Browsing Eczacılık Fakültesi by Author "Karadağ, Ayşe Esra"
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ACE2 and LOX enzyme inhibitions of different lavender essential oils and major components linalool and camphor
Biltekin, Sevde Nur; Karadağ, Ayşe Esra; Demirci, Betül; Demirci, Fatih (American Chemical Society, 2022)In this present study, Lavandula angustifolia, Lavandula stoechas, and Lavandula x heterophylla essential oils and their main compounds linalool and camphor were evaluated in vitro for lipoxygenase enzyme (LOX) and for ... -
An alternative approach wound healing field with polypodium vulgare
Batur, Şebnem; Ayla, Şule; Şakul, Ayşe Arzu; Okur, Mehmet Evren; Karadağ, Ayşe Esra; Daylan, Benay; Özdemir, Ekrem Musa; Kepil, Nuray; Günal, Mehmet Yalçın (Logos Medical Publishing, 2020)Objective: In this study, we examined the effects of Polypodium vulgare L. (Polypodiaceae) as a candidate to be used for wound healing scarred area. We investigated the antibacterial, and antioxidant activity of P. Vulgare ... -
Anti-inflammatory, analgesic and in vivo-in vitro wound healing potential of the Phlomis rigida Labill. extract
Okur, Mehmet Evren; Karadağ, Ayşe Esra; Özhan, Yağmur; Sipahi, Hande; Ayla, Şule; Daylan, Benay; Kültür, Şükran; Demirci, Betül; Demirci, Fatih (Elsevier Ireland Ltd, 2021)Ethnopharmacological relevance: The preparations of Phlomis aerial parts are used traditionally in Anatolia for wound healing and in inflammatory disorders. Methods: For the identification of the active fraction, the air ... -
Antibacterial evaluation of elettaria cardamomum (L.) Maton, Lavandula angustifolia mill. and salvia fruticosa mill. essential oil combinations in mouthwash preparations
Karadağ, Ayşe Esra; İpekçi, Esra; Yağcılar, Ayşe Pınar; Demirbolat, İlker; Kartal, Murat; Siafaka, Panoraia I.; Üstündaǧ Okur, Neslihan (Badebio Biotechnololgy Ltd, 2020)The aim of this present study was to evalute Elettaria cardamomum (L.) Maton., Lavandula angustifolia Mill. and Salvia fruticosa Mill. essential oils in mouthwashes formulated with different combinations such as 0.1/0.25/0.1; ... -
Antimicrobial, anticholinesterase evaluation and chemical characterization of essential oil Phlomis kurdica Rech. fil. Growing in Turkey
Karadağ, Ayşe Esra; Demirci, Betül; Kültür, Şükran; Demirci, Fatih; Başer, K. Hüsnü Can (Taylor and Francis Inc., 2020)The Phlomis kurdica Rech.fil. (Lamiaceae) essential oil was investigated for its chemical constituents and in vitro biological activities. Volatile components were characterized, antimicrobial and anticholinesterase ... -
Antioxidant activity and anti-cancer effects of bilberry (vaccinium myrtillus l.) fruit extract on gastric cancer, ags cell line
Karakaş, Nihal; Okur, Mehmet Evren; Sağır, Tuğba; Uludağ, Damla; Polat, Derya Çiçek; Karadağ, Ayşe Esra (Ankara University, 2022)Objective: Vaccinium myrtillus L. fruits are consumed as food. This research was aimed to evaluate V. myrtillus methanol extract antioxidant and cytotoxic activities and determine its anti-cancer potential to further study ... -
Antioxidant activity of blackthorn (Prunus spinosa L.) fruit extract and cytotoxic effects on various cancer cell lines
Karakaş, Nihal; Okur, Mehmet Evren; Öztürk, İrem; Ayla, Şule; Karadağ, Ayşe Esra; Polat, Derya Çiçek (Logos Medical Publishing, 2019)Objective: Blackthorn (Prunus spinosa L. (Rosaceae) is a shrup whose fruits are consumed as food in Turkey. This study was aimed to evaluate antioxidant activity of methanol extract of P. spinosa and its cytotoxic effects ... -
Arctium minus metanol ekstresinin çeşitli kanser hücre hatları üzerinde sitotoksik etkileri
Sayın Şakul, Ayşe Arzu; Yozgat Byrne, Yasemin; Karadağ, Ayşe Esra; Altınalan, Ebrar; Çimen, Şeyma; Okur, Mehmet Evren (Ankara Üniversitesi, 2022)Amaç: Bu çalışmada Arctium minus (Hill) Bernh. ssp. minus’un toprak üstü kısımlarından elde edilen metanol ekstresinin kanser hücre hatları üzerindeki sitotoksik etkilerinin değerlendirilmesi amaçlanmıştır. Gereç ve ... -
Bioautography for evaluation of several Lavandula L. and origanum species antimicrobial and antioxidant activity
Karavuş, Şule Nur; Çaşkurlu, Ayşegül; Karadağ, Ayşe Esra; Demirci, Fatih (Istanbul Medipol University, 2023)In the search of bioactive natural compounds, bioautography of plant extracts were associated in an antioxidant screening. Due to containing variety of phenolic compounds Lavandula and Origanum species are important medicinal ... -
Biological activities of the natural coumarins from apiaceae plants
