Başlık için Biomedical Engineering listeleme
Toplam kayıt 117, listelenen: 95-114
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S-layer fusion protein as a tool functionalizing emulsomes and CurcuEmulsomes for antibody binding and targeting
(Elsevier, 2015)Selective targeting of tumor cells by nanoparticle-based drug delivery systems is highly desirable because it maximizes the drug concentration at the desired target while simultaneously protecting the surrounding healthy ... -
Sağlık teknolojisi değerlendirmede çok kriterli karar verme yaklaşımları üzerine bir derleme çalışması
(Düzce Üniversitesi, 2020)Sağlık sektöründe yer alan ilaçlar, tıbbi tedavi prosedürleri, tıbbı cihazlar, cerrahi teknikler ve sağlık sistemleri Sağlık Teknolojisi Değerlendirme (STD) kapsamında değerlendirilmektedir. Bu tip sağlık teknolojilerinin ... -
Scattering metal waveguide based speckle-enhanced prism spectrometry
(IEEE - Institute of Electrical and Electronics Engineers, Inc., 2020)We present an optical efficiency improved speckle spectrometer where a scattering metal wave-guide is utilized along with a conventional prism spectrometer. We conducted extensive tests on 25 different scatterers, involving ... -
Selective binding of pVTK peptide-and bisphosphonate-functionalized micelles to prostate cancer cells, osteoblasts, and osteoclasts
(Andover House, Inc., 2022)This report describes the development of functionalized polymeric micelles encapsulating a chemotherapeutic agent. The results indicate the ability to achieve selective uptake into different cell populations in metastatic ... -
SELEX against whole-cell bacteria resulted in lipopolysaccharide binding aptamers
(Elsevier B.V., 2022)Nucleic acid aptamers are target-specific oligonucleotides selected from combinatorial libraries through an iterative in vitro screening process known as Systemic Evolution of Ligands by Exponential Enrichment (SELEX). In ... -
Servikal omurga sonlu eleman modellemesinde, model geometrisinin biyomekanik parametrelere olan etkisi
(Institute of Electrical and Electronics Engineers, 2015)İnterspinus implantları, omurga stenosis ve faset artiritis gibi omurga patolojileri için kullanıldığı bilinir. Tasarımındaki ana düşünce spinos proseslere kuvvet uygulayarak birbirinden uzaklaştırmak ve klinisyenlerin ... -
A simple yet time-optimal and linear-space algorithm for shortest unique substring queries
(Elsevier, 2015)We revisit the problem of finding shortest unique substring (SUS) proposed recently by Pei et al. (2013) [12]. We propose an optimal O(n) time and space algorithm that can find an SUS for every location of a string of size ... -
Smart polymeric nanocarriers for miRNA delivery against triple negative breast cancer
(2024)The most typical malignancy in women is breast cancer. This translates to almost 2.3 million women who have been diagnosed with the illness, which, according to the World Health Organization (WHO), resulted in more than ... -
Soft segment length controls morphology of poly(ethylene oxide) based segmented poly(urethane-urea) copolymers in a binary solvent
(Elsevier Science Bv., 2017)It is known that morphology and structure-property behavior of poly(ethylene oxide) (PEO) based poly (urethane-urea) copolymers are affected by soft segment (SS) chain length. Here, a multi-scale computational study is ... -
Speckle-enhanced prism spectrometer
(IEEE Computer Society, 2019)We present an improved prism spectrometer with high wavelength range and spectral resolution. The device is an upgraded prism spectrometer that utilizes an additional scattering medium leading to a wavelength-dependent ... -
A speckle-enhanced prism spectrometer with high dynamic range
(IEEE Inst Electrical Electronics Engineers Inc, 2018)We present a novel spectrometer device offering a wide wavelength range and high resolution. The device builds upon a conventional prism spectrometer; however, an additional scattering medium is introduced to generate a ... -
Surgical and transcatheter pulmonary valve replacement in patients with repaired tetralogy of Fallot: Cardiac magnetic resonance imaging characteristics and morphology of right ventricular outflow tract
(Springer, 2023)BackgroundPulmonary valve replacement is recommended in patients with repaired tetralogy of Fallot based on cardiac magnetic resonance imaging (MRI) criteria. This procedure is performed by surgical or transcatheter ... -
Synergistic inhibition of aggressive breast cancer cell migration and invasion by cytoplasmic delivery of anti-RhoC silencing RNA and presentation of EPPT1 peptide on "smart" particles
(Elsevier Science Bv, 2018)Overexpression of RhoC protein in breast cancer patients has been linked to increased cancer cell invasion, migration, and metastases. Suppressing RhoC expression in aggressive breast cancer cells using silencing RNA (siRNA) ... -
Systematic evolution of ligands by exponential enrichment for aptamer selection
(Elsevier, 2018)Discovery of aptamers and developments in the field of nanotechnology has made a significant contribution to the field of biosensing. Nanomaterials with various physical, optic, and electronic properties have been ... -
Temperature and pH-dependent behaviors of mAb drugs: A case study for trastuzumab
(MDPI, 2022)The distortions in the high-order structure of therapeutic monoclonal antibodies (mAbs) under different environmental conditions acutely affect mAb stability, resulting in altered safety, efficacy, and shelf-life profiles. ... -
Total internal reflection holographic microscopy for cellular imaging
(SPIE, 2022)The study of interfacial structures is of utmost importance not only for various research fields such as cell biology and display systems but also their sub-disciplines. One of the traditional means of imaging buried ... -
Toward building hybrid biological/in silico neural networks for motor neuroprosthetic control
(Frontiers Research Foundation, 2015)In this article, we introduce the Bioinspired Neuroprosthetic Design Environment (BNDE) as a practical platform for the development of novel brain-machine interface (BMI) controllers, which are based on spiking model ... -
Truncation thresholds: A pair of spike detection thresholds computed using truncated probability distributions
(TUBITAK Scientific & Technical Research Council, 2017)We describe a method for computing a pair of spike detection thresholds, called 'truncation thresholds', using truncated probability distributions, for extracellular recordings. In existing methods the threshold is usually ... -
Using Johnson's SU distribution for modeling the background activity in extracellular neural recordings
(Institute of Electrical and Electronics Engineers Inc., 2021)Extracellular neural recordings obtained from awake behaving subjects through chronically implanted microelectrode arrays provide information about the functioning of the brain with sub-millisecond temporal resolution at ... -
Utilization of biased G protein-coupled receptor signaling towards development of safer and personalized therapeutics
(MDPI, 2019)G protein-coupled receptors (GPCRs) are involved in a wide variety of physiological processes. Therefore, approximately 40% of currently prescribed drugs have targeted this receptor family. Discovery of beta-arrestin ...
