Yazar "Demirci, Fatih" için Eczacılık Fakültesi listeleme
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ACE2 and LOX enzyme inhibitions of different lavender essential oils and major components linalool and camphor
Biltekin, Sevde Nur; Karadağ, Ayşe Esra; Demirci, Betül; Demirci, Fatih (American Chemical Society, 2022)In this present study, Lavandula angustifolia, Lavandula stoechas, and Lavandula x heterophylla essential oils and their main compounds linalool and camphor were evaluated in vitro for lipoxygenase enzyme (LOX) and for ... -
Anti-inflammatory, analgesic and in vivo-in vitro wound healing potential of the Phlomis rigida Labill. extract
Okur, Mehmet Evren; Karadağ, Ayşe Esra; Özhan, Yağmur; Sipahi, Hande; Ayla, Şule; Daylan, Benay; Kültür, Şükran; Demirci, Betül; Demirci, Fatih (Elsevier Ireland Ltd, 2021)Ethnopharmacological relevance: The preparations of Phlomis aerial parts are used traditionally in Anatolia for wound healing and in inflammatory disorders. Methods: For the identification of the active fraction, the air ... -
Antimicrobial, anticholinesterase evaluation and chemical characterization of essential oil Phlomis kurdica Rech. fil. Growing in Turkey
Karadağ, Ayşe Esra; Demirci, Betül; Kültür, Şükran; Demirci, Fatih; Başer, K. Hüsnü Can (Taylor and Francis Inc., 2020)The Phlomis kurdica Rech.fil. (Lamiaceae) essential oil was investigated for its chemical constituents and in vitro biological activities. Volatile components were characterized, antimicrobial and anticholinesterase ... -
Binary synergistic combinations of lavender and fennel essential oils with amoxicillin
Karadaǧ, Ayşe Esra; Çaşkurlu, Ayşegül; Demirci, Betül; Demirci, Fatih (Georg Thieme Verlag, 2023)Microbial resistance is an important problem in modern healthcare systems. In addition to drug resistance, the side effects of current antibiotic applications are also known issues. In this present study, binary combinations ... -
Bioautography for evaluation of several Lavandula L. and origanum species antimicrobial and antioxidant activity
Karavuş, Şule Nur; Çaşkurlu, Ayşegül; Karadağ, Ayşe Esra; Demirci, Fatih (Istanbul Medipol University, 2023)In the search of bioactive natural compounds, bioautography of plant extracts were associated in an antioxidant screening. Due to containing variety of phenolic compounds Lavandula and Origanum species are important medicinal ... -
Chemical characterization and multidirectional biological effects of different solvent extracts of arum elongatum: in vitro and in silico approaches
Fawzi Mahomoodally, Mohamad; Zengin, Gökhan; Roumita, Seebaluck-Sandoram; Caprioli, Giovanni; Mustafa, Ahmed M.; Piatti, Diletta; Yıldıztugay, Evren; Ak, Güneş; Karadağ, Ayşe Esra; Khalid, Asaad; Abdalla, Ashraf N.; İbrahim Uba, Abdullahi; Demirci, Fatih (Wiley-VCH Verlag, 2023)Arum elongatum (Araceae) is widely used traditionally for the treatment of abdominal pain, arterial hypertension, diabetes mellitus, rheumatism and hemorrhoids. This study investigated the antioxidant properties, individual ... -
Chemical compositon, antibacterial and antioxidant activities of Cnidium silaifolium ssp. orientale (Boiss.) Tutin essential oils
Karadağ, Ayşe Esra; Demirci, Betül; Çeçen, Ömer; Tosun, Fatma; Demirci, Fatih (Consejo Superior de Investigaciones Científicas (CSIC), 2021)The chemical compositions of the essential oils (EOs) obtained by hydrodistillation from different parts of Cnidium silaifolium ssp. orientale (Boiss.) Tutin were analyzed both by GC-FID and GC/MS, simultaneously. One ... -
Enzyme-based antiviral potential of cinnamomum verum j. presl. essential oil and ıts major component (e)-cinnamaldehyde
In the present study, Cinnamomum verum J. Presl. bark essential oil and its main component cinnamaldehyde was evaluated in vitro for neuraminidase (NA), transmembrane serine protease (TMPRSS2), and angiotensin converting ... -
Evaluation of in vitro anti-cancer effects of Styphnolobium japonicum root extract in human colon (HT-9), brain (U-87), and prostate (PC-3) cancer cell lines
Okur, Mehmet Evren; Karakaş, Nihal; Karadağ, Ayşe Esra; Öztunç, Nurşah; Tosyalı, İbrahim Serkut; Demirci, Fatih (İstanbul University, 2020)Background and Aims: Styphnolobium japonicum (L.) Schott. (Sophora japonica) is a medicinal plant applied for various diseases, in the traditional medicine field. The evaluation of methanol extract of S. japonicum root ... -
Hemostatic activity of cistus creticus extract in wistar albino rats
Karadağ, Ayşe Esra; Çaşkurlu, Ayşegül; Okur, Mehmet Evren; Güzelmeriç, Etil; Üstündağ Okur, Neslihan; Tosun, Fatma; Yeşilada, Erdem; Demirci, Fatih (Springer Nature, 2020)Aerial part preparations of Cistus creticus L., Cistaceae, are traditionally used in Anatolia as a hemostatic agent. The air-dried aerial parts were extracted with methanol. Gels were prepared, followed by the hemostatic ... -
