ORCID "0000-0001-9052-4411" Makale Koleksiyonu için listeleme
-
Are biological agents toxic to human chondrocytes and osteocytes?
İşyar, Mehmet; Bilir, Bülent; Yılmaz, İbrahim; Çakmak, Selami; Yaşar Şirin, Duygu; Yıldırım Güzelant, Aliye; Mahiroğulları, Mahir (BioMed Central, 2015)Purpose: The aim of the present study is to investigate the effects of biological agents (BAs) on human chondrocytes and osteocytes in vitro. Methods: Primary cell cultures obtained from gonarthrosis patients were divided ... -
Are chondrocytes damaged when rheumatologic inflammation is suppressed?
Yıldırım Güzelant, Aliye; İşyar, Mehmet; Yılmaz, İbrahim; Yaşar Şirin, Duygu; Çakmak, Selami; Mahiroğulları, Mahir (Taylor & Francis Inc, 2017)Aim: The use of biological agents (BAs) for treating diseases such as rheumatoid arthritis (RA), spondyloarthropathy, and systemic lupus erythematosus to reduce inflammation has been fruitful. Especially as part of the ... -
Are we economically efficient enough to ıncrease the potential of in vitro proliferation of osteoblasts by means of pharmacochemical agents?
İşyar, Mehmet; Gümüştaş, Seyit Ali; Yılmaz, İbrahim; Yaşar Şirin, Duygu; Tosun, Hacı Bayram; Mahiroğulları, Mahir (Bentham Open, 2016)Background: The aim of this study was to test the necessity of using expensive and unaccesible pharmacological-chemical agents in the proliferation of bone tissue cultures and in the induction of mineralized matrix formation ... -
Comparison of quadriceps muscle volume after unilateral total knee arthroplasty with and without tourniquet use
Güler, Olcay; Mahiroğulları, Mahir; İşyar, Mehmet; Pişkin, Ahmet; Yalçın, Sercan; Mutlu, Serhat; Şahin, Bünyamin (Springer, 2016)Determination of the effect of tourniquet use in total knee arthroplasty (TKA) on thigh and quadriceps muscle volume using magnetic resonance imaging (MRI). A total of 148 knees of 74 patients (mean age 66.5 +/- 4.8 years; ... -
Comparison of short-term results of intraarticular platelet-rich plasma (PRP) and hyaluronic acid treatments in early-stage gonarthrosis patients
Güler, Olcay; Mutlu, Serhat; İşyar, Mehmet; Şeker, Ali; Kayaalp, Mahmut Enes; Mahiroğulları, Mahir (Springer-Verlag, 2015)The present study aimed to compare short-term clinical outcomes between intraarticular platelet-rich plasma (PRP) and hyaluronic acid (HA) treatments in early-stage gonarthrosis patients. Data of gonarthrosis patients, who ... -
Efficacy of periarticular injection applied trough knee other than posterior capsule in simultaneous bilateral total knee arthroplasty
Güler, Olcay; Mutlu, Serhat; İşyar, Mehmet; Mutlu, Harun; Bülbül, Ahmet Murat; Mahiroğulları, Mahir (Reed Elsevier India, 2015)Background: We aimed to evaluate periarticular multimodal drug injection (PMDI) in bilateral total knee arthroplasty. Methods: In 154 knees of 77 patients, PMDI was administered intraoperatively through the regions other ... -
Evaluation of antibiotic alternatives used in orthopedic departments of 2 hospitals according to rational use of antibiotics
İşyar, Mehmet; Doğan, Mustafa; Gümüştaş, Seyit Ali; Yılmaz, İbrahim; Bilir, Bülent; Güler, Olcay; Saraçoğlu Varol, Gamze; Mahiroğulları, Mahir (Kare Yayıncılık ve İletişim Hizmetleri, 2016)Background: The present study is an analysis of appropriateness of antibiotics use for patients in whom infectious agent was detected. Data from patients in orthopedics and traumatology department of 2 hospitals in the ... -
Evaluation of neutrophil-to-lymphocyte ratio as a marker of inflammatory response in septic arthritis
Bilir, Bülent; İşyar, Mehmet; Yılmaz, İbrahim; Saraçoǧlu, Gamze Varol; Çakmak, Selami; Doǧan, Mustafa; Mahiroğulları, Mahir (Sage Publications, 2015)Is neutrophil-to-lymphocyte ratio high in patients with septic arthritis? Septic arthritis may lead to higher rates of morbidity or even mortality if not diagnosed on time. This study was planned to answer the question ... -
Evaluation of results of conservative therapy in patients with transient osteoporosis of hip
Güler, Olcay; İşyar, Mehmet; Mahiroğulları, Mahir; Özyürek, Selahattin; Çakmak, Selami; Mutlu, Serhat (ARSMB-KVBMG, 2015)The present study aimed to review the general characteristics of 18 cases diagnosed with transient osteoporosis of the hip (TOH) in our hospital within a 3-year period and to present their follow-up results after conservative ... -
Investigating the relationship between internal tibial torsion and medial collateral ligament injury in patients undergoing knee arthroscopy due to tears in the posterior one third of the medial meniscus
Güler, Olcay; İşyar, Mehmet; Karataş, Dilek; Örmeci, Tuğrul; Çerci, Halis; Mahiroğulları, Mahir (Elsevier Science Bv, 2016)Purpose: To evaluate the relationship between medial collateral ligament (MCL) injury and degree of internal tibial torsion in patients who had undergone arthroscopic resection due to tears in the posterior one third of ... -
Lomber perkutan endoskopik diskektomi erken dönem sonuçları
Uğraş, Sevda; Oltulu, İsmail; İşyar, Mehmet; Malkoç, Melih; Uğraş, Akın (Galenos, 2014)Amaç: Lomber perkütan endoskopik diskektomi erken dönem sonuçlarını tartışmak. Tarihçe: Lomber disk cerrahisinde minimal invazif diskektomiye izin veren endoskopik disk cerrahisi ülkemizde yeni kullanılan bir yöntemdir. ... -
Nail braces as an alternative treatment for ıngrown toenails: Results from a comparison with the winograd technique
Güler, Olcay; Tuna, Hamide; Mahiroğulları, Mahir; Erdil, Mehmet; Mutlu, Serhat; İşyar, Mehmet (Academic Press, 2015)Ingrown toenails are one of the most frequent nail disorders and can be treated with conservative or surgical approaches. Although discovered a long time ago, the available data are still very limited on the potential ... -
Ortopedik cerrah tirotoksik fırtınaya yakalanmamak için ne yapmalı?
