Yazar "Omurtag Özgen, Pınar Sinem" için Eczacılık Fakültesi listeleme
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Antibacterial properties of carvacrol against antibiotic-resistant bacteria, enteric bacteria, and oral pathogens
Hoş, Ayşegül; Omurtag Özgen, Pınar Sinem; İnci, Ayşe; Avcı, Buse; Ceylan, Ceyda (Marmara University, 2023)The present study investigated the antibacterial activity of carvacrol against Vancomycin-Resistant Enterococci (VRE), Carbapenem-Resistant Enterobacteriaceae (CRE), Methicillin-Resistant Staphylococcus aureus (MRSA), ... -
Chemical composition and in vitro mutagenic, antioxidant and anti-inflammatory activities of Lavandula angustifolia Mill. essential oil from Turkey
Omurtag Özgen, Pınar Sinem; Biltekin, Sevde Nur; İduğ, Tuğba; Macit, Çağlar; Ayran, İrem; Çelik, Sadiye Ayşe; Kültür, Şükran; Kan, Yüksel; Omurtag, Gülden Zehra (Marmara University, 2022)The essential oil obtained from Lavandula angustifolia Mill. (Lavander) has many pharmacological effects, including antioxidant, antifungal, antibacterial and carminative effects. Lavandula angustifolia essential oil (LEO) ... -
Dual-drug conjugated glyco-nanoassemblies for tumor-triggered targeting and synergistic cancer therapy
Gençoğlu Katmerlikaya, Tuğba; Dağ, Aydan; Omurtag Özgen, Pınar Sinem; Çetin Ersen, Büşra (American Chemical Society, 2022)Drug-conjugated nanoassemblies potentiate the efficiency of anticancer drugs through the advantages of high drug-loading capacity and passive/active targeting ability in cancer therapy. This study describes the synthesis ... -
Glyconanoparticles for targeted tumor therapy of platinum anticancer drug
Dağ, Aydan; Omurtag Özgen, Pınar Sinem; Atasoy, Sezen (American Chemical Society, 2019)An important requirement to decrease the side effects of chemotherapy drugs is to develop nanocarriers with precise biological functions. In this work, a set of glyconanoparticles was prepared via self-assembly of amphiphilic ... -
Glycopolymer decorated multiwalled carbon nanotubes for dual targeted breast cancer therapy
Omurtag Özgen, Pınar Sinem; Atasoy, Sezen; Zengin Kurt, Belma; Durmuş, Zehra; Yiğit, Gülşah; Dağ, Aydan (Royal Society of Chemistry, 2020)Carbon-based nanomaterials (CNMs) have attracted great attention in biomedical applications such as cancer imaging and therapy. CNMs, which are currently used in a wide range of applications, suffer from drawbacks of ... -
Importance and review of drug metabolite synthesis
Şahin, Zafer; Omurtag Özgen, Pınar Sinem; Rollas, Sevim (Istanbul University, 2023)Phase I and Phase II metabolic reactions are involved in the pharmacokinetic properties of drugs after administration. These reactions mainly aim to make drugs more polar and eliminate them safely. However, some of these ... -
Increasing the biocompatibility of graphene-based hybrid nanostructures with glycopolymer
Dağ, Aydan; Omurtag Özgen, Pınar Sinem; Zengin Kurt, Belma; Durmuş, Zehra (Scientific Technical Research Council Turkey-TUBITAK, 2022)Hybrid nanostructures decorated with glycopolymers are appropriate for biomedical applications. In this paper, the results are obtained from nanographene (NG) decorated with glycoblock copolymer to increase their potential ... -
Non-covalent functionalization of single walled carbon nanotubes with pyrene pendant polyester: A DFT supported study
Omurtag Özgen, Pınar Sinem; Durmaz, Hakan; Parlak, Cemal; Alver, Özgür; Bağlayan, Özge (Elsevier, 2020)Non-covalent attachment onto single-walled carbon nanotubes (SWCNTs) by protecting nanotubes' intrinsic properties has an important role in development of hybrid composite materials. Herein, we present non-covalent ... -
Phthalocyanine-conjugated glyconanoparticles for chemo-photodynamic combination therapy
Daǧ, Aydan; Çakılkaya, Eda; Omurtag Özgen, Pınar Sinem; Atasoy, Sezen; Yiğit Erdem, Gülşah; Çetin, Büşra; Çavuş Kokuroǧlu, Aytaç; Gürek, Ayşe Gül (NLM (Medline), 2021)Combination cancer therapy based on multifunctional nanomaterials has attracted great attention. The present work focuses on the preparation of the glycopolymeric nanoparticle, which contains a photosensitizer (zinc(II)p ...