prevention of maternal and neonatal adverse ... -
Giant aneurysm of the non-coronary sinus of valsalva
(Sociedade Brasileira de Cirurgia Cardiovascular, 2020)Aneurysms of the sinuses of Valsalva are defined as dilatation of the aortic root region between the aortic annulus and the sinotubular junction. Isolated aneurysms of the sinus of Valsalva are rare cardiovascular pathologies. ... -
Giant bladder calculi: A case report
(Urology and Nephrology Research Centre, 2015)Bladder calculi account for 5% of all urinary system calculi.(1) They are usually seen in older men and occur because of infravesical obstructions such as prostate hyperplasia, neurogenic bladder, urinary tract infection ... -
Giant epidermal cyst of the foot
(Srpsko Lekarsko Društvo, 2014)Introduction Epidermoid inclusion cysts are usually composed of epidermal elements implanted into the dermal layers. Patients are seen in the outpatient clinics with a mass. Most of the complaints are mechanical and cosmetic ... -
Giant left anterior descending coronary artery aneurysm in a patient with Behçet's disease
(Sociedade Brasileira de Cirurgia Cardiovascular: SBCCV, 2022)Coronary artery involvement is quite rare in the course of Behcet's disease. Complications secondary to coronary artery aneurysms, including rupture, dissection, and myocardial ischemia, may be fatal. In young patients ... -
Giant lipoma of the back affecting quality of life
(Elsevier, 2015)Lipomas are benign tumours composed of adipose tissue. They may be localized in almost all body parts and may be in a giant form. Some of these giant lipomas may transform malignity and cause problems in daily living and ... -
Giant mature adrenal cystic teratoma in an infant
(2013)Introduction: Teratomas are derived from embryonic tissues that are typically found in the gonadal and sacrococcygeal regions of adults and children. Primary teratomas in the retroperitoneum are very rare in infant and ... -
Giant pericardial tube roll aneurysm after the treatment of aortic interruption
(Thieme Medical Publishers, Inc., 2020)Various techniques have been described for the treatment of interrupted aortic arch pathology. Graft interposition, either autologous or synthetic, is included among these methods. In this article, we present the images ... -
Giant post-traumatic cyst after motorcycle injury: A case report with review of the pathogenesis.
(2013)Post-traumatic cysts of soft tissue usually occur at the junction of the subcutaneous fat and deep fascia, most often filled with serosanguinous fluid and lined with fibrous tissue. It appears as complication after severe ... -
Giant pulmonary pseudoaneurysm following balloon dilatation of the pulmonary artery to relieve pulmonary band
(Cambridge University Press, 2023)Pulmonary artery pseudoaneurysms are uncommon. They may occur secondary to trauma, infectious diseases, vasculitis syndromes, neoplasms, congenital diseases, and pulmonary hypertension. Due to increasing number of cardiac ... -
Gilteritinib (XOSPATA (R)) in Turkey: Early access program results
(Mattioli 1885, 2023)Background And Objectives: Gilteritinib (XOSPATA (R), Astellas) is a type I oral FLT3 inhibitor, a tyrosine kinase AXL inhibitor, involved in both c-Kit and FMS-like tyrosine kinase 3 (FLT3) resistance. In the phase 3 ... -
Gingipain injection affects intestinal oxidant-antioxidant status and alkaline phosphatase in overfed zebrafish
(Istanbul University Press, 2023)Objective: Porphyromonas gingivalis (P. gingivalis), a major periodontopathogen, is associated with overfeeding disorders, including metabolic syndrome. Gingipains are one of the most powerful endotoxins of P. gingivalis. ... -
Glass: Global lorlatinib for ALK(+) and ROS1(+) retrospective study: Real world data of 123 NSCLC patients
(Elsevier Ireland Ltd, 2020)Lorlatinib is a third-generation tyrosine-kinases inhibitor (TKI) targeting ALK/ROS1 fusions. The FDA has approved lorlatinib for TKI-pretreated ALK(+) NSCLC, while its approval for ROS1( + ) is still pending. Here we ...