Ekiz Bilir, Betül; Bilir, Bülent; İşyar, Mehmet; Tonbul, Ayşe Tuba; Öznam, Kadir; Yılmaz, İbrahim; Çakmak, Selami (2016)Amaç: Non iyonik kontrast maddeler gibi iyot içeren preparatların kullanıldığı görüntüleme tetkiklerinde, kas protein yıkımına neden olan travmalarda, kosta kırıklarında, pürülan artrit gibi enfektif olgularda, kalça ... -
Pelvik insidans elle mi, bilgisayar yardımlı mı ölçmeliyiz?
Oltulu, İsmail; Malkoç, Melih; İşyar, Mehmet; Yalçın, Sercan; Örmeci, Tuğrul; Uğraş, Akın (Türk Omurga Derneği, 2014)Amaç: El ile ya da bilgisayar yardımlı yapılan pelvik insidans ölçümlerinin birbirine üstünlüğünün karşılaştırılması. Hastalar ve Metod: Ayakta tüm spinal kolon anteroposterior ve lateral radyografileri olan otuz 20-40 yaş ... -
A practical way to prepare primer human chondrocyte culture
İşyar, Mehmet; Yılmaz, İbrahim; Şirin Yaşar, Duygu; Yalçın, Sercan; Güler, Olcay; Mahiroğulları, Mahir (Elsevier Science Bv, 2016)Biological cartilage repair is one of themost important targets for orthopedic surgeons currently. For this purpose, it is mandatory to know how to prepare a chondrocyte culture. In this study, our purpose was to introduce ... -
Prone versus supine position during surgery for supracondylar humeral fractures
Güler, Olcay; Mutlu, Serhat; İşyar, Mehmet; Mutlu, Harun; Çerci, Halis; Mahiroğulları, Mahir (Sage Publications INC, 2016)Purpose. To compare the supine versus prone position in closed reduction and percutaneous pinning for supracondylar humeral fractures in children in terms of patient characteristics and outcome. Methods. Records of 25 girls ... -
Radiological and clinical effect of prosthesis design in varus knees?
İşyar, Mehmet; Güler, Olcay; Çakmak, Selami; Kara, Adnan; Yalçın, Sercan; Mahiroğulları, Mahir (Reed Elsevier India Private, 2015)Purpose: The aim of the study is to investigate the efficacy of the prosthesis design used in total knee arthroplasty in patients with varus malalignment. Methods: After exclusion criteria we classified 90 patients underwent ... -
A retrospective analysis on the correlation between hip pain, physical examination findings, and alpha angle on MR images
Güler, Olcay; İşyar, Mehmet; Karataş, Dilek; Örmeci, Tuğrul; Çerçi, Halis; Mahiroğulları, Mahir (Biomed Central Ltd., 2016)Background: We aimed to search whether alpha angle, a radiological clue used in the diagnosis of femoroacetabular impingement, is correlated with the presence of hip pain, internal rotation angle, and impingement test ... -
Safety of bioabsorbable implants in vitro
İşyar, Mehmet; Yılmaz, İbrahim; Nusran, Gürdal; Güler, Olcay; Yalçın, Sercan; Mahiroğulları, Mahir (BioMed Central, 2015)Background: The aim of the present study was to investigate the safety of bioabsorbable plates and screws in humans. Methods: For this purpose, an implant system based on [poly(lactic-co-glycolic acids)(85:15)] was designed. ... -
Short-term results of robinson type 2B2 clavicular fractures treated conservatively or surgically
Malkoç, Melih; Korkmaz, Özgür; Bayram, Erhan; Örmeci, Tuğrul; İşyar, Mehmet; Yılmaz, Murat; Şeker, Ali (Slack Inc, 2016)The most frequently treated injuries, representing approximately 82% of all clavicular fractures, involve the midshaft clavicle. Historically, most acute displaced midshaft clavicular fractures were treated nonsurgically. ...