Browsing Uluslararası Tıp Fakültesi by Title
Now showing items 229-248 of 531
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Gender inequality in genitourinary malignancies clinical trials leadership
(Springer Science and Business Media Deutschland GmbH, 2024)Background Over the past 2 decades, there has been a growing interest in the signifcance of gender roles in healthcare and several eforts and initiatives have focused on increasing female representation in the medical ... -
Global consensus recommendations on menopause in the workplace: A European Menopause and Andropause Society (EMAS) position statement
(Elsevier Ireland Ltd, 2021)Introduction: Worldwide, there are 657 million women aged 45-59 and around half contribute to the labor force during their menopausal years. There is a diversity of experience of menopause in the workplace. It is shaped ... -
Global practice patterns and variations in the medical and surgical management of non-obstructive azoospermia: results of a world-wide survey, guidelines and expert recommendations
(2024)Purpose: Non-obstructive azoospermia (NOA) is a common, but complex problem, with multiple therapeutic options and a lack of clear guidelines. Hence, there is considerable controversy and marked variation in the management ... -
Global practice patterns in the evaluation of non-obstructive azoospermia: results of a world-wide survey and expert recommendations
(2024)Purpose: Non-obstructive azoospermia (NOA) represents the persistent absence of sperm in ejaculate without obstruction, stemming from diverse disease processes. This survey explores global practices in NOA diagnosis, ... -
Good versus poor prescribers: The comparison of prescribing competencies in primary care
(Cambridge University Press, 2022)Aim: To compare the competencies of primary care physicians (PCPs) with poor and good prescribing performance in frequently encountered indications. Background: Primary care centers are one of the mostly visited health ... -
Guiding empiric treatment for serious bacterial infections via point of care beta-lactamase characterization
(Ieee-Inst Electrical Electronics Engineers Inc, 2016)Fever is one of the most common symptoms of illness in infants and represents a clinical challenge due to the potential for serious bacterial infection. As delayed treatment for these infections has been correlated with ... -
Health services management in Turkey: Failure or success?
(Wolters Kluwer Medknow Publications, 2019)Background: The unfair distribution and delivery of health-care resources have been recognized as a problem in the worldwide. In the past 18 years, Turkey has undergone rapid social, cultural, and economic changes. The ... -
Health-related quality of life in localized renal masses: A matter of sparing nephrons or minimizing the incision?
(Elsevier Science Inc, 2020)Purpose: Longitudinal assessment of health-related quality of life (HRQoL) differences in patients with localized renal masses according to treatment strategy. Methods: Consecutive patients >= 18 years with localized renal ... -
Hedgehog signaling: Linking embryonic lung development and asthmatic airway remodeling
(MDPI, 2022)The development of the embryonic lung demands complex endodermal-mesodermal interactions, which are regulated by a variety of signaling proteins. Hedgehog (Hh) signaling is vital for lung development. It plays a key ... -
Helper innate lymphoid cells as cell therapy for cancer
(Wiley, 2023)Although the first cancer immunotherapy was given in the clinic more than a century ago, this line of treatment has remained more of a distant goal than a practical therapy due to limited understanding of the tumour ... -
Herpes simplex virus and SLE: Though uncommon yet with significant implications
(NLM (Medline), 2023)To the Editor,The relation between infectious agents, particularly viruses, withautoimmunity and autoimmune diseases, has been extensivelystudied during the last decades. Recently, the association was shownto be even ... -
Hexokinase 1 forms rings that regulate mitochondrial fission during energy stress
(2024)Metabolic enzymes can adapt during energy stress, but the consequences of these adaptations remain understudied. Here, we discovered that hexokinase 1 (HK1), a key glycolytic enzyme, forms rings around mitochondria during ... -
High-resolution mapping of sensory fibers at the healthy and post-myocardial infarct whole transgenic hearts
(Wiley, 2023)The sensory nervous system is critical to maintain cardiac function. As opposed to efferent innervation, less is known about cardiac afferents. For this, we mapped the VGLUT2-expressing cardiac afferent fibers of spinal ... -
Higher rates of COVID-19 but less severe infections reported for patients on dupilumab: A big data analysis of the world health organization vigibase
(Verduci Editore s.r.l, 2021)Objective: Dupilumab (Dupixent ®) is a monoclonal antibody that inhibits IL- 4 and IL-13 signaling used for the treatment of allergic diseases. Whilst biologic therapy is traditionally regarded as immunosuppressive and ... -
A histological atlas of the tissues and organs of neotenic and metamorphosed axolotl
(Elsevier GmbH, 2016)Axolotl (Ambystoma Mexicanum) has been emerging as a promising model in stem cell and regeneration researches due to its exceptional regenerative capacity. Although it represents lifelong lasting neoteny, induction to ... -
HIV pre-exposure prophylaxis and its impact on the gut microbiome in men having sex with men
(Frontiers Media S.A., 2022)HIV/AIDS still imposes a high epidemiological and societal burden. Together with antiretroviral therapy, pre-exposure prophylaxis (PrEP) represents a fundamental tool in the fight against HIV/AIDS. PrEP is considered ... -
Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism
(American Society for Clinical Investigation Inc, 2018)Defects in genes mediating thyroid hormone biosynthesis result in dyshormonogenic congenital hypothyroidism (CH). Here, we report homozygous truncating mutations in SLC26A7 in 6 unrelated families with goitrous CH and show ... -
A homozygous TPO gene duplication (c. 1184_1187dup4) causes congenital hypothyroidism in three siblings born to a consanguineous family
(Georg Thieme Verlag, 2015)Congenital hypothyroidism (CH) is the most common neonatal endocrine disease, and germ-line mutations in the TPO gene cause the inherited form of the disease. Our aim in this study was to determine the genetic basis of ...