dc.contributor.author | Yücel, Burak | |
dc.contributor.author | Gedikbaşı, Ali | |
dc.contributor.author | Dündar, Öznur | |
dc.contributor.author | Olgaç, Yusuf | |
dc.contributor.author | Yıldırım, Doǧukan | |
dc.contributor.author | Yıldırım, Gökhan Yetkin | |
dc.contributor.author | Polat, İbrahim | |
dc.date.accessioned | 10.07.201910:49:13 | |
dc.date.accessioned | 2019-07-10T20:02:39Z | |
dc.date.available | 10.07.201910:49:13 | |
dc.date.available | 2019-07-10T20:02:39Z | |
dc.date.issued | 2016 | en_US |
dc.identifier.citation | Yücel, B., Gedikbaşı, A., Dündar, Ö., Olgaç, Y., Yıldırım, D., Yıldırım, G. Y. ve Polat, İ. (2016). The utility of first trimester uterine artery Doppler, placental volume and PAPP-A levels alone and in combination to predict preeclampsia. Pregnancy Hypertension-An International Journal Of Womens Cardiovascular Health, 6(4), 269-273. https://dx.doi.org/10.1016/j.preghy.2016.04.007 | en_US |
dc.identifier.issn | 2210-7789 | |
dc.identifier.uri | https://dx.doi.org/10.1016/j.preghy.2016.04.007 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/3700 | |
dc.description | WOS: 000390825400006 | en_US |
dc.description | PubMed ID: 27939466 | en_US |
dc.description.abstract | In this study, we aimed to evaluate the detection of pre-eclampsia (PE) by integrating uterine artery Doppler, placental volume, and pregnancy-associated plasma protein A (PAPP-A) levels in the first trimester. We prospectively recruited 602 women that underwent 11-13 weeks' aneuploidy screening. The mean pulsatility index (PI) of the uterine arteries and the placental volume were measured by ultrasonography. Measurement of PAPP-A levels has been performed at the same day' of ultrasonographic examinations. The 90th percentile of uterine artery PI and the 10th percentile of placental volume and PAPP-A levels were used as cut-offs. Uterine artery PI, placental volume, and PAPP-A levels had similar sensitivities in predicting PE (53.66%, 63.41%, and 70.73%, respectively). Use of the parameters in combination had better sensitivity. If one parameter was positive, the sensitivity was 92.68% with 85.20% specificity. If at least two parameters were positive, the sensitivity was 85.37% with 98.89% specificity. In conclusion, the combination of increased PI of uterine artery with low placental volume and low PAPP-A levels in the first trimester achieved better results than either test alone in the prediction of PE. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Pregnancy-Associated Plasma Protein A (PAPP-A) | en_US |
dc.subject | Placental Volume | en_US |
dc.subject | Predict Preeclampsia | en_US |
dc.title | The utility of first trimester uterine artery Doppler, placental volume and PAPP-A levels alone and in combination to predict preeclampsia | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Pregnancy Hypertension-An International Journal Of Womens Cardiovascular Health | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı | en_US |
dc.identifier.volume | 6 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 269 | en_US |
dc.identifier.endpage | 273 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1016/j.preghy.2016.04.007 | en_US |
dc.identifier.wosquality | Q2 | en_US |
dc.identifier.scopusquality | Q2 | en_US |