dc.contributor.author | Süzen, Muazzez | |
dc.contributor.author | Zengin, Mustafa | |
dc.contributor.author | Çiftçi, Bahadır | |
dc.contributor.author | Uçkan, Sina | |
dc.date.accessioned | 2023-02-16T06:00:11Z | |
dc.date.available | 2023-02-16T06:00:11Z | |
dc.date.issued | 2023 | en_US |
dc.identifier.citation | Süzen, M., Zengin, M., Çiftçi, B. ve Uçkan, S. (2023). Does the vitamin C level affect postoperative analgesia in patients who undergo orthognathic surgery? International Journal of Oral and Maxillofacial Surgery, 52(2), 205-210. https://doi.org/10.1016/j.ijom.2022.06.005 | en_US |
dc.identifier.issn | 0901-5027 | |
dc.identifier.issn | 1399-0020 | |
dc.identifier.uri | https://doi.org/10.1016/j.ijom.2022.06.005 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/10454 | |
dc.description.abstract | Vitamin C has a critical role in pain management because of its antioxidative, neuroprotective, and anti-nociceptive properties. Oxidative stress caused by surgery increases the requirement for vitamin C. The aim of this study was to evaluate the change in vitamin C level and its effect on postoperative pain in patients undergoing orthognathic surgery. Thirty patients were included in the study. The relationships between the postoperative plasma vitamin C level, duration of surgery, postoperative analgesic consumption, and pain scores (visual analogue scale) were analysed. The difference between the mean pre-and postoperative vitamin C levels was found to be statistically significant (7.5 +/- 2.9 mg/l vs 4.9 +/- 2.3 mg/l, respectively; P = 0.001). There was no significant relationship between the duration of surgery and the vitamin C level decrease (P > 0.05). There was an inverse correlation between the postoperative vitamin C level and the amount of analgesic requested via patient-controlled analgesia (r = -0.699, P < 0.001). The findings suggest that, in patients who undergo orthognathic surgery, plasma vitamin C levels decrease significantly (34.6%), and an increase in the duration of surgery is not associated with any decrease in the vitamin C levels. A low postoperative plasma vitamin C level was found to be associated with greater postoperative analgesic consumption. In patients with preoperative plasma vitamin C levels <= 42 mu mol/l, perioperative vitamin C administration may be considered for postoperative pain management. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Churchill Livingstone | en_US |
dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
dc.subject | Orthognathic Surgery | en_US |
dc.subject | Vitamin C | en_US |
dc.subject | Oxidative Stress | en_US |
dc.subject | Postoperative Pain | en_US |
dc.subject | Analgesia | en_US |
dc.title | Does the vitamin C level affect postoperative analgesia in patients who undergo orthognathic surgery? | en_US |
dc.type | article | en_US |
dc.relation.ispartof | International Journal of Oral and Maxillofacial Surgery | en_US |
dc.department | İstanbul Medipol Üniversitesi, Diş Hekimliği Fakültesi, Ağız, Diş ve Çene Cerrahisi Ana Bilim Dalı | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Anesteziyoloji ve Reanimasyon Ana Bilim Dalı | en_US |
dc.authorid | 0000-0001-5121-9158 | en_US |
dc.authorid | 0000-0002-3245-6614 | en_US |
dc.authorid | 0000-0003-1077-7342 | en_US |
dc.identifier.volume | 52 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.startpage | 205 | en_US |
dc.identifier.endpage | 210 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1016/j.ijom.2022.06.005 | en_US |
dc.institutionauthor | Süzen, Muazzez | |
dc.institutionauthor | Zengin, Mustafa | |
dc.institutionauthor | Çiftçi, Bahadır | |
dc.institutionauthor | Uçkan, Sina | |
dc.identifier.wosquality | Q2 | en_US |
dc.identifier.wos | 000918335600001 | en_US |
dc.identifier.scopus | 2-s2.0-85133376366 | en_US |
dc.identifier.pmid | 35791994 | en_US |
dc.identifier.scopusquality | Q1 | en_US |