dc.contributor.author | Atasoy, Deniz | |
dc.contributor.author | Sternson, Scott M. | |
dc.date.accessioned | 10.07.201910:49:13 | |
dc.date.accessioned | 2019-07-10T20:02:34Z | |
dc.date.available | 10.07.201910:49:13 | |
dc.date.available | 2019-07-10T20:02:34Z | |
dc.date.issued | 2018 | en_US |
dc.identifier.citation | Atasoy, D. ve Sternson, S. (2018). Chemogenetic tools for causal cellular and neuronal biology. Physiological Reviews, 98(1), 391-418. https://dx.doi.org/10.1152/physrev.00009.2017 | en_US |
dc.identifier.issn | 0031-9333 | |
dc.identifier.issn | 1522-1210 | |
dc.identifier.uri | https://dx.doi.org/10.1152/physrev.00009.2017 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/3679 | |
dc.description | WOS: 000424096200008 | en_US |
dc.description | PubMed ID: 29351511 | en_US |
dc.description.abstract | Chemogenetic technologies enable selective pharmacological control of specific cell populations. An increasing number of approaches have been developed that modulate different signaling pathways. Selective pharmacological control over G protein-coupled receptor signaling, ion channel conductances, protein association, protein stability, and small molecule targeting allows modulation of cellular processes in distinct cell types. Here, we review these chemogenetic technologies and instances of their applications in complex tissues in vivo and ex vivo. | en_US |
dc.description.sponsorship | European Molecular Biology Organization (EMBO) Installation Grant; Howard Hughes Medical Institute | en_US |
dc.description.sponsorship | D. Atasoy is supported by a European Molecular Biology Organization (EMBO) Installation Grant. S. M. Sternson is funded by the Howard Hughes Medical Institute. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | American Physiological Society | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Neuronal Biology | en_US |
dc.subject | Causal Cellular | en_US |
dc.subject | Chemogenetic Tools | en_US |
dc.title | Chemogenetic tools for causal cellular and neuronal biology | en_US |
dc.type | review | en_US |
dc.relation.ispartof | Physiological Reviews | en_US |
dc.department | İstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Fizyoloji Ana Bilim Dalı | en_US |
dc.department | İstanbul Medipol Üniversitesi, Rektörlük, Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER) | en_US |
dc.authorid | 0000-0002-3325-8820 | en_US |
dc.identifier.volume | 98 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 391 | en_US |
dc.identifier.endpage | 418 | en_US |
dc.relation.publicationcategory | Diğer | en_US |
dc.identifier.doi | 10.1152/physrev.00009.2017 | en_US |
dc.identifier.wosquality | Q1 | en_US |
dc.identifier.scopusquality | Q1 | en_US |