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Toplam kayıt 26, listelenen: 1-10
The role of St. John's Wort against formaldehyde toxicity induced by inhalation in rats
(Elsevier Ireland, 2017)
Formaldehyde (F) is a genotoxic substance that causes detrimental effects on the upper respiratory system. St. John’s wort (SJW) is a medicinal plant has antioxidative and anti-inflammatory properties. The present study ...
The effect of carnitine against acrylamide-induced toxicity in rat lung and liver tissues
(Elsevier Ireland Ltd, 2016)
Acrylamide (ACR) has the potential for cytotoxic and genotoxic effects by decreasing oxidative defense system and is known to be neurotoxic, hepatotoxic and carcinogenic to humans. Carnitine plays an important role in the ...
Investigation of genotoxicity risk and DNA repair capacity in breast cancer patients using anastrozole
(Kare Publishing, 2018)
OBJECTIVE: Breast cancer is the most common cancer in women worldwide and the incidence increases in postmenopausal women. Anastrozole is a non-steroidal (type II), third-generation aromatase inhibitor (AI) that is used ...
Comparison of inhaled and intraperitoneal formaldehyde toxicity in rats and the evaluation of the effects of melatonin
(Elsevier Ireland Ltd, 2016)
Formaldehyde (FA) is a genotoxic substance that causes deleterious effects on the nervous system, respiratory system, and reproductive system as a result of occupational exposure. FA is also classified as human carcinogen ...
A pilot study on effects of combination usage of curcumin and melatonin on cisplatin treatment
(Elsevier Ireland Ltd, 2016)
Cisplatin is an antitumor drug widely used in the treatmentof many malignant tumors. And also some studies show thatmelatonin and curcumin have antitumor activity via several mech-anisms including theirs in addition to ...
DNA damage in gasoline station workers caused by occupational exposure to petrol vapour in Turkey
(University of Istanbul, 2016)
The refueling of vehicles is a major source of volatile organic compounds generated by used and evaporated fuel. Gasoline workers are directly exposed to various fuel products via many routes in the ambient air. The aim ...
Evaluation of the in vivo preclinical toxicity of targeted nanoparticles
(Taylor and Francis, 2021)
Drug delivery systems include nanoparticles (NPs), nanoemulsions, nanosuspensions, nanoliposomes, niosomes, dendrimers, fullerene, carbon nanotubes, nanogels, polymeric micelles, and solid lipid NPs. Although the drug-based ...
The influence of different extraction methods/solvents on composition, biological activities and ADMET predictions of phenolics in tribulus terrestris
(Instituto de Tecnologia do Parana, 2021)
Tribulus terrestris is a plant that has medical importance in treating diseases such as cancer, urinary tract infections, kidney stones, rheumatism, and hypertension. The aim of this study is to examine the effects of ...
Biological activities of the Ornithogalum orthophyllum and its in silico ADMET profile
(TMR Publishing Group, 2021)
Background: The bulbs and aerial parts of Ornithogalum are used in Turkey both as food and to treat various ailments, and some of its medical applications are well known. However, the biological activities of Ornithogalum ...