Kurum Yazarı "Yiğitbaşı, Türkan" Tıp Fakültesi İçin Listeleme
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Comparison of the effects of clinical observation and protocol-based weaning on antioxidant stress factors
Erdoğan, Cem; Kızılaslan, Deniz; Tunay, Burcu; Karaaslan, Pelin; Ülfer, Gözde; Yiğitbaşı, Türkan; Demiraran, Yavuz; Öz, Hüseyin (NLM (Medline), 2022)BACKGROUND: We aimed to compare the effects of observation of the physician (POB) or by adhering to the protocol-based (PB) weaning methods on total antioxidant capacity (TAC) and total oxidative stress (TOS) levels and ... -
Could the increase in oxidative stress be the reason for the increased polyamine levels in diabetic obese and non-diabetic obese patients?
Göktürk, Nurcan; Şahin, Hicret; Bayramoğlu, Feyza; Çakıcı, Çağrı; Büyükuslu, Nihal; Yiğit, Pakize; Yiğitbaşı, Türkan (İstanbul Medipol University, 2022)Putresin, spermine, and spermidine are important polyamines found in all living organisms. In this study, as a first in the literature, we aimed to investigate polyamines levels and their relationship with oxidative stress ... -
COVID-19 pozitif hastalarda SARS-CoV-2 varyantlarının prevalansı
Aydoğan, Okan; Gözün Şaylan, Ezgi; Güven, Özlem; Ayaz, Akif; Yiğitbaşı, Türkan (DOC Design and Informatics Co. Ltd., 2022)Amaç: Dünya Sağlık Örgütü (DSÖ) tarafından alfa (B.1.1.7), beta (B.1.351), gamma (P.1), delta (B.1.617.2) ve omic - ron (B.1.1.529) endişe verici varyantlar (“variants of concern – VOCs”) olarak sınıflandırılmıştır. ... -
The effect of calpain inhibitor-I on copper oxide nanoparticle-induced damage and cerebral ischemia-reperfusion in a rat model
This study aimed to investigate the effects of the calpain inhibitor N-Acetyl-Leu-Leu-norleucinal (ALLN) on neuroapoptotic cell damage caused by Copper Oxide Nanoparticles (CuO-NP) and exacerbation of damage through brain ... -
The effect of low-level laser therapy on the oxidative stress level and quality of life in patients with Hashimoto’s thyroiditis
Tunç, Sümeyye; Altuntaş, Şükriye Leyla; Atmaca, Murat; Çakıcı, Çağrı; Yiğitbaşı, Türkan; Liou, Yeong Cheng; Chang, Wei An (2024)This study aimed to examine the effects of low-level laser therapy (LLLT) combined with levothyroxine replacement therapy on thyroid function, oxidative stress (OS), and quality of life in patients with Hashimoto’s thyroiditis ... -
Farede prematüre over yetmezliğinde mTERT telomeraz katalitik alt ünitesinin rolünün belirlenmesi
Memelilerde prenatal hayatta oluşan oosit rezervi, postnatal hayatta azalarak tükenmektedir. Foliküler atrezi olarak adlandırılan bu mekanizma ile ovariyal yaşlanma meydana gelmektedir. Primordiyal folikül havuzu tekrardan ... -
Ischemia-modified albumin levels in patients with bell's palsy
Cırık, Ahmet Adnan; Evcimik, Muhammed Fatih; Ülfer, Gözde; Yigitbaşı, Türkan; Aktaş, Öztürk (Wolters Kluwer Medknow Publications, 2022)Background: Although several causes have been regarded as possible including viral, autoimmune, inflammatory, and vascular ischemia, the accurate etiology and pathophysiology of Bell's palsy (BP) remain unclear. The aim ... -
LDH-A inhibitor as a remedy to potentiate the anticancer effect of docetaxel in prostate cancer
Çakıcı, Çağrı; Daylan, Benay; Ünlüer, Rüveyde Safiye; Emekli Alturfan, Ebru; Ayla, Şule; Eren Gözel, Hilal; Yiğit, Pakize; Yavuz Dokgöz, Elif; Yiğitbaşı, Türkan (Ivyspring International Publisher, 2024)Increased LDH-A activity promotes tumor growth, migration, invasion, and metastasis. This study aimed to investigate the effects of the combination of LDH-A inhibitor and Docetaxel on apoptosis and epithelial-mesenchymal ... -
The optimal method to measure polyamines in serum by using HPLC fluorescence detector
Çakan, Orhan; Hacıhasanoğlu Çakmak, Neziha; Bayramoğlu, Feyza; Yiğitbaşı, Türkan (Istanbul Medipol University, 2023)Measurement of polyamines (putrescine, spermidine and spermine) is important in the monitoring of many metabolic events, as well as in cancer prognosis. However, the lack of method standardization and validation for the ... -
Phosphorylation of PI3K/Akt at Thr308, but not phosphorylation of MAPK kinase, mediates lithium-induced neuroprotection against cerebral ischemia in mice
Ateş, Nilay; Çağlayan, Aysun; Balçıkanlı, Zeynep; Sertel, Elif; Beker, Mustafa Çağlar; Dilsiz, Pelin; Çağlayan, Ahmet Burak; Çelik, Süleyman; Daşdelen, Muhammed Furkan; Çağlayan, Berrak; Yiğitbaşı, Türkan; Özbek, Hanefi; Doeppner, Thorsten Roland; Hermann, Dirk Matthias; Kılıç, Ertuğrul (Academic Press Inc., 2022)Lithium, in addition to its effect on acute and long-term bipolar disorder, is involved in neuroprotection after ischemic stroke. Yet, its mechanism of action is still poorly understood, which was only limited to its ... -
Preoperative screening for COVID-19: Results from a clinical diagnostic laboratory
Aydoğan, Okan; Gözün Şaylan, Ezgi; Güven, Özlem; Ayaz, Akif; Yiğitbaşı, Türkan (Istanbul University, 2022)Objective: The study aimed to determine what proportion of Turkiye’s preoperative patient population has tested positive for COVID-19 and to ascertain whether the increasing or decreasing trend in the numbers of positive ... -
Prognostic and predictive role of liquid biopsy in lung cancer patients
Göksel, Tuncay; Özgür, Su; Tetik Vardarlı, Aslı; Koç, Altuğ; Soydaner Karakuş, Haydar; Özdemir, Taha Reşid; Erdoğan, Kadri Murat; Aldağ, Ceyda; Veral, Ali; Başbınar, Yasemin (Frontiers Media SA, 2024)Introduction Lung cancer (LC) is a leading cause of cancer-related mortality worldwide. Approximately 80% of LC cases are of the non-small cell lung cancer (NSCLC) type, and approximately two-thirds of these cases are ...