Herbal preparations used against fatty liver disease: Systematic review
Karadağ, Ayşe Esra; Demirci, Fatih (Turkiye Klinikleri, 2022)The fatty liver disease is defined as more than 5% of liver histiocytes filled with fatty vacuoles, depending on diet and indepen- dent of alcohol consumption. As it is known, fatty liver and related dis- orders are common, ... -
In vitro ACE2 and 5-LOX enzyme inhibition by menthol and three different mint essential oils
Demirci, Fatih; Karadağ, Ayşe Esra; Biltekin, Sevde Nur; Demirci, Betül (SAGE Publications Inc., 2021)Mentha arvensis L., M. citrata L., and M. spicata L. (family Lamiaceae) essential oils, and their characteristic constituent, menthol, were evaluated in vitro for angiotensin converting enzyme 2 (ACE2) and 5-lipoxygenase ... -
In vitro ACE2 and 5-LOX inhibition of rosmarinus officinalis l. essential oil and its major component 1,8-cineole
Demirci, Fatih; Karadağ, Ayşe Esra; Biltekin, Sevde Nur; Demirci, Betül (ACG Publications, 2022)In this present study, Rosmarinus officinalis L. essential oil, and its major component 1,8-cineole was evaluated in vitro for angiotensin converting enzyme 2 (ACE2), as well as for 5-lipoxygenase (5-LOX) enzyme inhibitory ... -
In vitro ACE2 enzyme inhibitory activity evaluation of different salvia essential oils
Karadağ, Ayşe Esra; Biltekin, Sevde Nur; Demirci, Betül; Demirci, Fatih (Istanbul Medipol University, 2022)In this present study, commertially available Salvia triloba L., S.officinalis L., and S. sclarea L. essential oils were evaluated for their in vitro angiotensin converting enzyme 2 (ACE2) inhibitory activity. The Salvia ... -
In vitro and in silico evaluation of ACE2 and LOX inhibitory activity of eucalyptus essential oils, 1,8-cineole, and citronellal
Ak Sakallı, Ezgi; Teralı, Kerem; Karadağ, Ayşe Esra; Biltekin, Sevde Nur; Koşar, Müberra; Demirci, Betül; Başer, Kemal Hüsnü Can; Demirci, Fatih (SAGE Publications Inc., 2022)Eucalyptus essential oils are well-known and used especially in upper respiratory tract pathologies or diseases as herbal drug preparations. In the present study, the in vitro angiotensin-converting enzyme 2 (ACE2) and ... -
In vitro and in silico evaluation of ACE2 and LOX inhibitory activity of origanum essential oils and carvacrol
Demirci, Fatih; Teralı, Kerem; Karadağ, Ayşe Esra; Biltekin, Sevde Nur; Ak Sakallı, Ezgi; Demirci, Betül; Koşar, Müberra; Başer, Kemal Hüsnü Can (Georg Thieme Verlag KG, 2023)Origanum spp. are used both for culinary purposes and for their biological activities. In this study, commercial Origanum majorana, Origanum minutiflorum, Origanum vulgare, and Origanum onites essential oils and their ... -
In vitro anti-inflammatory activities of Tanacetum parthenium L. extract and its major metabolite parthenolide
Baydar, Rengin; Karadağ, Ayşe Esra; Biltekin, Sevde Nur; Güzelmeriç, Etil; Demirci, Fatih (Istanbul Medipol University, 2024)Tanacetum parthenium L. (Feverfew) is daisy-like Asteraceae plant carrying sesquiterpene lactones; used for the treatment of migraine and anti-inflamma-tory effect. This study aims to evaluate T. parthenium extract and ... -
In vitro anti-inflammatory and anticancer evaluation of mentha spicata l. and matricaria chamomilla l. essential oils
Biltekin, Sevde Nur; Karadağ, Ayşe Esra; Demirci, Fatih; Demirci, Betül (American Chemical Society, 2023)Spearmint, Mentha spicata L., and the German chamomile, Matricaria chamomilla L., preparations are used against inflammatory conditions traditionally and in modern medicinal applications. This present study aimed to evaluate ... -
In vitro antibacterial, antioxidant, anti-inflammatory and analgesic evaluation of Rosmarinus officinalis L. flower extract fractions
Karadağ, Ayşe Esra; Demirci, Betül; Çaşkurlu, Ayşegül; Demirci, Fatih; Okur, Mehmet Evren; Orak, Deborah; Sipahi, Hande; Başer, Kemal Hüznü Can (Elsevier, 2019)Rosmarinus officinalis L. (rosemary) is a common culinary spice and herbal drug, which is used for centuries all over the world. In this present study, apolar to polar fractions of R. officinalis flowers were evaluated for ... -
In Vitro Antiviral Evaluations of Coldmix®: An Essential Oil Blend against SARS-CoV-2
Başer, Kemal Hüsnü Can; Karadağ, Ayşe Esra; Biltekin, Sevde Nur; Ertürk, Murat; Demirci, Fatih (NLM (Medline), 2023)Coldmix® is a commercially available Eucalyptus aetheroleum and, Abies aetheroleum blend for medicinal applications. In this present study, the in vitro antiviral potential of Coldmix®, and its major constituents 1,8-cineole ...