Ara
Toplam kayıt 37, listelenen: 21-30
Investigation of the effects of methylphenidate, an amphetamine derivative, on intervertebral disc tissue cell cultures and matrix structures
(Turkish Neurosurgical Society, 2019)
AIM: To investigate the effects of methylphenidate (MPH), on intervertebral disc tissue (IVD) cell cultures and extracellular matrix structures. Changes in the expression of some important marker genes involved in anabolic ...
Delivering growth factors through a polymeric scaffold to cell cultures containing both nucleus pulposus and annulus fibrosus
(Turkish Neurosurgical Society, 2019)
AIM: To design a novel, polyvinyl alcohol (PVA)-based polymeric scaffold that permits the controlled release of insulin-like growth factor 1 (IGF-1) /bone morphogenetic protein (BMP)-2 following intervertebral disc ...
Is implant washing and wound irrigation with rifampicin effective for preventing surgical site infections in lumbar instrumentation?
(Turkish Neurosurgical Society, 2018)
AIM: To determine whether the washing of implants and autogenous bone grafts with rifampicin, and the irrigation of the surgical field using diluted rifampicin, have any significant effect on the prevention of spinal implant ...
Are specific gene expressions of extracellular matrix and nucleus pulposus affected by primary cell cultures prepared from intact or degenerative intervertebral disc tissues?
(Turkish Neurosurgical Society, 2019)
AIM: To determine the gene expression patterns of nucleus pulposus (NP) in cell cultures obtained from degenerated or intact tissues. MATERIAL and METHODS: Whereas 12 of the cases were diagnosed with lumbar disc herniation ...
Systematic evaluation of promising clinical trials-gene silencing for the treatment of glioblastoma
(Turkish Neurosurgical Society, 2019)
AIM: To systematically investigate the role of artificial small interfering RNA (SiRNA) molecules in glioblastoma treatment and to give a detailed overview of the literature concerning studies performed in this field ...
Is there a treatment protocol in which platelet-rich plasma is effective?
(Elsevier Science Bv, 2016)
Aim: We aimed to reveal whether there are prospective suggestions for effective and standard platelet-rich plasma applications. Methods: We searched for clinical trials and traced all the references of incorporated documents. ...
Evaluation of neutrophil-to-lymphocyte ratio as a marker of inflammatory response in septic arthritis
(Sage Publications, 2015)
Is neutrophil-to-lymphocyte ratio high in patients with septic arthritis? Septic arthritis may lead to higher rates of morbidity or even mortality if not diagnosed on time. This study was planned to answer the question ...
Pregabalin treatment for neuropathic pain may damage intervertebral disc tissue
(Spandidos Publications Ltd, 2018)
The aim of the present study was to determine whether pharmaceutical preparations with pregabalin (PGB) as an active ingredient, which are widely prescribed by clinicians, exert toxic effects on human primary nucleus ...
The association between different molecular weights of hyaluronic acid and CHAD, HIF-1 alpha, COL2A1 expression in chondrocyte cultures
(Spandidos Publications Ltd, 2018)
The aim of the present study was to investigate the effects of three different formulations of hyaluronic acid (HA): Low molecular weight (MW) Sinovial One((R)), medium MW Viscoplus((R)) and high MW Durolane((R)), on ...
Are radio-contrast agents commonly used in discography toxic to the intact intervertebral disc tissue cells?
(Wiley, 2019)
In the literature, there have been no studies showing clear results on how radio-contrast pharmaceuticals would affect intact disc tissue cells. In this context, it was aimed to evaluate the effects of iopromide and gadoxetic ...