Ara
Toplam kayıt 69, listelenen: 51-60
Is there any prognostic significance in pleural involvement and/or effusion (Ple-I/E) in patients with ALK-positive NSCLC?
(Oxford University Press, 2019)
Background: ALK mutation occurs in approximately 3-5% of patients with NSCLC. At the baseline, Ple-I/E are more frequent in ALKþ patients with NSCLC. In the study, we aimed to evaluate characteristics of ALKþpatients who ...
Are pretreatment inflammation-based prognostic scores useful in predicting the outcomes of patients with ALK-positive NSCLC?
(Elsevier Science, 2019)
Background: Approximately 5% of all diagnosed non-small cell lung cancer (NSCLC) patients harbor a genetic rearrangement between the ALK and EML4 genes, representing a specific molecular and clinical subgroup (ALK+ NSCLC). ...
Lorlatinib in ALK- or ROS1-positive non-small cell lung cancer patients: Experience from an early access program in Turkey
(Elsevier Science, 2019)
Background: Lorlatinib, a third generation ALK and ROS1 inhibitor, is indicated for the treatment of patients with ALK+ metastatic NSCLC whose disease has progressed on crizotinib and at least one second-generation ALK ...
Artificial intelligence to assist better myeloma care, is it the time?
(Cıg Media Group, 2019)
Myeloma treatment made an enormous progress during the last decade. Armamentarium is grossly enlarging each year in the field of treatment. Parallel to the progress achieved to provide better care for myeloma patients, ...
The effect of improved metabolic risk factors and metformin therapy on circulating hepatokines in obese, insulin-resistant adolescents
(Karger, 2019)
Introduction: The molecular mechanisms underlying insulin resistance (IR) is complex and has not been fully elucidated yet. The experimental studies point out the role of liver-derived proteins, called hepatokines. Aims: ...
Clinical relevance of minor histocompatibility antigens
(Pergamon-Elsevier Science, 2019)
Objective: The minor histocompatibility antigens (MiHA) are epitopes composed of polymorphic essential peptides evoking alloimmune responses limited to a variety of human leukocyte antigen (HLA) alleles. These peptides are ...
A rare complication of hematopoietic stem cell transplantation: Kaposi sarcoma
(Pergamon-Elsevier Science, 2019)
Background: Kaposi sarcoma is a neoplasm characterized by mucocutaneous and visceral angioproliferations that requires infection with human herpes virus (HHV)-8 for its development. The iatrogenic variant is ...
Evaluation of brain MRI lesions in 381 girls with central precocious puberty
(Karger, 2019)
Central precocious puberty (CPP) in girls is a diagnosis increasingly made by the Pediatric Endocrinologists worldwide. Although it is most frequently of idiopathic origin, magnetic resonance imaging (MRI) of the brain is ...
Transient gonadal activation and infant growth velocity
(Karger, 2019)
Background: Hypothalamic-pituitary-gonadal axis is activated during the first 6 months of life, called as mini-puberty in which reproductive hormone levels may reach to adult levels. Although, our understanding of the ...