Browsing Eczacılık Fakültesi by ORCID "0000-0003-2493-9664"
Now showing items 1-6 of 6
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Chemical composition and in vitro mutagenic, antioxidant and anti-inflammatory activities of Lavandula angustifolia Mill. essential oil from Turkey
Omurtag Özgen, Pınar Sinem; Biltekin, Sevde Nur; İduğ, Tuğba; Macit, Çağlar; Ayran, İrem; Çelik, Sadiye Ayşe; Kültür, Şükran; Kan, Yüksel; Omurtag, Gülden Zehra (Marmara University, 2022)The essential oil obtained from Lavandula angustifolia Mill. (Lavander) has many pharmacological effects, including antioxidant, antifungal, antibacterial and carminative effects. Lavandula angustifolia essential oil (LEO) ... -
Dual-drug conjugated glyco-nanoassemblies for tumor-triggered targeting and synergistic cancer therapy
Gençoğlu Katmerlikaya, Tuğba; Dağ, Aydan; Omurtag Özgen, Pınar Sinem; Çetin Ersen, Büşra (American Chemical Society, 2022)Drug-conjugated nanoassemblies potentiate the efficiency of anticancer drugs through the advantages of high drug-loading capacity and passive/active targeting ability in cancer therapy. This study describes the synthesis ... -
Glyconanoparticles for targeted tumor therapy of platinum anticancer drug
Dağ, Aydan; Omurtag Özgen, Pınar Sinem; Atasoy, Sezen (American Chemical Society, 2019)An important requirement to decrease the side effects of chemotherapy drugs is to develop nanocarriers with precise biological functions. In this work, a set of glyconanoparticles was prepared via self-assembly of amphiphilic ... -
Glycopolymer decorated multiwalled carbon nanotubes for dual targeted breast cancer therapy
Omurtag Özgen, Pınar Sinem; Atasoy, Sezen; Zengin Kurt, Belma; Durmuş, Zehra; Yiğit, Gülşah; Dağ, Aydan (Royal Society of Chemistry, 2020)Carbon-based nanomaterials (CNMs) have attracted great attention in biomedical applications such as cancer imaging and therapy. CNMs, which are currently used in a wide range of applications, suffer from drawbacks of ... -
Increasing the biocompatibility of graphene-based hybrid nanostructures with glycopolymer
Dağ, Aydan; Omurtag Özgen, Pınar Sinem; Zengin Kurt, Belma; Durmuş, Zehra (Scientific Technical Research Council Turkey-TUBITAK, 2022)Hybrid nanostructures decorated with glycopolymers are appropriate for biomedical applications. In this paper, the results are obtained from nanographene (NG) decorated with glycoblock copolymer to increase their potential ... -
Phthalocyanine-conjugated glyconanoparticles for chemo-photodynamic combination therapy
Daǧ, Aydan; Çakılkaya, Eda; Omurtag Özgen, Pınar Sinem; Atasoy, Sezen; Yiğit Erdem, Gülşah; Çetin, Büşra; Çavuş Kokuroǧlu, Aytaç; Gürek, Ayşe Gül (NLM (Medline), 2021)Combination cancer therapy based on multifunctional nanomaterials has attracted great attention. The present work focuses on the preparation of the glycopolymeric nanoparticle, which contains a photosensitizer (zinc(II)p ...