Ara
Toplam kayıt 27, listelenen: 11-20
Innovative methodologies in renewable energy: A review
(Wiley, 2019)
This paper is concerned with innovative approaches to renewable energy sources computation methodologies, which provide more refined results than the classical alternatives. Such refinements provide additional improvements ...
Trend analyses methodologies in hydro-meteorological records
(Springer International Publishing AG, 2020)
In recent years, global warming and climate change impacts on hydro-meteorological variables and water resources triggered extensive focus on trend analyses. Especially, in historical records and climate change model ...
Discussion of "Critical Values for Sen's trend analysis" by Richard H. McCuen
(American Society of Civil Engineers (ASCE), 2020)
It is well appreciated that the author of the original paper tried toavoid the qualitative subjectivity and proposed a quantitative approach for trend identification in a given hydrometeorology timeseries. He considered ...
A review of computational drug repositioning: Strategies, approaches, opportunities, challenges, and directions
(BMC, 2020)
Drug repositioning is the process of identifying novel therapeutic potentials for existing drugs and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an important role in optimizing the ...
Potential criteria for frameworks to support the evaluation of innovative medicines in upper middle-income countries-A systematic literature review on value frameworks and multi-criteria decision analyses
(Frontiers Media SA, 2020)
Background Multicriteria Decision Analysis (MCDA), a formal decision support framework, has been growing in popularity recently in the field of health care. MCDA can support pricing and reimbursement decisions on the macro ...
Reservoirs for water supply under climate change impact-A review
(Springer, 2021)
Arid region water reservoirs have different characteristics and solutions from humid regions with the most water shortage in the world socio-economically. This paper outlines possible implementation methodologies, procedures ...
An integrated framework for non-traditional machining process technology selection in healthcare applications
(Strojarski Facultet, 2022)
In spite of continuous progress in technical advancement, the conventional machining process became unsatisfactory in the healthcare field due to its disadvantages. This inadequacy lead researchers to consider using the ...
Modulation of protein-protein interactions for the development of effective therapeutics - from a joint perspective of experiment and computation
(Bentham Science Publishers B.V., 2018)
Many proteins present in living organisms act as obligate oligomers – that is to say - they require other protein partners to function properly. Oligomerization does not only lead to the formation of physical interactions, ...
Computational approaches in antibody-drug conjugate optimization for targeted cancer therapy
(Bentham Science Publishers Ltd, 2018)
Cancer has become one of the main leading causes of morbidity and mortality worldwide. One of the critical drawbacks of current cancer therapeutics has been the lack of the target-selectivity, as these drugs should have ...
Utilization of biased G protein-coupled receptor signaling towards development of safer and personalized therapeutics
(MDPI, 2019)
G protein-coupled receptors (GPCRs) are involved in a wide variety of physiological processes. Therefore, approximately 40% of currently prescribed drugs have targeted this receptor family. Discovery of beta-arrestin ...