Yazar "ElSayed, Mohamed E. H." için Biomedical Engineering listeleme
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Effects of droplet composition on nanodroplet-mediated histotripsy
Vlaisavljevich, Eli; Aydın, Ömer; Durmaz Yüksel, Yasemin; Lin, Kuang-Wei; Fowlkes, Brian; Xu, Zhen; ElSayed, Mohamed E. H. (Elsevier Science Inc, 2016)Nanodroplet-mediated histotripsy (NMH) is a targeted ablation technique combining histotripsy with nanodroplets that can be selectively delivered to tumor cells. In two previous studies, polymer-encapsulated perfluoropentane ... -
Formulation of acid-sensitive micelles for delivery of cabazitaxel into prostate cancer cells
Aydın, Ömer; Youssef, İbrahim; Durmaz Yüksel, Yasemin; Tiruchinapally, Gopinath; ElSayed, Mohamed E. H. (Amer Chemical Soc, 2016)We report the synthesis of an amphiphilic triblock copolymer composed of a hydrophilic polyethylene glycol) (PEG) block, a central poly(acrylic acid) (PAA) block, and a hydrophobic poly(methyl methacrylate) (PMMA) block ... -
Noninvasive ablation of prostate cancer spheroids using acoustically-activated nanodroplets
Aydın, Ömer; Vlaisavljevich, Eli; Yüksel Durmaz, Yasemin; Xu, Zhen; ElSayed, Mohamed E. H. (Amer Chemical Soc, 2016)We have developed acoustically activated nanodroplets (NDs) using an amphiphilic triblock copolymer, which self-assembles and encapsulates different perfluorocarbons including perfluoropentane (PFP) and perfluorohexane ... -
Synergistic inhibition of aggressive breast cancer cell migration and invasion by cytoplasmic delivery of anti-RhoC silencing RNA and presentation of EPPT1 peptide on "smart" particles
Kaushal, Neha; Tiruchinapally, Gopinath; Yüksel Durmaz, Yasemin; Bao, Liwei; Gilani, Rabia; Merajver, Sofia D.; ElSayed, Mohamed E. H. (Elsevier Science Bv, 2018)Overexpression of RhoC protein in breast cancer patients has been linked to increased cancer cell invasion, migration, and metastases. Suppressing RhoC expression in aggressive breast cancer cells using silencing RNA (siRNA) ...