Browsing by Author "Sargın, Deniz"
Now showing items 1-17 of 17
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Allogeneic hematopoietic stem cell transplantation for adult acute lymphoblastic leukemia: Results from a single center, 1993-2011
Yönal Hindilerden, İpek; Kalayoğlu Beşışık, Sevgi F.; Gürses-Koç, Nuray; Hindilerden, Fehmi; Sargın, Deniz (Tehran University of Medical Sciences (TUMS), 2017)Background: For adult ALL patients, the indications and appropriate timing of allogeneic hematopoietic stem cell transplantation (AHSCT) continue to be debated. The primary aim of this single-institution study was to compare ... -
Allogeneic stem cell transplantation in a blast-phase chronic myeloid leukemia patient with carbapenem-resistant Klebsiella pneumoniae tricuspid valve endocarditis: A case report
Kantarcıoğlu, Bülent; Beköz, Hüseyin Saffet; Olgun, Fatih Erkam; Çakal, Beytullah; Arkan, Burak; Türkoğlu, Halil; Mert, Ali; Sargın, Deniz (Spandidos Publications, 2016)In chronic myeloid leukemia (CML), the occurrence of blastic transformation is rare. Treatment outcome is generally poor. Allogeneic stem cell transplantation (allo-SCT) is the only potentially curative treatment option ... -
Clinical relevance of minor histocompatibility antigens
Savran Oğuz, Fatma; Kekik Çınar, Çiğdem; Oğuz, Seda B.; Sargın, Deniz; Kalayoğlu Beşışık, Sevgi (Pergamon-Elsevier Science, 2019)Objective: The minor histocompatibility antigens (MiHA) are epitopes composed of polymorphic essential peptides evoking alloimmune responses limited to a variety of human leukocyte antigen (HLA) alleles. These peptides are ... -
The clinical significance of IDH mutations in essential thrombocythemia and primary myelofibrosis
Yönal Hindilerden, İpek; Dağlar Aday, Aynur; Hindilerden, Fehmi; Akadam Teker, Başak; Yılmaz, Ceylan; Nalçacı, Meliha; Yavuz, Akif Selim; Sargın, Deniz (Elmer Press, 2016)Background: Limited data exist regarding impact of IDH mutations in Philadelphia-negative myeloproliferative neoplasms (Ph-negative MPNs). Prognostic significance of IDH mutations was asessed in 184 Ph-negative MPN patients ... -
Comparison of outcomes of total body irradiation (TBI) vs non-TBI conditioning regimens in acute lymphoblastic leukemia for allogeneic transplantation
Beköz, Hüseyin Saffet; Sevindik, Ömür Gökmen; Özçelik, Tülay; Arat, Mutlu; Hindilerden, İpek Yonal; Beşışık, Sevgi Kalayoğlu; Nalcacı, Meliha; Uzay, Ant; Kartı, Süleyman Sami; Kıvanç, Demet; Sargın, Deniz (Nature Publishing Group, 2019)... -
Complete remission of burkitt lymphoma after surgical excision: A case report
Beköz, Hüseyin Saffet; Kantarcıoğlu, Bülent; Tecimer, Tülay; Üskent, Necdet; Çetiner, Mustafa; Ferhanoğlu, Burhan; Sargın, Deniz (Springer India, 2016)Burkitt lymphoma (BL) is a highly aggressive B cell non-Hodgkin lymphoma that has a high proliferation rate. The prognosis for BL is generally favorable, with cure rate of 75-90 % with modern chemoimmunotherapy regimens. ... -
Effects of mutational combinations on philadelphia-negative myeloproliferative neoplasms
Yönal-Hindilerden, İpek; Dağlar-Aday, Aynur; Hindilerden, Fehmi; Nalcacı, Meliha; Akif, Selim Yavuz; Sargın, Deniz (Shiraz Univ Medical Sciences, 2017)Philadelphia-negative myeloproliferative neoplasms (MPNs) were first described 65 years ago. Yet, the molecular features of the disease have become of interest since 2005 following the identification of the JAK2V617F ... -
Immunoglobulin V(D) J recombination, protein ubiquitination, cell adhesion and sonic hedgehog gene variants are detected among familial multiple myeloma subjects following whole exome sequencing
Akkuş, Erman; Tunçali, Timur; Aydın, Yıldız; Kalayoğlu Beşışık, Sevgi; Gürkan, Emel; Ratip, Siret; Salihoğlu, Ayşe; Sargın, Deniz; Ünal, Ali; Turcan, Ayşegül; Beksaç, Meral (CIG Media Group, 2021)... -
