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The effects of smoking on genotoxic and histopathologic damage in exfoliated oral epithelial cells and the periodontium: A cross-sectional study
(NLM (Medline), 2023)
Smoking negatively affects the prognosis of periodontal disease by impairing tissue healing. While micronucleus is the most popular parameter for demonstrating DNA damage, inflammatory cell and vascular densities are the ...
Six miRNA expressions in the saliva of smokers and non-smokers with periodontal disease
(Wiley, 2023)
BackgroundIt has been stated that microRNA (miRNA) plays an important role in development, homeostasis, and immune functions, and abnormal miRNA expression may cause faster disease progression. ObjectiveThe aim of this ...
Could ofloxacin be an alternative to amoxicillin–Metronidazole as an adjunct to non-surgical periodontal therapy?
(AVES, 2023)
Objective: The best antibiotic approach for generalized periodontitis remains under debate. Therefore, in this study, the systemic administration of ofloxacin was compared against amoxi cillin–metronidazolein terms of ...
Salivary irisin level is higher and related with interleukin-6 in generalized periodontitis
(Springer Science and Business Media Deutschland GmbH, 2023)
Objectives: Irisin plays an important role in energy homeostasis, inflammation, glucose, and lipid metabolism, and it is shown to have relations with many inflammatory diseases. The aim of the study was to determine saliva ...
Parkinson’s disease alters the composition of subgingival microbiome
(Taylor and Francis Ltd., 2023)
Aim: The current study aimed to test the hypothesis that Parkinson’s disease exacerbates periodontitis by altering its microbiome. Materials and Methods: Clinical periodontal parameters were recorded. Subgingival samples ...
Sirtuin6 and Lipoxin A4 levels are decreased in severe periodontitis
(Springer, 2023)
Objective: Sirtuin6 plays an important role in the regulation of inflammation, homeostasis, and apoptosis, and it has anti-inflammatory effects on several diseases. Lipoxin A4 is a pro-resolving lipid mediator of inflammation ...
Parkinson's disease is positively associated with periodontal inflammation
(Wiley, 2023)
BackgroundParkinson's disease (PA) affects 1% of the global population above 60 years. PA pathogenesis involves severe neuroinflammation that impacts systemic and local inflammatory changes. We tested the hypothesis that ...