Başlık için Uluslararası Tıp Fakültesi listeleme
Toplam kayıt 527, listelenen: 475-494
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Supratherapeutic utilization of paracetamol versus ibuprofen among <12-year-old children in primary care in Istanbul
(2024)Background: Paracetamol and ibuprofen are the most preferred analgesics for pain and fever management in children. Prescribing of these drugs in supratherapeutic doses may predispose to their toxicity. We aimed to compare ... -
Synthesis of novel hybrid lonidamine-coumarin derivatives and their anticancer activities
(Elsevier B.V., 2023)In order to develop drugs against cancer, which is one of the deadliest diseases in the world, hybridizing structures with known anticancer activity can provide a dual activity for the treatment of cancer cases. For this ... -
Synthesis of novel methyl jasmonate derivatives and evaluation of their biological activity in various cancer cell lines
(Academic Press Inc Elsevier Science, 2019)Warburg hypothesized that the energy consumption of cancer cells is different than the normal cells. When compared to normal conditions, cancer cells do not undergo tricarboxylic acid (TCA) cycle therefore resulting in ... -
Systematic review and cumulative analysis of the managements for proximal impacted ureteral stones
(Springer Verlag, 2019)Purpose: To compare the efficacy and safety of different treatment options for the management of proximal impacted ureteral stones (PIUS). Methods: A systematic literature search using Pubmed, Medline, Embase and Cochrane ... -
Systematic review and meta-analysis of tocilizumab therapy versus standard of care in over 15,000 COVID-19 pneumonia patients during the first eight months of the pandemic
(MDPI, 2021)Background. Tocilizumab is an anti-IL-6 therapy widely adopted in the management of the so-called "cytokine storm" related to SARS-CoV-2 virus infection, but its effectiveness, use in relation to concomitant corticosteroid ... -
Technical aspects and clinical limitations of sperm DNA fragmentation testing in male infertility: A global survey, current guidelines, and expert recommendations
(Korean Society for Sexual Medicine and Andrology, 2023)Purpose: Sperm DNA fragmentation (SDF) is a functional sperm abnormality that can impact reproductive potential, for which four assays have been described in the recently published sixth edition of the WHO laboratory manual ... -
Testis-sparing surgery in adult patients with germ cell tumors: Systematic search of the literature and focused review
(Elsevier, 2023)Testis-sparing surgery (TSS) is a guideline-recommended treatment option for men with synchronous or metachronous bilateral testicular germ-cell tumor (GCT) or GCT in a solitary testicle. The tumor volume should not exceed ... -
Therapeutic role of rifampicin in Alzheimer's disease
(Wiley, 2018)Rifampicin exerts significant brain protective functions in multiple experimental models. Here we summarize the underlying mechanisms of the neuroprotective and pro-cognitive effects of rifampicin that are mediated by its ... -
Time irreversibility of resting-state activity in the healthy brain and pathology
(Frontiers Media S.A., 2020)Characterizing brain activity at rest is of paramount importance to our understanding both of general principles of brain functioning and of the way brain dynamics is affected in the presence of neurological or psychiatric ... -
Tobacco use in breastfeeding mothers
(Springer International Publishing, 2023)Smoking is a major health hazard that remains very common worldwide. Nicotine is a highly addictive substance. There are in excess of 250 million female smokers globally. When expectant mothers continue to smoke, they not ... -
Topical estrogens and non-hormonal preparations for postmenopausal vulvovaginal atrophy: An EMAS clinical guide
(Elsevier Ireland Ltd, 2021)Introduction: Vulvovaginal atrophy (VVA) is a chronic condition caused by estrogen deficiency. It affects around 50% of postmenopausal women, reducing their general and sexual quality of life as well as the quality of their ... -
Traditional and complementary medicine perspectives of family physicians in Istanbul
(SERNEV, 2023)Introduction: The World Health Organization, within the scope of the Traditional Medicine Strategy for 2014-2023, recommends the development of integrated health policies, particularly in the area of primary healthcare. ... -
Transcription factor 4 gene rs9960767 polymorphism in bipolar disorder
(Spandidos Publications, 2016)The transcription factor 4 (TCF4) gene encodes a helix-loop-helix transcription factor protein, which initiates neuronal differentiation and is primarily expressed during nervous system development. The aim of the present ... -
Transfer and integration of breast milk stem cells to the brain of suckling pups
(Nature Publishing Group, 2018)Beside its unique nutritional content breast milk also contains live cells from the mother. Fate of these cells in the offspring has not been adequately described. In this study, we aimed to detect and identify maternal ... -
Transfer anxiety in critical care patients and their caregivers
(2020)Introduction: Family physicians play an important role for their critically ill patients and their caregivers. Both admission and discharge in the critical care units can cause anxiety in the patients and their family ... -
Transformation of acinetobacter baumannii: Electroporation
(Humana Press Inc., 2019)Although the pan and the core genome of Acinetobacter baumannii and its essential genes are relatively well characterized, functional characterization of these genes has not paralleled the genome-level studies. However, ... -
Transforming urinary stone disease management by artificial intelligence-based methods: A comprehensive review
(Elsevier, 2023)Objective: To provide a comprehensive review on the existing research and evi-dence regarding artificial intelligence (AI) applications in the assessment and management of urinary stone disease.Methods: A comprehensive ... -
Triggers and regulation: The gut microbiome in rheumatoid arthritis
(Taylor and Francis Ltd., 2023)Introduction Rheumatoid arthritis is a chronic inflammatory disease marked by systemic symptoms and joint degeneration. Interestingly, the development and progression of rheumatoid arthritis have been linked to the microbiome, ... -
Tumour microenvironment and focal therapy for prostate cancer
(Lippincott Williams & Wilkins, 2022)Purpose of review Although most studies focus on the tumour component of prostate cancer (PCa), increasing attention is being paid to the prostatic tumour microenvironment (TME) and its role in diagnosis, prognosis, and ... -
Turkish validation of the user version of the mobile application rating scale
(AVES, 2022)Objective: As the number of mobile health applications increases, quality assessment becomes a capital feature of any mobile application design. Besides the professional evaluation conducted before marketing the app, the ...
