Browsing Biomedical Engineering by Department "İstanbul Medipol Üniversitesi, Rektörlük, Sağlık Bilim ve Teknolojileri Araştırma Enstitüsü"
Now showing items 1-20 of 25
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A 3-DoF robotic platform for the rehabilitation and assessment of reaction time and balance skills of MS patients
(Public Library of Science, 2023)The central nervous system (CNS) exploits anticipatory (APAs) and compensatory (CPAs) postural adjustments to maintain the balance. The postural adjustments comprising stability of the center of mass (CoM) and the pressure ... -
Antileishmanial activity of BNIPdaoct- and BNIPdanon-loaded emulsomes on leishmania infantum parasites
(Frontiers Media S.A., 2022)Among bisnaphthalimidopropyl (BNIP) derivatives, BNIPDaoct and BNIPDanon recently came forward with antileishmanial activities beyond the standard, commercialized antileishmanial therapies. However, high-level toxicity on ... -
A behavioral paradigm for cortical control of a robotic actuator by freely moving rats in a one-dimensional two-target reaching task
(Elsevier B.V., 2022)Background: Controlling the trajectory of a neuroprosthesis to reach distant targets is a commonly used brain-machine interface (BMI) task in primates and has not been available for rodents yet. New method: Here, we describe ... -
Bioconjugated beta-cyclodextrin-perfluorohexane nanocone clusters as functional nanoparticles for nanoparticle-mediated histotripsy
(American Chemical Society, 2022)Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs). NCCs can be obtained by simply mixing ... -
Centralized healthcare database for ensuring better healthcare: Are we lagging behind?
(Professional Medical Publications, 2024)Database is an organized set of large information gathered and stored electronically to be retrieved whenever required. The systematically stored information can be ... -
Characterization of FcγRIa (CD64) as a ligand molecule for site-specific IgG1 capture: A side-by-side comparison with protein a
(American Chemical Society, 2022)Fc γreceptors (FcγRs) are one of the structures that can initiate effector function for monoclonal antibodies. FcγRIa has the highest affinity toward IgG1-type monoclonal antibodies among all FcγRs. In this study, a ... -
Delivery of curcumin within emulsome nanoparticles enhances the anti-cancer activity in androgen-dependent prostate cancer cell
(Springer, 2023)Background: Curcumin, a dietary polyphenol isolated from turmeric, is a potent phytochemical possessing intrinsic anticancer activities against various cancer types including prostate cancer. However, low water solubility ... -
The effect of PEGylation components on drug release behavior of targeted reduced graphene oxide based drug delivery system
(2024)Reduced graphene oxide (rGO) is a restored, defect-free version of graphene oxide (GO) with regained graphene-like properties but encounters challenges in biomedical applications due to its low solubility. Especially for ... -
Experimental and computational investigation of clustering behavior of cyclodextrin-perfluorocarbon inclusion complexes as effective histotripsy agents
(American Chemical Society, 2022)Recently developed nanocones (NCs), which are inclusion complexes that are made up of cyclodextrins (CDs) and perfluorocarbons (PFCs), have shown promising results in nanoparticle-mediated histotripsy (NMH) applications ... -
Functionalized graphitic carbon nitrides for environmental and sensing applications
(Wiley, 2021)Graphitic carbon nitride (g-C3N4) is a metal-free semiconductor that has been widely regarded as a promising candidate for sustainable energy production or storage. In recent years, g-C3N4 has become the center of attention ... -
An integrated top-stage incubator and lens free holographic imaging system for culture monitoring applications
(SPIE, 2022)Lens free inline holographic microscopy was shown to be a potent approach for many applications relying on cellular imaging. Applications requiring a large field of view at moderate resolution are the ones that are most ... -
Investigation of optimum production conditions and the stability of β-cyclodextrin-perfluorocarbon nanocone clusters for histotripsy applications
(2024)Nanocone clusters (NCCs) have been developed as clusters with inclusion complexes of FDA-approved β-cyclodextrin (βCD) and perfluorocarbons (PFC) (i.e., perfluoropentane (PFP) and perfluorohexane (PFH)) and have shown ... -
Maskless lithography with holographic feedback for the fabrication of optical elements
(SPIE, 2022)Photolithography has become a powerful tool in the fabrication of micro-optical elements following the advancements in grayscale approaches. However, hitting tight design tolerance goals require precise control of all ... -
Mechanistic insight into the impact of a bivalent ligand on the structure and dynamics of a GPCR oligomer
(Elsevier B.V., 2022)Development of effective bivalent ligands has become the focus of intensive research toward modulation of G protein-coupled receptor (GPCR) oligomers, particularly in the field of GPCR pharmacology. Experimental studies ... -
Microwave-promoted continuous flow systems in nanoparticle synthesis-A perspective
(American Chemical Society, 2021)Microwave-promoted continuous flow systems have emerged as a game-changer in nanoparticle synthesis. Owing to the excellent compatibility between fast, sustainable microwave heating and one-step, efficient flow chemistry, ... -
Nanoparticle-mediated histotripsy using dual-frequency pulsing methods
(2024)Objective: Nanoparticle-mediated histotripsy (NMH) is a novel ablation method that combines nanoparticles as artificial cavitation nuclei with focused ultrasound pulsing to achieve targeted, non-invasive, and cell-selective ... -
Nanoplasmonic biosensors: Theory, structure, design, and review of recent applications
(Elsevier, 2021)Nanoplasmonic biosensing shows an immense potential to satisfy the needs of the global health industry -low-cost, fast, and portable automated systems; highly sensitive and real-time detection; multiplexing and miniaturization. ... -
Neuroprotective effects of curcumin-loaded emulsomes in a laser axotomy-induced CNS injury model
(Dove Medical Press Ltd, 2020)Purpose: Curcumin, a polyphenol isolated from the rhizomes of turmeric, holds great potential as a neuroprotective agent in addition to its anti-inflammatory and antioxidant characteristics. The poor bioavailability and ... -
A new strategy for direct solution electrospinning of phosphorylated poly(vinyl chloride)/polyethyleneimine blend in alcohol media
(Elsevier Ltd, 2023)Phosphorylated poly(vinyl chloride) (PPVC)/polyethyleneimine (PEI)-based nanofibers were produced via electrospinning in their blended solutions for the first time. For this purpose, PVC was partially converted into PVC-N3 ... -
Oxide glass formers extending persistent luminescence in Eu and Dy co-doped strontium aluminates
(Elsevier B.V., 2023)Recent work has shown that the incorporation of electrically charged, non-bridging oxygen (NBO) species into Eu and Dy co-doped Sr4Al14O25 (S4A7ED) crystal structure, in the form of BØ2O−, induces the clustering of divalent ...