Ara
Toplam kayıt 4, listelenen: 1-4
Benzotriazole-oxadiazole hybrid compounds: Synthesis, anticancer activity, molecular docking and ADME profiling studies
(Elsevier B.V., 2022)
Herein the designed novel benzotriazole-oxadiazole hybrid compounds were synthesized using both conventional method and ultrasound sonication (US) as an environmentally friendly method. It was observed that the US method ...
Pyridine-substituted thiazolylphenol derivatives: Synthesis, modeling studies, aromatase inhibition, and antiproliferative activity evaluation
(Wiley-VCH Verlag, 2018)
Drugs used in breast cancer treatments target the suppression of estrogen biosynthesis. During this suppression, the main goal is to inhibit the aromatase enzyme that is responsible for the cyclization and structuring of ...
Synthesis and anticancer activity of some 1,2,3-trisubstituted pyrazinobenzimidazole derivatives
(Taylor & Francis, 2014)
The synthesis of some new pyrazino[1,2-a]benzimidazole derivatives and investigation of their anticancer activities were aimed in this work. Thus, 2-acetylbenzimidazole was reacted with appropriate alpha-bromoacetophenones ...
Design, synthesis and biological evaluation of novel tetralone/indanone containing thiosemicarbazone derivatives with selective COX-2 inhibition as anticancer agents
(Elsevier B.V., 2023)
A series of novel tetralone/indanone moiety-bearing thiosemicarbazone derivatives were synthesized and evaluated for their biological activities. The structural elucidations of the compounds were performed by IR spectroscopy, ...