Tosun, Fatma; Biltekin, Sevde Nur; Karadağ, Ayşe Esra; Mıhoğlugil, Feyyaz; Akalgan, Demet; Miski, Mahmut (ACG Publications, 2023)Nineteen natural coumarins; badrakemin (1), colladonin (2), 14'-acetoxybadrakemin (3), anatolicin (4), 14'-hydroxycolladonin (5), badrakemone (6), karatavicinol (7), 14'-acetoxybadrakemone (8), 14'-acetoxycolladonin (9), ... -
Characterization of Opuntia ficus-indica (L.) Mill. fruit volatiles and antibacterial evaluation
Karadağ, Ayşe Esra; Demirci, Betül; Polat, Derya Çiçek; Okur, Mehmet Evren (Badebio Biotechnololgy Ltd, 2018)Opuntia ficus-indica (L.) Mill. fruits known as prickly pear cactus are used in folk medicine as well as food. In the present study it was aimed to extract the volatile constituents of O. ficus-indica fruits by n-hexane. ... -
Chemical characterization and multidirectional biological effects of different solvent extracts of arum elongatum: in vitro and in silico approaches
Fawzi Mahomoodally, Mohamad; Zengin, Gökhan; Roumita, Seebaluck-Sandoram; Caprioli, Giovanni; Mustafa, Ahmed M.; Piatti, Diletta; Yıldıztugay, Evren; Ak, Güneş; Karadağ, Ayşe Esra; Khalid, Asaad; Abdalla, Ashraf N.; İbrahim Uba, Abdullahi; Demirci, Fatih (Wiley-VCH Verlag, 2023)Arum elongatum (Araceae) is widely used traditionally for the treatment of abdominal pain, arterial hypertension, diabetes mellitus, rheumatism and hemorrhoids. This study investigated the antioxidant properties, individual ... -
Chemical characterization of Glaucosciadium cordifolium (Boiss.) B. L. Burtt & P. H. Davis essential oils and their antimicrobial, and antioxidant activities
Karadağ, Ayşe Esra; Demirci, Betül; Çeçen, Ömer; Tosun, Fatma (Istanbul University, 2019)Chemical composition of volatile oils obtained from the roots, fruits and aerial parts of Glaucosciadium cordifolium (Boiss.) B. L. Burtt& P. H. Davis (Apiaceae) were analyzed using gas chromatography-flame ionization ... -
Chemical compositon, antibacterial and antioxidant activities of Cnidium silaifolium ssp. orientale (Boiss.) Tutin essential oils
Karadağ, Ayşe Esra; Demirci, Betül; Çeçen, Ömer; Tosun, Fatma; Demirci, Fatih (Consejo Superior de Investigaciones Científicas (CSIC), 2021)The chemical compositions of the essential oils (EOs) obtained by hydrodistillation from different parts of Cnidium silaifolium ssp. orientale (Boiss.) Tutin were analyzed both by GC-FID and GC/MS, simultaneously. One ... -
Comparison of chemical profiles of aronia melanocarpa fruit extracts
Sönmez Gürer, Eda; Karadağ, Ayşe Esra; Altıntaş, Ayhan (Turkish Science and Technology Publishing (TURSTEP), 2023)The chokeberry plant, which is native to North America and the south of Canada, is a deciduous, shrub-shaped, berry-like plant belonging to the Rosaceae family, which survives for many years. It is seen as a plant that ... -
Design and synthesis of novel cylopentapyrazoles bearing 1,2,3-thiadiazole moiety as potent antifungal agents
Giray, Betül; Karadağ, Ayşe Esra; Şavluğ İpek, Özgecan; Pekel, Hanife; Güzel, Mustafa; Başpınar Küçük, Hatice (Elsevier, 2020)In drug-resistant phytopathogenic fungi, there has been extensive research on microbiological and antifungal drug development. In this study, a novel series of cylopentapyrazole bearing a 1,2,3-thiadiazole ring 2a-e were ... -
Development, characterization of naringenin-loaded promising microemulsion formulations, and demonstration of anti-aging efficacy by in vitro enzyme activity and gene expression
Şahin, Dilara; Çağlar, Emre Şefik; Boran, Tuğçe; Karadağ, Ayşe Esra; Özhan, Gül; Üstündağ Okur, Neslihan (Editions de Sante, 2023)This study aims to produce microemulsion formulations containing naringenin for anti-aging reasons. For this purpose, formulations of topical microemulsions including different cosurfactants and surfactants were developed, ... -
Enzyme-based antiviral potential of cinnamomum verum j. presl. essential oil and ıts major component (e)-cinnamaldehyde
In the present study, Cinnamomum verum J. Presl. bark essential oil and its main component cinnamaldehyde was evaluated in vitro for neuraminidase (NA), transmembrane serine protease (TMPRSS2), and angiotensin converting ... -
Evaluation of in vitro anti-cancer effects of Styphnolobium japonicum root extract in human colon (HT-9), brain (U-87), and prostate (PC-3) cancer cell lines
Okur, Mehmet Evren; Karakaş, Nihal; Karadağ, Ayşe Esra; Öztunç, Nurşah; Tosyalı, İbrahim Serkut; Demirci, Fatih (İstanbul University, 2020)Background and Aims: Styphnolobium japonicum (L.) Schott. (Sophora japonica) is a medicinal plant applied for various diseases, in the traditional medicine field. The evaluation of methanol extract of S. japonicum root ...