The impact of donor specific anti-HLA antibodies on the outcome of allogeneic stem cell transplantation
Kekik, Çiğdem; Yönal Hindilerden, İpek; Savran Oğuz, Fatma; Usta, Sebahat; Temurhan, Sonay; Batu Demir, D.; Kalayoğlu Beşışık, Sevgi; Aktan, Melih; Sargın, Deniz (Nature Publishing Group, 2015)... -
Impact of HLA-DPB1 matching in unrelated allogeneic atem cell transplantation: Results of two centers from Turkey
Kantarcıoğlu, Bülent; Beköz, Hüseyin Saffet; Hindilerden, İpek Y.; Kıvanç, Demet; Öğret, Yeliz D.; Kalayoğlu Beşışık, Sevgi; Savran Oğuz, Fatma; Sargın, Deniz (Akad Doktorlar Yayınevi, 2017)In this study, we retrospectively examined 34 donor/recipient transplant pairs fully tested for the alleles HLA-A, B, C, DRB1, DQB1 and DPB1 in two different centers in Istanbul, Turkey. HLA-DPB1 disparity in at least one ... -
Infectious epidemiology in multiple myeloma patients after autologous stem cell transplantation: A single-center analysis from Turkey
Amikishiyev, Shirkhan; Yönal Hindilerden, İpek; Erdem, Simge; Aktan, Melih; Nalcacı, Meliha; Sargın, Deniz; Kalayoğlu Beşışık, Sevgi (Nature Publishing Group, 2018)... -
Isolated extramedullary cutaneous relapse despite concomitant severe graft-vs.-host disease and tissue chimerism analysis in a patient with acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation: A case report
Kantarcıoğlu, Bülent; Beköz, Hüseyin Saffet; Duvarcı Öğret, Yeliz; Çakır, Aslı; Kıvanç, Demet; Oğuz Savran, Fatma; Sargın, Deniz (Spandidos Publ Ltd., 2016)Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative treatment option for patients with acute lymphoblastic leukemia (ALL). The curative potential of allo-HSCT for ALL is, in part, due ... -
Preliminary report of the academic CAR-T (ISIKOK-19) cell clinical trial in Turkey: Characterization of product and outcomes of clinical application
Erdoğan, Ebru; Yalçın, Koray; Hemşinlioğlu, Cansu; Sezgin, Aslıhan; Seyis, Utku; Kançağı, Derya Dilek; Taştan, Cihan; Yurtsever, Bulut; Turan, Raife Dilek; Çakırsoy, Didem; Abanuz, Selen; Sır Karakuş, Gözde; Elek, Muhammer; Beköz, Hüseyin Saffet; Gemici, Aliihsan; Sargın, Deniz; Arat, Mutlu; Ferhanoğlu, Burhan; Pekgüç, Ebru; Örnek, Serdar; Büyüktaş, Deram; Birgen, Nur; Ratip, Siret; Ovalı, Ercüment (Turkish Society of Hematology, 2022)Objective: Chimeric antigen receptor T (CAR-T) cell therapies have already made an impact on the treatment of B-cell malignancies. Although CAR-T cell therapies are promising, there are concerns about commercial products ... -
A rare complication of hematopoietic stem cell transplantation: Kaposi sarcoma
Beköz, Hüseyin Saffet; Sağırlı, Ahmet Olcay; Türk, Osman Alperen; Ceylan, Bahadır; Sargın, Deniz (Pergamon-Elsevier Science, 2019)Background: Kaposi sarcoma is a neoplasm characterized by mucocutaneous and visceral angioproliferations that requires infection with human herpes virus (HHV)-8 for its development. The iatrogenic variant is ... -
Spontaneous regression of a systemic ALK (+) anaplastic large cell lymphoma carrying ALK gene rearrangement that developed after PPD tuberculin skin test
Beköz, Hüseyin Saffet; Kantarcıoğlu, Bülent; Tecimer, Tülay; Sargın, Deniz (Taylor & Francis, 2015)Here we report an ALK ( ) ALCL carrying ALK gene rearrangement that developed after a PPD tuberculin skin test, which spontaneously regressed after an excisional lymph node biopsy and is still in complete remission more ... -
Spontaneous regression of a systemic ALK (+) anaplastic large cell lymphoma carrying ALK gene rearrangement that developed after PPD tuberculin skin test
Beköz, Hüseyin Saffet; Kantarcıoğlu, Bülent; Tecimer, Tülay; Sargın, Deniz (Taylor & Francis Ltd, 2016)Here we report an ALK ( ) ALCL carrying ALK gene rearrangement that developed after a PPD tuberculin skin test, which spontaneously regressed after an excisional lymph node biopsy and is still in complete remission more ...
