Browsing Eczacılık Fakültesi by Author "Tay, Naime Funda"
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Determination and evaluation of acidity constants of some imidazole and thiazole linked acetamide compounds
Tay, Naime Funda; Duran, Murat; İspir, Cihan; Demirayak, Şeref (Anadolu University, 2016)In this work, the effect of substituents on the acidity constants of some acetamide derivatives was investigated. The acidity constants of nine acetamide derivatives were determined at 25 °C using a UV spectrophotometric ... -
Synthesis of some N-[4-(benzothiazole-2yl)phenyl]-2-aryloxyacetamide derivatives and their anticancer activities
Tay, Naime Funda; Yurttaş, Leyla; Demirayak, Şeref (Informa Healtcare, 2012)In this study, some N-[4-(Benzothiazole-2-yl)phenyl]-2-aryloxyacetamide derivatives were prepared by reacting N-[4-(benzothiazole-2yl)phenyl]-2-chloroacetamide and different substituent phenol or thiophenol derivatives. ... -
Synthesis, antimicrobial activity and modeling studies of thiazoles bearing pyridyl and triazolyl scaffolds
Tay, Naime Funda; Berk, Barkın; Duran, Murat; Kayagil, İsmail; Yurttaş, Leyla; Biltekin Kaleli, Sevde Nur; Yamaç, Mustafa; Karaduman, Ayşe Betül; Demirayak, Şeref (Walter de Gruyter GmbH, 2022)In this study, novel 4-(5-((2/3/4-substituted benzyl)thio)-4-(4-substituted phenyl)-4H-1,2,4-triazol-3-yl)-2-(pyridin-3/4-yl)thiazoles were synthesized following a multi-step synthetic procedure. All the compounds were ... -
Synthesis, antimicrobial and antioxidant activities of pyridyl substituted thiazolyl triazole derivatives
Tay, Naime Funda; Duran, Murat; Kayagil, İsmail; Yurttaş, Leyla; Göger, Gamze; Göğer, Fatih; Demirci, Fatih; Demirayak, Şeref (Universidade de São Paulo, 2022)In this present study, 63 different 5-[4-methyl-2-(pyridin-3/4-yl)thiazole-5-yl]-4-substituted-3-substituted benzylthio-4H-1,2,4-triazole derivatives were synthesized, and evaluated for their in vitro antimicrobial activity ... -
Synthesis, structure elucidation and determination of acid dissociation constant, tautomerism of pyrido [1,2-a] benzimidazole-2,4-dione
Kayağil, İsmail; Tay, Naime Funda; Konak, Hüseyin Yaşar; İspir, Cihan; Demirayak, Şeref (University of Istanbul, 2016)The first starting material, 1H-2-acetylbenzimidazole, 4, was synthesized by o-phenylenediamine, 1, and lactic acid solution, 2, in hydrochloric acid medium on the first step than, oxidation reaction was performed by CrO3 ...