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dc.contributor.authorÜşümez, Aslıhan
dc.contributor.authorSarı, Tuğrul
dc.contributor.authorŞeşeoğulları Dirihan, Roda
dc.contributor.authorGüven, Mehmet Esad
dc.contributor.authorOğuz Ahmet, Serra
dc.contributor.authorGutknecht, Norbert
dc.contributor.authorTezvergil Mutluay, Arzu
dc.date.accessioned2022-12-27T11:02:35Z
dc.date.available2022-12-27T11:02:35Z
dc.date.issued2022en_US
dc.identifier.citationÜşümez, A., Sarı, T., Şeşeoğulları Dirihan, R., Güven, M. E., Oğuz Ahmet, S., Gutknecht, N. ... Tezvergil Mutluay, A. (2022). Effect of acid or laser treatment on degradation of dentin matrix. Lasers in Dental Science, 6(2), 99-105. https://doi.org/10.1007/s41547-022-00155-0en_US
dc.identifier.issn2367-2587
dc.identifier.urihttps://doi.org/10.1007/s41547-022-00155-0
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10194
dc.description.abstractPurpose: The objective of this study was to determine the effect of dental laser (DL) irradiation on the metalloproteinases (MMP)-mediated dentin collagen degradation. Methods: Human dentin disks were prepared (0.3 × 5x6mm, n = 60) and subjected to different treatments (n = 10/group): (1) control group (no treatment); (2) application of 37% phosphoric acid (PA) for 15 s; (3) irradiation with Er:YAG laser (120 mJ, 10 Hz); (4) irradiation with Er:YAG laser (120 mJ, 20 Hz); (5) irradiation with Er,Cr:YSGG laser (130mj, 30 Hz); and (6) irradiation with Er,Cr:YSGG laser (80mj, 50 Hz). After treatment, the total MMP activity and dry mass of each beam were measured, and after rehydration, they were incubated in 1 mL calcium- and zinc-containing incubation media for (a) one week and (b) three weeks. After each time point, dry mass changes were reassessed, and the aliquots of the incubation media were analyzed for pyridinoline-cross-link-containing degradation fragment of the C-terminal telopeptide of type I collagen (ICTP) using ELISA kits. All data were compared using ANOVA and Tukey’s test. Results: ANOVA showed significant differences among tested groups (p < 0.001). Laser-treated beams showed 55–75% less activity compared to 37% phosphoric acid-treated beams. The highest ICTP values were seen when PA was applied to the dentin surface in both time periods (p < 0.05). DL irradiation, be it with Er:YAG or Er,Cr:YSGG laser, did not increase the ICTP values in both time periods when compared with the control group (p > 0.05). Conclusion: The MMP-mediated dentin collagen degradation was the highest when PA was applied to the dentin surface and the lowest in Er:YAG or Er,Cr:YSGG laser-treated dentin groups in both time periods.en_US
dc.description.sponsorshipAcademy of Finland ; Turun Yliopistollinen Keskussairaalaen_US
dc.language.isoengen_US
dc.publisherSpringeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDentinen_US
dc.subjectEr,Cr:YSGG Laseren_US
dc.subjectEr:YAG Laseren_US
dc.subjectMMPen_US
dc.titleEffect of acid or laser treatment on degradation of dentin matrixen_US
dc.typearticleen_US
dc.relation.ispartofLasers in Dental Scienceen_US
dc.departmentİstanbul Medipol Üniversitesi, Diş Hekimliği Fakültesi, Protetik Diş Tedavisi Ana Bilim Dalıen_US
dc.authorid0000-0002-1387-2989en_US
dc.identifier.volume6en_US
dc.identifier.issue2en_US
dc.identifier.startpage99en_US
dc.identifier.endpage105en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1007/s41547-022-00155-0en_US
dc.institutionauthorOğuz Ahmet, Serra
dc.identifier.scopus2-s2.0-85129137819en_US


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