dc.contributor.author | Yashar, Meltem | |
dc.contributor.author | Başarır, Kerem Edip | |
dc.contributor.author | Tanrıverdi, Elif Seren | |
dc.contributor.author | Celep, Selçuk | |
dc.contributor.author | Sirekbasan, Leyla | |
dc.contributor.author | Rakıcı, Erva | |
dc.contributor.author | Ejder, Nebahat | |
dc.contributor.author | Müsellim, Eda | |
dc.contributor.author | Çopur Çiçek, Ayşegül | |
dc.contributor.author | Yılmaz, Mesut | |
dc.date.accessioned | 2024-06-13T11:35:53Z | |
dc.date.available | 2024-06-13T11:35:53Z | |
dc.date.issued | 2024 | en_US |
dc.identifier.citation | Yashar, M., Başarır, K. E., Tanrıverdi, E. S., Celep, S., Sirekbasan, L., Rakıcı, E. ... Yılmaz, M. (2024). Stenotrophomonas maltophilia outbreak originating from a pull-out faucet in a pediatric intensive care unit in Turkey: Insights from clinical records and molecular typing. American Journal of Infection Control, 52(5), 605-610. http://dx.doi.org/10.1016/j.ajic.2023.11.018 | en_US |
dc.identifier.issn | 0196-6553 | |
dc.identifier.issn | 1527-3296 | |
dc.identifier.uri | http://dx.doi.org/10.1016/j.ajic.2023.11.018 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/12641 | |
dc.description.abstract | Background: Nosocomial Stenotrophomonas maltophilia-related cases are rising and pose a threat to immunocompromised patients. Twelve patients from our pediatric intensive care unit (PICU) presented with S maltophilia-associated bloodstream infection. Methods: This outbreak investigation includes 12 patients from PICU between the ages of 2 months and 4 years (mean 16 months, 7 male). To identify the origin, samples from all possible sources throughout the hospital were collected and ran through DNA isolation and Pulse Field Gel Electrophoresis. Results: 120 samples were collected during the outbreak. 31 samples (26%) were positive for S maltophilia. 30 S maltophilia isolates were analyzed, 10 different genotypes were identified. Clustering isolates were grouped into 3 different clusters (tolerance and optimization 1.0, cutoff 90%). The largest cluster was genotype 1, which included 19 isolates, those belong to patients’ samples and a sample from a pull-out faucet inside the PICU. The Pull-out faucet was the origin of the bloodstream infection. Discussion: Pull-out faucets allow biofilm production, due its structure. Pulse Field Gel Electrophoresis identifies the transmission dynamics of the outbreak, with its high discriminatory power. Conclusions: Water sources should be monitored on a regular basis. Pull-out faucets enable bacterial overgrowth; therefore, we recommend water surveillance during outbreak investigations. | en_US |
dc.language.iso | eng | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Faucet Aerator | en_US |
dc.subject | Genotype | en_US |
dc.subject | Immunocompromised Patients | en_US |
dc.subject | Outbreak-Investigation | en_US |
dc.subject | Stenotrophomonas Maltophilia Bacteremia | en_US |
dc.title | Stenotrophomonas maltophilia outbreak originating from a pull-out faucet in a pediatric intensive care unit in Turkey: Insights from clinical records and molecular typing | en_US |
dc.type | article | en_US |
dc.relation.ispartof | American Journal of Infection Control | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalı | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Mikrobiyoloji Ana Bilim Dalı | en_US |
dc.authorid | 0000-0003-4325-3430 | en_US |
dc.authorid | 0000-0002-3673-9670 | en_US |
dc.authorid | 0000-0001-8022-7325 | en_US |
dc.identifier.volume | 52 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.startpage | 605 | en_US |
dc.identifier.endpage | 610 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1016/j.ajic.2023.11.018 | en_US |
dc.institutionauthor | Yashar, Meltem | |
dc.institutionauthor | Başarır, Kerem Edip | |
dc.institutionauthor | Celep, Selçuk | |
dc.institutionauthor | Sirekbasan, Leyla | |
dc.institutionauthor | Müsellim, Eda | |
dc.institutionauthor | Çopur Çiçek, Ayşegül | |
dc.institutionauthor | Yılmaz, Mesut | |
dc.identifier.wosquality | Q1 | en_US |
dc.identifier.wos | 001233915100001 | en_US |
dc.identifier.scopus | 2-s2.0-85179810364 | en_US |
dc.identifier.pmid | 38043636 | en_US |
dc.identifier.scopusquality | Q1 | en_US |