Başlık için Uluslararası Tıp Fakültesi listeleme
Toplam kayıt 527, listelenen: 361-380
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Neuroprotective effects of curcumin-loaded emulsomes in a laser axotomy-induced CNS injury model
(Dove Medical Press Ltd, 2020)Purpose: Curcumin, a polyphenol isolated from the rhizomes of turmeric, holds great potential as a neuroprotective agent in addition to its anti-inflammatory and antioxidant characteristics. The poor bioavailability and ... -
The neuroprotective effects of hypothermia on bilirubin-ınduced neurotoxicity in vitro
(Karger, 2018)Background: In high-risk newborns indirect hyperbilirubinennia can lead to acute bilirubin encephalopathy and kernicterus. Despite the current therapeutic modalities, preventing or reversing the neurotoxicity cannot be ... -
The neutralization effect of montelukast on SARS-CoV-2 is shown by multiscale in silico simulations and combined in vitro studies
(Cell Press, 2022)Small molecule inhibitors have previously been investigated in different studies as possible therapeutics in the treatment of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). In the current drug repurposing ... -
Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and lymphocyte-monocyte ratio (LMR) in predicting systemic inflammatory response syndrome (SIRS) and sepsis after percutaneous nephrolithotomy (PNL)
(Springer, 2022)The objective of this prospective observational study was to assess the clinical significance of neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and lymphocyte-monocyte ratio (LMR) as potential biomarkers ... -
New-onset atrial fibrillation as poor outcome predictor in patients with severe COVID-19
(NLM (Medline), 2022)Tachyarrhythmias are common in patients with coronavirus disease 2019 (COVID-19), in particular those with severe disease. However, newly diagnosed atrial fibrillation (AF) during the course of severe COVID-19 seems to ... -
Newer advances in access
(Springer Nature, 2022)This chapter starts with an overview of the commonly used access direction technologies namely fluoroscopy and ultrasonography. Then an overview of the main novel technologies for access has been provided starting from ... -
Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels
(Elsevier B.V., 2022)Iron is an essential metal for cellular metabolism and signaling, but it has adverse effects in excess. The physiological consequences of iron deficiency are well established, yet the relationship between iron supplementation ... -
Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels (vol 53, 102319, 2022)
(Elsevier, 2022)The authors regret that the cited reference list in the online PDF of this article contains a duplicate reference (Ref 34 and incomplete Ref 56). Ref 56 should read as follows. -
Normobaric oxygen treatment improves neuronal survival functional recovery and axonal plasticity after newborn hypoxia-ischemia
(Elsevier, 2020)Background: Newborn hypoxia ischemia (HI) is one of the most prevalent cases in the emergency and can result from fetal hypoxia during delivery. In HI, restricted blood supply to the fetal brain may cause epilepsy or mental ... -
A novel candidate frameshift mutation for catecholaminergic polymorphic ventricular tchycardia
(Nature Publishing Group, 2019)... -
A novel insight into differential expression profiles of sporadic cerebral cavernous malformation patients with different symptoms
(Nature Research, 2021)Cerebral cavernous malformation (CCM) is a vascular lesion of the central nervous system that may lead to distinct symptoms among patients including cerebral hemorrhages, epileptic seizures, focal neurologic deficits, ... -
Novel synthetic approaches for bisnaphthalimidopropyl (BNIP) derivatives as potential anti-parasitic agents for the treatment of leishmaniasis
(MDPI, 2019)Leishmaniasis is a neglected parasitic disease that is widely seen in more than 60 countries worldwide, including Turkey and its subcontinental region. There are several chemotherapy agents for the treatment of leishmaniasis, ... -
A novel theanine complex, Mg-L-Theanine improves sleep quality via regulating brain electrochemical activity
(Frontiers Media S.A., 2022)L-Theanine is commonly used to improve sleep quality through inhibitory neurotransmitters. On the other hand, Mg2+, a natural NMDA antagonist and GABA agonist, has a critical role in sleep regulation. Using the caffeine-induced ... -
Novel β‑hydroxy ketones: Synthesis, spectroscopic characterization, molecular docking, and anticancer activity studies
(Elsevier B. V., 2022)In this study, a series of novel β‑hydroxy ketone derivatives 3a-o were designed, synthesized, and evaluated for their anticancer activity. The structure of these compounds were characterized by IR, 1H and 13C NMR, mass ... -
Numerical simulation modeling of the irreversible electroporation treatment zone for focal therapy of prostate cancer, correlation with whole-mount pathology and T2-weighted MRI sequences
(Sage Publications LTD, 2019)Background: At present, it is not possible to predict the ablation zone volume following irreversible electroporation (IRE) for prostate cancer (PCa). This study aimed to determine the necessary electrical field threshold ... -
Optogenetic manipulation of neuronal circuits regulating feeding behavior
(Wiley-Blackwell, 2015)... -
Osteoprotegerin genetic polymorphisms and their influence on therapeutic response to ibandronate in postmenopausal osteoporotic females
(Public Library of Science, 2023)ObjectivesThe present study investigated osteoprotegerin (OPG) genetic polymorphisms and their influence on the therapeutic response to ibandronate in postmenopausal osteoporotic females.MethodsThis case-control study ... -
Outcomes and complications from a randomized controlled study comparing conventional stent placement versus no stent placement after ureteroscopy for distal ureteric calculus < 1 cm
(MDPI, 2022)Ureteric stent insertion following ureteroscopic lithotripsy (URSL) is a common and widely accepted procedure. However, there is no agreement on whether a ureteric stent should be placed following an uncomplicated URSL. ... -
Over kanseri̇ne yöneli̇k fotodi̇nami̇k terapi̇ temelli̇ kombi̇nasyon terapi̇ uygulaması
(Zeynep Kamil Kadın ve Çocuk Hastalıkları Eğitim ve Araştırma Hastanesi, 2018)Kanser, tüm dünyada olduğu gibi ülkemizde de en ölümcül hastalıkların başında gelmektedir. Kanserin, lokal, minimum yan etkiyle ve hedefe yönelik olarak tedavisi hasta için büyük önem taşımaktadır. Fotodinamik Terapi (FDT), ... -
Overview of current pharmacotherapeutic options in benign prostatic hyperplasia
(Taylor and Francis Ltd., 2023)Introduction: Benign prostatic hyperplasia (BPH) represents the histological entity of prostate cell proliferation, which inflicts a gradually increasing obstruction of the bladder outlet and is accompanied by a progressing ...