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Plasticity-promoting effect of melatonin after experimental cerebral ischemia
(Wiley-Blackwell, 2016)
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Evidence that activation of P2X7R does not exacerbate neuronal death after optic nerve transection and focal cerebral ischemia in mice
(Academic Press Inc Elsevier Science, 2017)
Conflicting data in the literature about the function of P2X7R in survival following ischemia necessitates the conductance of in-depth studies. To investigate the impacts of activation vs inhibition of the receptor on ...
Delayed therapeutic administration of melatonin enhances neuronal survival through AKT and MAPK signaling pathways following focal brain ischemia in mice
(Springer Nature, 2022)
Melatonin has a role in the cell survival signaling pathways as a candidate for secondary stroke prevention. Therefore, in the present study, the coordination of ipsilateral and contralateral hemispheres to evaluate delayed ...
Striatal dopaminergic neurons as a potential target for GDNF based ischemic stroke therapy
(Turkey Clinics, 2022)
Background/aim: Glial cell-line-derived neurotrophic factor (GDNF) is a well-known regulatory neurotrophic factor on dopaminergic neurons. Several pathologies have been documented so far in case of any impairment in the ...
Inflammatory cytokines are in action: Brain plasticity and recovery after brain ischemia due to delayed melatonin administration
(W.B. Saunders, 2021)
Objectives: Post-ischemic inflammation leads to apoptosis as an indirect cause of functional disabilities after the stroke. Melatonin may be a good candidate for the stroke recovery because of its anti-inflammatory effects. ...