Ara
Toplam kayıt 28, listelenen: 11-20
Synthesis, structure elucidation and determination of acid dissociation constant, tautomerism of pyrido [1,2-a] benzimidazole-2,4-dione
(University of Istanbul, 2016)
The first starting material, 1H-2-acetylbenzimidazole, 4, was synthesized by o-phenylenediamine, 1, and lactic acid solution, 2, in hydrochloric acid medium on the first step than, oxidation reaction was performed by CrO3 ...
Synthesis of novel 3, 5, 6-trisubstituted triazine derivatives and their biological activity evaluation as potential antitumor and anti-inflammatory agents
(University of Istanbul, 2016)
In this study, new 3, 5, 6-trisubstituted 1, 2, 4-triazine derivatives (1-9) were synthesized and their structures were determined by using NMR, IR and Mass spectroscopic methods. In vitro antitumor activities against MCF-7 ...
DNA damage in gasoline station workers caused by occupational exposure to petrol vapour in Turkey
(University of Istanbul, 2016)
The refueling of vehicles is a major source of volatile organic compounds generated by used and evaporated fuel. Gasoline workers are directly exposed to various fuel products via many routes in the ambient air. The aim ...
Synthesis and antimicrobial activity evaluation of novel nitrofuranthiazoles
(University of Istanbul, 2016)
In this work, six novel 4-aryl-2-[2-((5-nitrofuran-2-yl)methylene)hydrazinyl] thiazole derivatives (2a-f) were synthesized starting from 5-nitro-2-furaldehyde diacetate by using Hantzsch thiazole synthesis. The antimicrobial ...
Determination and evaluation of acidity constants of some imidazole and thiazole linked acetamide compounds
(Anadolu University, 2016)
In this work, the effect of substituents on the acidity constants of some acetamide derivatives was investigated. The acidity constants of nine acetamide derivatives were determined at 25 °C using a UV spectrophotometric ...
Development and in vitro evaluation of theophylline loaded matrix tablets prepared with direct compression
(Association of Pharmaceutical Teachers of India, 2016)
The objectives of the present study are to develop novel sustained release matrix tablets of theophylline and to evaluate release properties and kinetic behaviour of these tablets. The formulations have been prepared in ...
Platinum(II)-thiosemicarbazone drugs override the cell resistance due to glutathione; assessment of their activity against human adenocarcinoma cells
(Taylor & Francis Ltd, 2016)
New platinum(II) compounds of the thiosemicarbazone 1-(1H-Benzimidazol-2-yl)ethan-1-one thiosemicarbazone (BzimetTSCH), [Pt(BzimetTSCH)Cl]center dot 2H(2)O (1) and [Pt(BzimetTSCH)(tpp)]Cl center dot H2O center dot MeCN (2) ...
Occurrence of fumonisins B1 and B2 in homemade medicinal plants: Exposure assessment in Northern Turkey
(Akademiai Kiado Rt., 2016)
This study was conducted to determine the recent level of contamination with Fumonisin B1 (FB1) and Fumonisin B2 (FB2) in major medicinal plants and to assess consumer exposure in northern Turkey. FB1 and FB2 were investigated ...
Evaluation of in vitro antiprotozoal activity of Ajuga laxmannii and its secondary metabolites
(Taylor & Francis Ltd, 2016)
Context Some Ajuga L. (Lamiaceae) species are traditionally used for the treatment of malaria, as well as fever, which is a common symptom of many parasitic diseases.Objective In the continuation of our studies on the ...
Two different approaches for oral administration of voriconazole loaded formulations: Electrospun fibers versus beta-cyclodextrin complexes
(MDPI, 2016)
In this work, a comparison between two different preparation methods for the improvement of dissolution rate of an antifungal agent is presented. Poly(epsilon-caprolactone) (PCL) electrospun fibers and beta-cyclodextrin ...