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Toplam kayıt 11, listelenen: 1-10
Discovery of novel potent human chondrosarcoma (SW1353) inhibitors: 4-(2/3/4-pyridyl)thiazole 2-acetamide derivatives
(Elsevier B.V., 2023)
Chondrosarcoma is the most common cartilage sarcoma among adult patients. It is mainly observed after the degradation of chondrocytes in the case of cell stress. Unfortunately, the mortality among patients is high as a ...
In Vitro Antiviral Evaluations of Coldmix®: An Essential Oil Blend against SARS-CoV-2
(NLM (Medline), 2023)
Coldmix® is a commercially available Eucalyptus aetheroleum and, Abies aetheroleum blend for medicinal applications. In this present study, the in vitro antiviral potential of Coldmix®, and its major constituents 1,8-cineole ...
Novel benzydamine hydrochloride and chlorhexidine gluconate loaded bioadhesive films for local treatment of buccal infections
(Editions de Sante, 2023)
Benzydamine hydrochloride (BZD), chlorhexidine gluconate (CHG) or their combination are frequently used as liquid dosage forms for the local treatment of buccal fungal and bacterial infections. However, the short residence ...
Design, synthesis and biological evaluation of novel tetralone/indanone containing thiosemicarbazone derivatives with selective COX-2 inhibition as anticancer agents
(Elsevier B.V., 2023)
A series of novel tetralone/indanone moiety-bearing thiosemicarbazone derivatives were synthesized and evaluated for their biological activities. The structural elucidations of the compounds were performed by IR spectroscopy, ...
In vitro and in silico evaluation of ACE2 and LOX inhibitory activity of origanum essential oils and carvacrol
(Georg Thieme Verlag KG, 2023)
Origanum spp. are used both for culinary purposes and for their biological activities. In this study, commercial Origanum majorana, Origanum minutiflorum, Origanum vulgare, and Origanum onites essential oils and their ...
Biological activities of the natural coumarins from apiaceae plants
(ACG Publications, 2023)
Nineteen natural coumarins; badrakemin (1), colladonin (2), 14'-acetoxybadrakemin (3), anatolicin (4), 14'-hydroxycolladonin (5), badrakemone (6), karatavicinol (7), 14'-acetoxybadrakemone (8), 14'-acetoxycolladonin (9), ...
In vitro cytotoxicity evaluation and phytochemical analysis of Ajuga reptans L. extracts
(Marmara University, 2023)
The aim of this study was to evaluate phytochemical composition of Ajuga reptans L. (Lamiaceae) aerial parts (separately flower and leaf) methanol, aqueous-methanolic extracts, and their cytotoxic activities. The phytochemical ...
Novel sprayable thermosensitive benzydamine hydrogels for topical application: Development, characterization, and in vitro biological activities
(Springer Science and Business Media Deutschland GmbH, 2023)
Benzydamine hydrochloride (BZD) having analgesic, anesthetic, and anti-inflammatory effects is used orally or topically in the treatment of disorders such as joint inflammation and muscle pain. Within the scope of this ...
Comparison of In vitro Anti-inflammatory, COX-1/COX-2 and LOX inhibitory activities of Malva sylvestris L. leaves and flowers extract
(Georg Thieme Verlag KG, 2023)
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In vitro anti-inflammatory and anticancer evaluation of mentha spicata l. and matricaria chamomilla l. essential oils
(American Chemical Society, 2023)
Spearmint, Mentha spicata L., and the German chamomile, Matricaria chamomilla L., preparations are used against inflammatory conditions traditionally and in modern medicinal applications. This present study aimed to evaluate ...