Kurum Yazarı "Güzel, Mustafa" Eczacılık Fakültesi İçin Listeleme
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Cytotoxic activity and docking studies of 2-arenoxybenzaldehyde N-acyl hydrazone and 1,3,4-oxadiazole derivatives against various cancer cell lines
Aydın, Esranur; Şentürk, Ahmet Mesut; Başpınar Küçük, Hatice; Güzel, Mustafa (MDPI, 2022)To understand whether previously synthesized novel hydrazone and oxadiazole derivatives have promising anticancer effects, docking studies and in vitro toxicity assays were performed on A-549, MDA-MB-231, and PC-3 cell ... -
An economical and practical procedure of favipiravir synthesis for the treatment of Covid-19
Karataş, Hacer; Hanashalshahaby, Essam Hamied Ahmed; Çatal, Ünal; Bütün, Yaşar Enes; Kurt, Elif; Gürsel, Şahin; Kaya, Adil; Güzel, Mustafa (Springer Science and Business Media Deutschland GmbH, 2023)Favipiravir is a wide-spectrum antiviral generic drug that has received large attention during the recent COVID-19 pandemic. While there are synthetic strategies for favipiravir synthesis, economical procedures could ... -
Effect of trastuzumab and lonidamine-loaded lipid nanoparticles (lnp) on her2+ breast cancer
Zurnacı, Fatma Özlem; Özdatlı Kurtuluş, Şükran; Şengel Türk, Ceyda Tuba; Hasçiçek, Canan; Güzel, Mustafa (2024)Our study involves inhibition of glycolysis and inhibition of the HER2 pathway, which is highly expressed in many types of cancer. Decreased survival, negative metastasis, and induced apoptosis are expected due to the ...